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Cytochrome P450 Family 3 Subfamily A Member 4 (CYP3A4) small molecule antagonists: luciferase reporter qHTS assay
Assay data:1792 Active, 248 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2934 Active, 132 Activity ≤ 1 µM, 9667 Tested
Cytochrome P450 Family 2 Subfamily C Member 19 (CYP2C19) small molecule antagonists: luciferase reporter qHTS assay
Assay data:3508 Active, 4 Activity ≤ 1 nM, 319 Activity ≤ 1 µM, 9667 Tested
Caspase-3/7 induction in HepG2 cells by small molecules, qHTS cell viability counter screen
Assay data:693 Active, 37 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Caspase-3/7 induction in CHO-K1 cells by small molecules, qHTS cell viability counter screen
Assay data:1380 Active, 82 Activity ≤ 1 µM, 9667 Tested
Human pregnane X receptor (PXR) small molecule agonists, qHTS cell viability counter screen
Assay data:873 Active, 64 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule HDAC inhibitors: Summary
Assay data:421 Active, 16 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway in the presence of an antagonist - cell viability counter screen
Assay data:564 Active, 27 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway in the presence of an antagonist - cell viability counter screen
Assay data:756 Active, 46 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the sonic hedgehog signaling (Shh) pathway - cell viability counter screen
Assay data:714 Active, 57 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the sonic hedgehog signaling (Shh) pathway - cell viability counter screen
Assay data:750 Active, 58 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line in the presence of 0.1 nM 17-beta-estradiol - cell viability counter screen
Assay data:327 Active, 34 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen related receptor signaling pathway with the pleiotropic PPARgamma coactivator (PGC) from Tox21 10K library - cell viability counter screen
Assay data:526 Active, 61 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the constitutive androstane receptor (CAR) signaling pathway - cell viability counter screen
Assay data:494 Active, 60 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen related receptor (ERR) signaling pathway from Tox21 library - cell viability counter screen
Assay data:991 Active, 83 Activity ≤ 1 µM, 9667 Tested
GENE-TOX mutagenicity studies
Assay data:1995 Active, 3214 Tested
SummaryCompounds, Active
CCRIS mutagenicity studies
Assay data:4929 Active, 8266 Tested
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary
Assay data:372 Active, 6 Activity ≤ 1 nM, 228 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen
Assay data:467 Active, 55 Activity ≤ 1 µM, 10486 Tested
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