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Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: L363_DSMZ cell viability assay
Assay data:540 Active, 30 Activity ≤ 1 nM, 593 Activity ≤ 1 µM, 1912 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS26_JCRB cell viability assay
Assay data:699 Active, 23 Activity ≤ 1 nM, 366 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS12PE_JCRB cell viability assay
Assay data:722 Active, 26 Activity ≤ 1 nM, 377 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS27_JCRB cell viability assay
Assay data:640 Active, 26 Activity ≤ 1 nM, 465 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: JJN3_DSMZ cell viability assay
Assay data:743 Active, 23 Activity ≤ 1 nM, 495 Activity ≤ 1 µM, 1912 Tested
Anesthetic activity in Xenopus laevis tadpoles assessed as increase in loss of righting reflex incubated for 30 to 60 mins
Assay data:2 Active, 1 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Cmax in Beagle dog at 6.9 mg/kg, po by LC-MS/MS analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approved drugs and bioactive compounds
Assay data:1106 Active, 14 Activity ≤ 1 nM, 6478 Activity ≤ 1 µM, 7578 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
qHTS assay to identify small molecule antagonists of the sonic hedgehog signaling (Shh) pathway
Assay data:1356 Active, 2 Activity ≤ 1 nM, 487 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
BK Channel Variant Modulator Selectivity Assay
Assay data:286 Active, 904 Activity ≤ 1 nM, 951 Activity ≤ 1 µM, 951 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the endoplasmic reticulum stress response signaling pathway
Assay data:29 Active, 6 Activity ≤ 1 nM, 218 Activity ≤ 1 µM, 9315 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation
Assay data:74 Activity ≤ 1 nM, 704 Activity ≤ 1 µM, 2023 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen
Assay data:410 Active, 2 Activity ≤ 1 nM, 209 Activity ≤ 1 µM, 9305 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS for Inhibitors of Polymerase Iota
Assay data:4029 Active, 1388 Activity ≤ 1 µM, 391277 Tested
qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a
Assay data:31109 Active, 1 Activity ≤ 1 nM, 5166 Activity ≤ 1 µM, 353740 Tested
Agonist activity at GABAA assessed as enhancement of channel current
Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested
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