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GPCRScan assay: inhibition of Sigma 2
Assay data:29 Active, 24 Activity ≤ 1 µM, 181 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
GPCRScan assay: inhibition of H2
Assay data:5 Active, 4 Activity ≤ 1 µM, 165 Tested
GPCRScan assay: inhibition of DAT
Assay data:18 Active, 7 Activity ≤ 1 µM, 181 Tested
GPCRScan assay: inhibition of NET
Assay data:6 Active, 2 Activity ≤ 1 µM, 181 Tested
GPCRScan assay: inhibition of SERT
Assay data:5 Active, 4 Activity ≤ 1 µM, 181 Tested
Serotonin-uptake assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Dopamine-uptake assay
A?40 inhibition assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
A?42 inhibition assay
Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: luciferase cell-based qHTS assay
Assay data:2147 Active, 1 Activity ≤ 1 nM, 377 Activity ≤ 1 µM, 5242 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approved drugs and bioactive compounds
Assay data:1106 Active, 14 Activity ≤ 1 nM, 6478 Activity ≤ 1 µM, 7578 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Inhibition of SERT (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of gamma-secretase in human SH-SY5Y cells expressing beta-APP C-terminal fragment SPA4CT assessed as decrease of amyloid beta-42 level by electrochemiluminescent method
Assay data:22 Active, 19 Activity ≤ 1 µM, 22 Tested
Inhibition of gamma-secretase in human SH-SY5Y cells expressing beta-APP C-terminal fragment SPA4CT assessed as decrease of amyloid beta-40 level by electrochemiluminescent method
Assay data:22 Active, 11 Activity ≤ 1 µM, 22 Tested
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