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Synergistic cytotoxicity against human NCI-H1299 cells measured in presence of 50 nM AZD0156 after 6 days by SRB assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Synergistic cytotoxicity against human NCI-H1299 cells measured in presence of 5 uM KU60019 after 6 days by SRB assay
Synergistic cytotoxicity against human SW480 cells measured after 9 days in presence of 50 nM AZD0156 by SRB assay
Synergistic cytotoxicity against human SW480 cells measured after 9 days in presence of 5 uM KU60019 by SRB assay
Additive cytotoxicity against human SW480 cells measured after 9 days in presence of 5 uM KU55933 by SRB assay
Cytotoxicity against human SW480 cells measured after 9 days in presence of 5 uM 2(((24(2,4-dichlorobenzyl)oxy)naphthalen-1-yl)methyl)amino)ethan-1-ol by SRB assay
Cytotoxicity against human MCF7 cells assessed as combination index measured after 6 days in presence of 5 uM 2(((24(2,4-dichlorobenzyl)oxy)naphthalen-1-yl)methyl)amino)ethan-1-ol by SRB assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Synergistic cytotoxicity against human MCF7 cells measured after 6 days in presence of 50 nM AZD0156 by SRB assay
Antiproliferative activity against human LS174T cells harboring beta-catenin mutant assessed as reduction in cell viability measured after 72 hrs by SRB assay
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Antiproliferative activity against human HCT-116 cells harboring beta-catenin mutant assessed as reduction in cell viability measured after 72 hrs by SRB assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 3 Tested
Antiproliferative activity against human RKO cells harboring wild type beta-catenin assessed as reduction in cell viability measured after 72 hrs by SRB assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested
Antiproliferative activity against etoposide/cisplatin combination-resistant human NCI-H446 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Assay data:5 Active, 2 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Antiproliferative activity against Irinotecan-resistant human NCI-H446 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Antiproliferative activity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Assay data:5 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Cytotoxicity against human NCI-H526 cells assessed as reduction in cell viability incubated for 72 hrs by PrestoBlue reagent based assay
Assay data:6 Active, 6 Activity ≤ 1 µM, 7 Tested
Cytotoxicity against human MCF7 cells by MTT assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 13 Tested
Primary qHTS for Inhibitors of ATXN expression
Assay data:2593 Active, 3 Activity ≤ 1 nM, 2671 Activity ≤ 1 µM, 361713 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Anticancer activity against human T84 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Anticancer activity against human SW-620 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
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