BioAssays, activity concentration at/below 1 nM for PubChem Compound ( - PubChem BioAssay - NCBI

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Items: 10

Select item 19205131.

Inhibition of wild type TRAK (unknown origin) incubated for 30 mins by caliper mobility shift assay

Source:: ChEMBL

Protein Target:: High affinity nerve growth factor receptor

Assay data:15 Active, 3 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 18 Tested

AID:: 1920513

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18890672.

Inhibition of TRKA (unknown origin) by radiometric assay

Source:: ChEMBL

Protein Target:: High affinity nerve growth factor receptor

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1889067

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18780963.

Inhibition of ROS1 (unknown origin)

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase ROS

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1878096

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18780954.

Inhibition of TrkC (unknown origin)

Source:: ChEMBL

Protein Target:: NT-3 growth factor receptor

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1878095

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18780945.

Inhibition of TrkB (unknown origin)

Source:: ChEMBL

Protein Target:: BDNF/NT-3 growth factors receptor

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1878094

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18780936.

Inhibition of TrkA (unknown origin)

Source:: ChEMBL

Protein Target:: High affinity nerve growth factor receptor

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1878093

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18127477.

Inhibition of TrkA (unknown origin) by radiometric assay

Source:: ChEMBL

Protein Target:: High affinity nerve growth factor receptor

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1812747

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18097358.

Inhibition of TRKA (unknown origin) by radiometric assay

Source:: ChEMBL

Protein Target:: High affinity nerve growth factor receptor

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1809735

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16010149.

Inhibition of human wild type TrkA kinase domain expressed in mouse NIH/3T3 cells by HTRF assay

Source:: ChEMBL

Protein Target:: High affinity nerve growth factor receptor

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1601014

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 130045610.

Inhibition of TRKA (unknown origin) in presence of gamma33-ATP

Source:: ChEMBL

Protein Target:: High affinity nerve growth factor receptor

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1300456

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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BioActivity

Active Compounds (10)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (10)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (10)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (10)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (10)
BioAssays extracted from the literature

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