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Inhibition of SARS-CoV-2-induced cytopathy was measured 4 days after infection of EGFP-labeled Green monkey Vero cells by fluorescence imaging.
Assay data:19 Active, 7 Activity ≤ 1 µM, 134 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Assay data:281 Active, 189401 Tested
SummaryCompounds, Active
Primary redox qHTS assay for identification of artifact compounds.
Assay data:19 Active, 16 Activity ≤ 1 µM, 5098 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Primary Nanoluciferase (NLuc) qHTS assay for identification of artifact compounds.
Assay data:37 Active, 2 Activity ≤ 1 µM, 5098 Tested
Primary fluorescence-based thiol-reactive (MSTI) qHTS assay for identification of artifact compounds.
Assay data:494 Active, 184 Activity ≤ 1 µM, 5098 Tested
Primary firefly luciferase (FLuc) qHTS assay for identification of artifact compounds.
Assay data:75 Active, 14 Activity ≤ 1 µM, 5098 Tested
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
NCI human tumor cell line growth inhibition assay. Data for the A498 Non-Small Cell Lung cell line, single concentration
Assay data:3589 Active, 71200 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Assay data:237 Active, 1947 Activity ≤ 1 µM, 141380 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
GF-AFC viability counterscreen for inhibitors of alpha-synuclein gene (SNCA) expression
Assay data:177 Active, 2 Activity ≤ 1 nM, 481 Activity ≤ 1 µM, 146379 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Primary qHTS assay for inhibitors of Glutamate pyruvate transaminase 2 (GPT2)
Assay data:249 Active, 449 Activity ≤ 1 µM, 100803 Tested
Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (IP6K1)
Assay data:1159 Active, 143951 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry
Assay data:368 Active, 78 Activity ≤ 1 µM, 5114 Tested
Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Assay data:158 Active, 29 Activity ≤ 1 µM, 5114 Tested
A screen for small molecules that modulate mitochondrial supercomplex formation
Assay data:101 Active, 2017 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of EML4/ALK in human DFCI032 cells assessed as reduction in ALK mediated Akt phosphorylation at 0.1 to 1 uM by Western blot analysis
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antimicrobial activity against autoluminescent Mycobacterium tuberculosis H37Ra infected in BALB/c mouse assessed as reduction in bacterial burden in spleen at 300 mg/kg administered daily via gavage for 5 days and measured on day 6 by luminometric method
Assay data:1 Tested
SummaryPubMed Citation
Primary qHTS for Identification of Calcium Integrin Binding Protein 1 (CIB1) Competitor
Assay data:56 Active, 15 Activity ≤ 1 µM, 13474 Tested
Stabilization of p53 in human papillomavirus-positive cells
Assay data:83 Active, 5741 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
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