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Items: 8

1.

qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway

Source:
National Center for Advancing Translational Sciences (NCATS)
Protein Target:
nuclear factor NF-kappa-B p105 subunit isoform 1

Assay data:10 Active,  1 Activity ≤ 1 nM,  6 Activity ≤ 1 µM,  2864 Tested

AID:
651749

SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target

2.

Summary of the probe development efforts to identify dual inhibitors of signal transducer and activator of transcription 3 (STAT3) and nuclear factor NF-kappa-B (NF-kB)

Source:
The Scripps Research Institute Molecular Screening Center
Protein Targets:
STAT3, partial; ...
Total:
2

AID:
624358

SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target

3.

Late stage assay provider counterscreen results from the probe development effort to identify STAT5 inhibitors: luminescence-based cell-based reporter assay to identify inhibitors of NFkB signaling

Source:
The Scripps Research Institute Molecular Screening Center
Protein Target:
nuclear factor NF-kappa-B p105 subunit isoform 1

Assay data:1 Active,  11 Tested

AID:
652028

SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target

4.

NF-KappaB Measured in Biochemical System Using Small Molecule MicroArray - 2080-01_Other_SinglePoint_HTS_Activity

Source:
Broad Institute
Protein Target:
nuclear factor NF-kappa-B p105 subunit isoform 1

Assay data:218 Active,  16958 Tested

AID:
624139

SummaryCompounds, ActiveRelated BioAssays by Target

5.

Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response

Source:
SRMLSC
Protein Targets:
nuclear factor NF-kappa-B p105 subunit isoform 1; ...
Total:
2

Assay data:842 Active,  161 Activity ≤ 1 µM,  1242 Tested

AID:
1241

SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target

6.

Counterscreen assay for STAT3 activators: Cell-based high throughput assay to measure NF-kappaB activation

Source:
The Scripps Research Institute Molecular Screening Center
Protein Target:
nuclear factor NF-kappa-B p105 subunit isoform 1

Assay data:132 Active,  1197 Tested

AID:
1309

SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target

7.

Counterscreen assay for STAT3 inhibitors: Cell-based high throughput assay to measure NF-kappaB inhibition.

Source:
The Scripps Research Institute Molecular Screening Center
Protein Target:
nuclear factor NF-kappa-B p105 subunit isoform 1

Assay data:438 Active,  1215 Tested

AID:
1308

SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target

8.

High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen

Source:
SRMLSC
Protein Targets:
nuclear factor NF-kappa-B p105 subunit isoform 1; ...
Total:
2

Assay data:3101 Active,  193297 Tested

AID:
1239

SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target

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