BioAssay by Target (List) for Protein (Select 4506055) - PubChem BioAssay - NCBI

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Items: 6

Select item 5886291.

Protein Kinase A Activity Assay Measured in Biochemical System Using Plate Reader - 2052-04_Inhibitor_Dose_DryPowder_Activity_Set2

Source:: Broad Institute

Protein Target:: cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1

Assay data:6 Active, 2 Activity ≤ 1 µM, 82 Tested

AID:: 588629

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 5045832.

Protein Kinase A Activity Assay Measured in Biochemical System Using Plate Reader - 2052-04_Inhibitor_Dose_DryPowder_Activity

Source:: Broad Institute

Protein Target:: cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1

Assay data:3 Active, 1 Activity ≤ 1 µM, 29 Tested

AID:: 504583

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 5483.

Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1

Assay data:62 Active, 94 Tested

AID:: 548

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Target

Select item 5244.

Primary biochemical high-throughput screening assay for inhibitors of protein kinase A (PKA) activity

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1

Assay data:94 Active, 64925 Tested

AID:: 524

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Target

Select item 19825.

Kinase inhibition selectivity assay for compound SID-48409448

Source:: Burnham Center for Chemical Genomics

Protein Targets:: 3-phosphoinositide-dependent protein kinase 1 isoform 1; ...
Total:: 314

Assay data:1 Active, 1 Tested

AID:: 1982

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 14336.

Kinase Inhibitor Selectivity Profiling Assay

Source:: Ambit Biosciences

Protein Targets:: 3-phosphoinositide-dependent protein kinase 1 isoform 1; ...
Total:: 287

Assay data:38 Active, 14 Activity ≤ 1 nM, 38 Activity ≤ 1 µM, 38 Tested

AID:: 1433

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (6)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (6)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (3)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (3)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

NIH MLP (5)
BioAssays deposited by the NIH Molecular Libraries Program
Other (1)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Protein (Select 4506055) (6)
PubChem BioAssay
Cyttopsis rosea isolate BE22-LC-AS-V-83 cytochrome c oxidase subunit I (COX1) ge...
Cyttopsis rosea isolate BE22-LC-AS-V-83 cytochrome c oxidase subunit I (COX1) gene, partial cds; mitochondrial
gi|2734035245|gb|PP813569.1|

Nucleotide

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