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Human beta1-adrenoceptor (Adrenoceptors)
Assay data:43 Active, 43 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Development of the first CNS penetrant Muscarinic 5 (M5) Positive Allosteric Modulator based on a novel non-isatin core
Assay data:1 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Development of a novel orthosteric Muscarinic 5 (M5) antagonist possessing a hig degree of muscarinic subtype selectivity
Discovery and characterization of a small molecule allosteric agonists of mas-related G-Protein coupled receptor X1 ( MrgX1)
Development of the First Potent, Selective and CNS penetrant M5 Negative Allosteric Modulator (NAM)
Development of inhibitors for mGluR7 (Eurofin Panel Assay Results)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Development of inhibitors for Menin-MLL Receptor(Eurofin Panel Assay Results)
Development of inhibitors for mGluR7/8 (Eurofin Panel Assay Results)
SummaryRelated BioAssays by Target
Development of inhibitors for PLD2 (Eurofin Panel Assay Results)
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Development of inhibitors for Dopamine D4 Receptors: Eurofin Panel Assay Results
ML353 Eurofin Panel Assay for mGlu5 SAM Inhibitor (Probe Compound)
ML354 Eurofin Panel Assay for PAR4 Antagonists Inhibitor (Probe Compound)
ML352 Eurofin Panel Assay for Choline Transporter Inhibitor (Probe Compound)
ML347 Eurofin Panel Assay for BMP Inhibitor (Probe Compound)
High throughput discovery of novel modulators of ROMK K+ channel activity: Ancillary Activity
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator: Ancillary Activity
Assay data:2 Tested
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Antagonist Ancillary Profile
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist Ancillary Activity
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