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Human CFTR (CFTR)
Assay data:18 Active, 18 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in HeLa Cells
Assay data:14 Active, 1 Activity ≤ 1 µM, 10020 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
SAR analysis of molecule cystic fibrosis induced NFkb Inhibitors in a panel assay
Assay data:35 Active, 4 Activity ≤ 1 µM, 35 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Dose Response confirmation of uHTS small molecule hits for cystic fibrosis induced NFkb Inhibitors in a panel assay
Assay data:706 Active, 737 Tested
Late-stage results from the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70): yellow fluorescent protein (YFP) quenching assay to assess changes in trafficking of DeltaF508-CFTR
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Summary assay for small molecule cystic fibrosis induced NFkb Inhibitors
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Fluorescence Polarization with CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-02_Inhibitor_Dose_CherryPick_Activity
Assay data:13 Active, 453 Tested
Fluorescence Polarization with CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-02_Inhibitor_Dose_DryPowder_Activity
Assay data:4 Active, 8 Tested
Fluorescence Polarization with CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-02_Inhibitor_Dose_CherryPick_Activity_Set2
Assay data:9 Active, 1037 Tested
Fluorescence Polarization with Cer CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-01_Inhibitor_Dose_DryPowder_Activity
Assay data:2 Active, 8 Tested
Single concentration confirmation of uHTS hits for cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
Assay data:833 Active, 1302 Tested
Fluorescence Polarization with CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-02_Inhibitor_SinglePoint_HTS_Activity
Assay data:2737 Active, 296686 Tested
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
Assay data:3107 Active, 359521 Tested
Broad Institute Small-molecule targeting of CFTR: PDZ Trafficking Interactions Inhibitor Probe Project
Fluorescence Polarization with Cer CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-01_Inhibitor_Dose_CherryPick_Activity
Assay data:29 Active, 453 Tested
Fluorescence Polarization with Cer CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-01_Inhibitor_SinglePoint_HTS_Activity
Assay data:54 Active, 327011 Tested
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