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Cytotoxicity against hamster BHK-21 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Assay data:1 Active, 3 Tested
Summary
Cytotoxicity against hamster BHK-21 cells incubated for 4 days by MTS assay
Assay data:2 Active, 14 Tested
Cytotoxicity against Golden hamster BHK cells assessed as lethality incubated for 48 hrs by Alamar blue based colorimetric assay
Assay data:6 Tested
Inhibition of hamster liver SOAT
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Cmax in Syrian hamster at 100 mg/kg, po
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Cytotoxicity against golden hamster BHK-21 cells incubated for 24 hrs by ATP-lite assay
Assay data:1 Tested
Cytotoxicity against golden hamster BHK-21 cells incubated for 24 hrs by CCK-8 assay
Invivo antiprotozoal activity against Leishmania donovani amastigotes in hamster spleen assessed as reduction of amastigotes count measured after 7 days relative to control
Cytotoxicity against hamster BHK-21 cells assessed as reduction in cell viability at MOI of 0.01 incubated for 48 hrs by plaque formation assay
Assay data:2 Tested
SummaryPubMed Citation
Antidyslipidemic activity in Triton-induced hyperlipidemic Syrian golden hamster model assessed as increase in lecithin-cholesterol acyltransferase level at 50 mg/kg measured after 18 hrs
Assay data:22 Tested
Antidyslipidemic activity in Triton-induced hyperlipidemic Syrian golden hamster model assessed as decrease in total cholesterol level at 50 mg/kg measured after 18 hrs
Antidyslipidemic activity in Triton-induced hyperlipidemic Syrian golden hamster model assessed as decrease in triglyceride level at 50 mg/kg measured after 18 hrs
Antidyslipidemic activity in Triton-induced hyperlipidemic Syrian golden hamster model assessed as decrease in PL level at 50 mg/kg measured after 18 hrs
Antidyslipidemic activity in Triton-induced hyperlipidemic Syrian golden hamster model assessed as increase in post-heparin lipolytic activity at 50 mg/kg measured after 18 hrs
Cytotoxicity against hamster BHK-21 cells assessed as reduction in cell viability at 10 uM measured after 3 days
Assay data:13 Tested
Hypolipidemic activity in high fat diet induced Syrian golden hamster assessed as decrease in triglyceride level at 30 mg/kg,ip administered once daily for 21 days by automatic biochemical analyzer
Assay data:1 Active, 1 Tested
Hypolipidemic activity in high fat diet induced Syrian golden hamster assessed as decrease in total cholesterol level at 30 mg/kg,ip administered once daily for 21 days by automatic biochemical analyzer
Hypolipidemic activity in high fat diet induced Syrian golden hamster assessed as decrease in low-density lipoprotein cholesterol level at 30 mg/kg,ip administered once daily for 21 days by automatic biochemical analyzer
Cytotoxicity against golden hamster BSR cells assessed as reduction in cell viability incubated for 24 hrs by microplate luminometer method
Assay data:33 Tested
Cholesterol-lowering activity in Cholesterol fed po dosed hamster assessed as decrease in total cholesterol
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