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Antibacterial activity against Streptomyces coelicolor YF11 assessed as inhibition zone at 10 ug incubated for 2 days by disc diffusion assay
Assay data:2 Tested
SummaryPubMed Citation
Antimicrobial activity against Streptomyces coelicolor A3
Antimicrobial activity against Streptomyces coelicolor A3 in presence of >= 5 uM Ca2+
Inhibition of recombinant Streptomyces coelicolor C-terminal His-tagged GlgEI V279S mutant expressed in Escherichia coli T7 Rosetta cells using MESG as substrate measured every 5 sec for 10 mins by PNP enzyme coupled assay
Assay data:1 Tested
Antibacterial activity against Streptomyces coelicolor M512 assessed as growth inhibition up to 0.5 umol after 48 hrs
Summary
Competitive reversible inhibition of Strepotomyces coelicolor type 2 dehydroquinase expressed in Escherichia coli BL21 (DE3) cells assessed as enone-carboxylate chromophore of 3-dehydroshikimate formation using 3-dehydroquinate as substrate preincubated with enzyme for 3 mins prior to substrate addition by UV spectrophotometric assay
Assay data:8 Active, 7 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Potentiation of chloramphenicol-induced antibacterial activity against Streptomyces coelicolor at 25 ug/mL after 48 hrs relative to MC-207,110
Antibacterial activity against Streptomyces coelicolor after 48 hrs
Assay data:7 Tested
Antibacterial activity against Streptomyces coelicolor overexpressing cmlR2 at 25 ug/mL after 48 hrs
Antibacterial activity against Streptomyces coelicolor overexpressing cmlR1 at 25 ug/mL after 48 hrs
Antibacterial activity against cmlR1 and cmlR2-deficient Streptomyces coelicolor at 25 ug/mL after 48 hrs
Antibacterial activity against cmlR2-deficient Streptomyces coelicolor at 25 ug/mL after 48 hrs
Antibacterial activity against cmlR1-deficient Streptomyces coelicolor at 25 ug/mL after 48 hrs
Inhibition of cmlR2 overexpressed in Streptomyces coelicolor assessed as potentiation of chloramphenicol-induced antibacterial activity measuring reduction in MIC of chloramphenicol at 25 ug/mL after 48 hrs relative to control
Inhibition of cmlR1 overexpressed in Streptomyces coelicolor assessed as potentiation of chloramphenicol-induced antibacterial activity measuring reduction in MIC of chloramphenicol at 25 ug/mL after 48 hrs relative to control
Potentiation of chloramphenicol-induced antibacterial activity against cmlR1 and cmlR2-deficient Streptomyces coelicolor at 25 ug/mL after 48 hrs relative to control
Potentiation of chloramphenicol-induced antibacterial activity against cmlR2-deficient Streptomyces coelicolor at 25 ug/mL after 48 hrs relative to control
Potentiation of chloramphenicol-induced antibacterial activity against cmlR1-deficient Streptomyces coelicolor at 25 ug/mL after 48 hrs relative to control
Antibacterial activity against Streptomyces coelicolor at 25 ug/mL after 48 hrs
Assay data:22 Tested
Potentiation of chloramphenicol-induced antibacterial activity against Streptomyces coelicolor at 25 ug/mL after 48 hrs relative to control
Assay data:10 Active, 18 Tested
SummaryCompounds, ActivePubMed Citation
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