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Inhibition of bacterial MraY
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of beta-lactamase P99 (unknown origin) using cephalosporin nitrocefin as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric analysis
Assay data:1 Tested
SummaryPubMed Citation
Inhibition of TryR (unknown origin)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of TryR (unknown origin) assessed as inhibition constant by FRET assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of TryR (unknown origin) assessed as inhibition constant
Assay data:5 Active, 4 Activity ≤ 1 µM, 6 Tested
Inhibition of bacterial peptide deformylase
Inhibition of Bacterial MraY
Assay data:6 Active, 2 Activity ≤ 1 µM, 9 Tested
Inhibition of bacterial FabH
Assay data:2 Tested
Assay data:1 Active, 1 Activity ≤ 1 µM, 13 Tested
Binding affinity to bacteria OXA-48 assessed as dissociation constant
Assay data:2 Active, 2 Activity ≤ 1 µM, 5 Tested
Binding affinity to bacteria OXA-23/40 assessed as dissociation constant
Binding affinity to bacteria Oxa-23 assessed as dissociation constant
Binding affinity to bacteria PDC-3 assessed as dissociation constant
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Binding affinity to bacteria ADC-7 assessed as dissociation constant
Binding affinity to bacteria KPC-2 assessed as dissociation constant
Inhibition of bacteria ADC-7 assessed as apparent inhibition constant using nitrocefin as substrate
Assay data:3 Active, 5 Tested
Inhibition of bacteria KPC-2 assessed as apparent inhibition constant using nitrocefin as substrate
Assay data:5 Active, 2 Activity ≤ 1 µM, 5 Tested
Inhibition of bacteria OXA-48 assessed as apparent inhibition constant using nitrocefin as substrate
Assay data:1 Active, 1 Activity ≤ 1 µM, 5 Tested
Inhibition of bacteria OXA-23/40 assessed as apparent inhibition constant using nitrocefin as substrate
Assay data:1 Active, 5 Tested
Inhibition of bacteria OXA-23 assessed as apparent inhibition constant using nitrocefin as substrate
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