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The drug is tested on Ruminococcus gnavus strain: ATCC29149 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:260 Tested
SummaryPubMed Citation
Inhibition of Ruminococcus gnavus GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7
Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Ruminococcus gnavus GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.1
Assay data:2 Active, 2 Activity ≤ 1 µM, 6 Tested
Inhibition of Ruminococcus gnavus GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition up to pH 6.9
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Antibacterial activity against Ruminococcus gnavus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam
Assay data:1 Tested
Antibacterial activity against Ruminococcus gnavus by CLSI M11-A6 agar dilution method
Assay data:6 Tested
Antimicrobial activity against Ruminococcus gnavus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam
Antimicrobial activity against Ruminococcus gnavus by Wadsworth agar dilution method
Assay data:4 Tested
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