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Antibacterial activity against Escherichia coli
Assay data:4 Active, 4 Tested
Summary
Inhibition of Escherichia coli OGDHc E1 subunit assessed as inhibition constant preincubated for 60 mins followed by alpha-ketoglutarate addition using 30 uM ThDP as substrate by microplate reader analysis
Assay data:2 Active, 2 Tested
Inhibition of Escherichia coli OGDHc E1 subunit assessed as DCPIP reduction preincubated for 60 mins followed by alpha-ketoglutarate addition using 30 uM ThDP as substrate by microplate reader analysis
Assay data:2 Tested
Inhibition of Escherichia coli ErmC methyltransferase
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Antibacterial activity against wild type Escherichia coli harbouring TolC-deficient mutant with pore
Assay data:5 Active, 4 Activity ≤ 1 µM, 9 Tested
Antibacterial activity against wild type Escherichia coli harbouring TolC-deficient mutant
Assay data:5 Active, 2 Activity ≤ 1 µM, 9 Tested
Antibacterial activity against wild type Escherichia coli harbouring pore
Assay data:1 Active, 9 Tested
Assay data:8 Tested
Antibacterial activity against Escherichia coli BW25113
Assay data:1 Tested
Inhibition of Escherichia coli DNA gyrase ATPase activity using pBR322 as substrate incubated for 10 mins in presence of NADH and ATP by supercoiling assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryRelated BioAssays by Target
Inhibition of ribosome dependent GTPase activity of Escherichia coli LepA
Assay data:1 Active, 1 Tested
Inhibition of ribosome dependent GTPase activity of His-tagged Escherichia coli IF2
Binding affinity to Escherichia coli FMN riboswitch RNA assessed as dissociation constant
Binding affinity to Escherichia coli K12 glutaminyl-tRNA synthetase assessed as inhibition constant
Binding affinity to Escherichia coli K12 Prolyl-tRNA synthetase
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Binding affinity to Escherichia coli methionyl adenylate synthetase
Inhibition of Escherichia coli K12 methionyl tRNA synthetase
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of Escherichia coli RNA polymerase
Inhibition of MraY in Escherichia coli
Assay data:11 Active, 2 Activity ≤ 1 µM, 15 Tested
Inhibition of MraY in Escherichia coli K12
Assay data:8 Active, 5 Activity ≤ 1 µM, 8 Tested
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