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AntiBrugia pahangi activity Average day 3 IC50 (uM)
Assay data:2 Active, 2 Tested
SummaryCompounds, Active
AntiBrugia pahangi activity Average inhibition motility at 10 uM (%)
Assay data:4 Active, 8 Tested
Antifilarial activity against Brugia pahangi infected in gerbils assessed as reduction in worm burden at 5 mg/kg, sid in weekends for 28 days
Assay data:1 Tested
SummaryPubMed Citation
Antifilarial activity against Brugia pahangi infected in gerbils assessed as reduction in worm burden at 5 mg/kg, bid in weekdays for 28 days
anti-filarial Activity was measured against Brugia pahangi in jirds at 100 mg/kg/day(5 days) dose
Macrofilarial reduction at 100 mg/kg dosage by subcutaneous administration for a period of 5 days against Brugia pahangi
Assay data:34 Tested
Compound tested for anti-filarial activity against adult worm of Brugia pahangi in jirds at 100 mg/kg x 5 days administered subcutaneously; No activity
Assay data:25 Tested
In vivo percent reduction of Brugia pahangi worm in gerbils; Toxic
Assay data:2 Tested
In vivo percent reduction of Brugia pahangi worm in gerbils; Some toxicity
In vivo percent reduction of Brugia pahangi worm in gerbils
Assay data:20 Tested
Antifilarial activity against Brugia pahangi in jirds was determined after subcutaneous administration of 100 mg/kg/day.
Antifilarial activity (percent reduction of live Brugia pahangi at necropsy relative to controls) was evaluated at dose of 6.25 mg/kg/day administered subcutaneously
Antifilarial activity (percent reduction of live Brugia pahangi at necropsy relative to controls) was evaluated at dose of 25 mg/kg/day administered subcutaneously
Antifilarial activity (percent reduction of live Brugia pahangi at necropsy relative to controls) was evaluated at dose of 100 mg/kg/day administered subcutaneously
Assay data:13 Tested
Antifilarial activity (percent reduction of live Brugia pahangi at necropsy relative to controls) was evaluated at dose of 1.56 mg/kg/day administered subcutaneously
Antifilarial activity was measured against the adult worms of Brugia pahangi in jirds by subcutaneous administration at a dose of 50 mg/kg/day
Antifilarial activity was measured against the adult worms of Brugia pahangi in jirds by subcutaneous administration at a dose of 250 mg/kg/day
Antifilarial activity was measured against the adult worms of Brugia pahangi in jirds by subcutaneous administration at a dose of 100 mg/kg/day
Antifilarial activity was measured against the adult worms of Brugia pahangi in jirds by subcutaneous administration at a dose of 6.5 mg/kg/day
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