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Anthelmintic activity against fourth stage larvae of Haemonchus contortus assessed as midbody width of L4 larvae measured after 7 days by microscopic analysis (Rvb = 16.3+/-1.5 uM)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Anthelmintic activity against fourth stage larvae of Haemonchus contortus assessed as induction of skinny phenotype measured after 7 days
Assay data:1 Tested
SummaryPubMed Citation
Anthelmintic activity against third stage larvae of Haemonchus contortus assessed as reduction in larval motility measured at 168 hrs by microscope based analysis
Assay data:12 Active, 3 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Anthelmintic activity against Haemonchus contortus assessed as induction of skinny phenotype at 50 uM measured at 168 hrs by microscope based analysis
Assay data:15 Tested
Anthelmintic activity against Haemonchus contortus assessed as inhibition of L4 development at 50 uM measured at 168 hrs by microscope based analysis relative to control
Anthelmintic activity against third stage larvae of Haemonchus contortus assessed as reduction in larval motility at 50 uM measured at 168 hrs by microscope based analysis relative to control
Anthelmintic activity against fourth stage larvae of Haemonchus contortus assessed as induction of skinny phenotype at 100 uM measured after 7 days relative to control
Inhibition of Haemonchus contortus by L4 development assay
Assay data:10 Active, 4 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Anthelmintic activity against third stage larvae of Haemonchus contortus assessed as inhibition of larval development at 20 uM measured after 7 days by microscopic analysis
Assay data:7 Tested
Anthelmintic activity against third stage larvae of Haemonchus contortus assessed as inhibition of xL3 larval motility at 20 uM measured after 72 hrs
Anti-helmintic activity against fourth stage of Haemonchus contortus larvae assessed as reduction in development of L4 stage incubated for 72 hrs followed by reincubation in humidified environment for 4 days
Assay data:6 Active, 2 Activity ≤ 1 µM, 60 Tested
Anti-helmintic activity against third-stage Haemonchus contortus larvae assessed as inhibition of xL3 motility measured after 72 hrs
Assay data:21 Active, 4 Activity ≤ 1 µM, 60 Tested
Anti-helmintic activity against fourth stage L4 Haemonchus contortus larvae assessed as induction of abnormal morphological phenotype at >= 50 uM after 7 days
Anti-helmintic activity against fourth stage L4 Haemonchus contortus larvae assessed as inhibition of larvae motility at 100 uM after 72 hrs
Anti-helmintic activity against third-stage xL3 Haemonchus contortus larvae assessed as inhibition of larvae motility at 100 uM measured after 72 hrs
Assay data:3 Tested
Anti-helmintic activity against third-stage Haemonchus contortus larvae assessed as reduction in development of xL3 stage larvae to L4 stage after 7 days
Anti-helmintic activity against third-stage Haemonchus contortus larvae assessed as reduction in larval motility after 72 hrs
Anti-helmintic activity against fourth stage L4 Haemonchus contortus larvae assessed as induction of changes in internal structure measured on day 7 by light microscopic method
Anti-helmintic activity against fourth stage L4 Haemonchus contortus larvae assessed as induction of eviscerated phenotype measured on day 7 by light microscopic method
Anti-helmintic activity against third-stage Haemonchus contortus larvae assessed as reduction in development of xL3 stage larvae to L4 stage at low concentration after 7 days
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