PubChem BioAssay Links for Taxonomy (Select 9986) - PubChem BioAssay - NCBI

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Select item 19599421.

Binding affinity to AT1 in rabbit aorta

Source:: ChEMBL

Assay data:7 Active, 24 Activity ≤ 1 µM, 24 Tested

AID:: 1959942

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19595532.

Inhibition of SERCA1a in rabbit Sarcoplasmic reticulum assessed as inhibition constant in presence of [gamma-32P]ATP and calcium ionophore A23187 by by coupled enzyme assay

Source:: ChEMBL

Protein Target:: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1959553

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19593713.

Binding affinity to recombinant rabbit FBPase expressed in Escherichia coli assessed as maximal activity

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1959371

Summary Compounds, Active PubMed Citation

Select item 19540274.

Binding affinity to angiotensin-converting enzyme in rabbit lung assessed as inhibition constant

Source:: ChEMBL

Protein Target:: Angiotensin-converting enzyme

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1954027

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19540255.

Inhibition of rabbit lung angiotensin-converting enzyme

Source:: ChEMBL

Protein Target:: Angiotensin-converting enzyme

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1954025

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19526806.

Antiplatelet activity in rabbit platelet rich plasma assessed as inhibition of antigen-antibody-induced platelet aggregation

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1952680

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19526797.

Antiplatelet activity in rabbit platelet rich plasma assessed as inhibition of arachidonic acid-induced platelet aggregation

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1952679

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19526788.

Antiplatelet activity in rabbit platelet rich plasma assessed as inhibition of thrombin-induced platelet aggregation

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1952678

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19526779.

Antiplatelet activity in rabbit platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1952677

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195267610.

Antiplatelet aggregation activity in rabbit platelet rich plasma assessed as reduction in ADP-induced platelet aggregation

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1952676

Summary Compounds, Active PubMed Citation

Select item 194988611.

Inhibition of eIF4E-mediated translation in luciferase RNA primed rabbit reticulocyte lysate assessed as reduction in luciferase production incubated for 90 mins by agarose gel electrophoresis

Source:: ChEMBL

Assay data:1 Active, 23 Tested

AID:: 1949886

Summary Compounds, Active PubMed Citation

Select item 194960712.

Activation of rabbit psoas fast skeletal Myofibril

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1949607

Summary Compounds, Active PubMed Citation

Select item 194628813.

Inhibition of HSP90 in rabbit reticulocyte lysates incubated for 3 hrs by denatured luciferase refolding assay

Source:: ChEMBL

Assay data:13 Active, 5 Activity ≤ 1 µM, 14 Tested

AID:: 1946288

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194320114.

Activation of rabbit sGC assessed as induction of preconstricted aortic ring relaxation

Source:: ChEMBL

Assay data:7 Active, 4 Activity ≤ 1 µM, 7 Tested

AID:: 1943201

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194284815.

Inhibition of ALR2 in rabbit lens using D,L-glyceraldehyde as substrate preincubated for 1 min in presence of NADPH followed by substrate addition and measured after 4 mins by spectrophotometric assay

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1942848

Summary Compounds, Active PubMed Citation

Select item 194075316.

Binding affinity to rabbit albumin assessed as dissociation constant by surface plasmon resonance assay

Source:: ChEMBL

Protein Target:: Albumin

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1940753

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194074017.

Binding affinity to rabbit albumin by fluorescence polarization assay

Source:: ChEMBL

Protein Target:: Albumin

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1940740

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194023518.

Inhibition of rabbit liver microsome SOAT

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1940235

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194022919.

Inhibition of rabbit liver microsome ACAT

Source:: ChEMBL

Assay data:2 Active, 2 Tested

AID:: 1940229

Summary Compounds, Active PubMed Citation

Select item 194021520.

Inhibition of rabbit intestinal microsomal SOAT using [1-14C]oleoyl-CoA as substrate by scintillation counting analysis

Source:: ChEMBL

Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested

AID:: 1940215

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

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Target

Proteins (2)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (308)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (15)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (147)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (287)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (960)
BioAssays extracted from the literature
Other (40)
BioAssays deposited by other experimentalists

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PubChem BioAssay Links for Taxonomy (Select 9986) (1000)
PubChem BioAssay
Nucleotide Links for Gene (Select 3480) (52)
Nucleotide
OMIM Links for Gene (Select 8360) (1)
OMIM
Homo sapiens TYRO3 protein tyrosine kinase (TYRO3), transcript variant 1, mRNA
Homo sapiens TYRO3 protein tyrosine kinase (TYRO3), transcript variant 1, mRNA
gi|1519245739|ref|NM_006293.4|

Nucleotide
ribosome maturation factor RimP [Campylobacter jejuni]
ribosome maturation factor RimP [Campylobacter jejuni]
gi|2518278675|gb|KAJ9818304.1||gnl| DHQ|QR412_00050

Protein

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