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qHTS for compounds that reverse cellular toxicity of Amyloid beta (A-beta) peptide in yeast: LOPAC Validation Assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 1277 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS of alpha-syn Inhibitors
Assay data:503 Active, 131 Activity ≤ 1 µM, 370177 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS of TDP-43 Inhibitors
Assay data:7165 Active, 4 Activity ≤ 1 nM, 2170 Activity ≤ 1 µM, 406923 Tested
In vivo-based yeast HTS counterscreen to detect compounds rescuing yeast growth/survival of Saccharomyces cerevisiae SKN7-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-02_Inhibitor_Dose_CherryPick_Activity
Assay data:351 Active, 54 Activity ≤ 1 µM, 828 Tested
Dose Response with BCECF Assay for V-ATPase inhibitors that increase vacuolar pH, Powder Set 1
Assay data:7 Active, 4 Activity ≤ 1 µM, 26 Tested
Confirmation dose response of additional hit compounds from high-throughput yeast screen for caloric restriction mimetics that inhibit age-related superoxide.
Assay data:29 Active, 12 Activity ≤ 1 µM, 74 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Confirmation dose response of powder sourced compounds for HTS of caloric restriction mimetics that inhibit age-related superoxide.
Assay data:22 Active, 6 Activity ≤ 1 µM, 73 Tested
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically RPL19A
Assay data:3 Active, 1 Activity ≤ 1 µM, 41 Tested
Confirmatory Primary Screen Hits KU SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically RPL19A
Assay data:42 Active, 5 Activity ≤ 1 µM, 113 Tested
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
Assay data:101 Active, 5 Activity ≤ 1 µM, 613 Tested
Ras-converting Enzyme/Cell Proliferation Pathway Measured in Biochemical System Using Plate Reader - 2034-01_Inhibitor_Dose_CherryPick
Assay data:278 Active, 18 Activity ≤ 1 µM, 716 Tested
Fluorescence Biochemical Dose Confirmation to Identify Inhibitors of Yeast HDACs
Assay data:2 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 46 Tested
qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion
Assay data:739 Active, 1 Activity ≤ 1 nM, 177 Activity ≤ 1 µM, 322909 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Luminescence Whole-Organism Dose Retest to Confirm Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301
Assay data:224 Active, 9 Activity ≤ 1 µM, 2298 Tested
Confirmation dose response of hits from high-throughput yeast screen for caloric restriction mimetics that inhibit age-related superoxide
Assay data:24 Active, 9 Activity ≤ 1 µM, 46 Tested
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits
Assay data:205 Active, 14 Activity ≤ 1 µM, 613 Tested
qHTS Assay for Inhibitors of Influenza NS1 Protein Function
Assay data:1073 Active, 1682 Activity ≤ 1 µM, 270314 Tested
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