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Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltransferases
Assay data:968 Active, 24930 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Confirmatory Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltransferases
Assay data:902 Active, 1111 Tested
TTK Enzyme Assay from US Patent US11884671: "Purinone compounds and their use in treating cancer"
Assay data:46 Active, 22 Activity ≤ 1 µM, 51 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
HPK1 Kinase Assay (Biochemical Assay) from US Patent US20240025922: "TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS"
Assay data:181 Active, 187 Activity ≤ 1 µM, 187 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
In Vitro DGKα and DGKζ Inhibition Assay from US Patent US20240025900: "TETRACYCLIC COMPOUNDS AS DGK INHIBITORS"
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Biochemical Assay from US Patent US20240025884: "COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF"
Assay data:498 Active, 503 Activity ≤ 1 µM, 503 Tested
HTRF Assay from US Patent US20240018153: "BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF"
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Assay data:10 Active, 10 Activity ≤ 1 µM, 10 Tested
Assay data:11 Active, 11 Activity ≤ 1 µM, 11 Tested
ADP-GLO Kinase Assay from US Patent US20240018151: "NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME"
Assay data:8 Active, 10 Activity ≤ 1 µM, 10 Tested
UDP-Glo Glucosylceramide Synthase Biochemical Assay from US Patent US20240018140: "MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS"
Assay data:83 Active, 14 Activity ≤ 1 nM, 83 Activity ≤ 1 µM, 83 Tested
Biochemical Assay from US Patent US20240016810: "COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS"
Assay data:21 Active, 1 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 26 Tested
A2A Tag-lite HTRF Assay from US Patent US11873304: "Fused pyrimidine derivatives as A2A/A2B inhibitors"
Assay data:34 Active, 34 Activity ≤ 1 µM, 34 Tested
Biochemical Activity ACSS2 Assay from US Patent US20240009175: "TETRAZOLE DERIVATIVES"
Assay data:51 Active, 7 Activity ≤ 1 nM, 50 Activity ≤ 1 µM, 51 Tested
HEK Reporter Assay from US Patent US20240042050: "ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF"
Assay data:16 Active, 12 Activity ≤ 1 µM, 16 Tested
FLIPR Assay from US Patent US11891403: "Tetrazole derivatives as TRPA1 inhibitors"
Assay data:24 Active, 24 Activity ≤ 1 µM, 24 Tested
[35S]-GTPgammaS binding assay from US Patent US20240050427: "TREATMENTS FOR OBSESSIVE COMPULSIVE DISORDER"
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
ASK1 Enzyme Assay from US Patent US11897898: "Pyridine macrocycle compounds as ASK1 inhibiting agents"
Assay data:34 Active, 30 Activity ≤ 1 µM, 35 Tested
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