txid9606[Organism:exp] AND (pcassay_pccompound_active[filt]) AND (pcas - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Search results

Items: 1 to 20 of 8127

<< First< Prev

Page of 407

Select item 19154041.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000587a GABRA1

Source:: ChEMBL

Protein Target:: Gamma-aminobutyric acid receptor subunit alpha-1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1915404

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19154032.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000587a DRD4

Source:: ChEMBL

Protein Target:: D(4) dopamine receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1915403

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19154023.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000302b GABRA1

Source:: ChEMBL

Protein Target:: Gamma-aminobutyric acid receptor subunit alpha-1

Assay data:1 Active, 1 Tested

AID:: 1915402

Summary Compounds, Active Related BioAssays by Target

Select item 19133614.

Affinity Biochemical interaction (PPiLight Biochemical Assay (full-length human NUDT1)) EUB0000302b NUDT1

Source:: ChEMBL

Protein Target:: 7,8-dihydro-8-oxoguanine triphosphatase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913361

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19130495.

Affinity On-target Cellular interaction (CETSA (cellular thermal shift assay in K562 cells)) EUB0000302b NUDT1

Source:: ChEMBL

Protein Target:: 7,8-dihydro-8-oxoguanine triphosphatase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913049

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19124716.

Substrate uptake and inhibition of the Vesicular Amine Transporter 2 (VMAT2, SLC18A2) as assessed by uptake of a fluorescent substrate (FFN206) in HEK-293 JumpIN-SLC18A2 cells (PubChem AID: 1794817)

Source:: ChEMBL

Protein Target:: Synaptic vesicular amine transporter

Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested

AID:: 1912471

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19124487.

Substrate uptake and inhibition of the chromaffin granule amine transporter (VAT1, VMAT1, SLC18A1) as assessed by uptake of a fluorescent substrate (FFN206) in HEK-293 JumpIN-SLC18A1 cells (PubChem AID: 1794818)

Source:: ChEMBL

Protein Target:: Chromaffin granule amine transporter

Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1912448

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19124478.

Inhibition of the equilibrative nucleoside transporter (ENT1, SLC29A1) as assessed by GPCR-mediated changes in cell morphology using the impedance-based transporter activity through receptor activation (TRACT) assay (PubChem AID: 1745861)

Source:: ChEMBL

Protein Target:: Equilibrative nucleoside transporter 1

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 5 Tested

AID:: 1912447

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18451369.

Eurofins cellular functional assay - Antagonist (EDNRB)

Source:: ChEMBL

Protein Target:: Endothelin receptor type B

Assay data:1 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1845136

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183541710.

BUB1 biochemical assay (low ATP)

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1835417

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183540511.

Competitive fluorescence polarization binding assay (FKBP5)

Source:: ChEMBL

Protein Target:: Peptidyl-prolyl cis-trans isomerase FKBP5

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1835405

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183538912.

SMOX CETSA assay

Source:: ChEMBL

Protein Target:: Spermine oxidase

Assay data:1 Active, 1 Tested

AID:: 1835389

Summary Compounds, Active Related BioAssays by Target

Select item 183538713.

HyPerBlu SMOX enzymatic assay

Source:: ChEMBL

Protein Target:: Spermine oxidase

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1835387

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183522514.

Source:: ChEMBL

Protein Target:: B-cell lymphoma 6 protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1835225

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183485115.

BRET whole cell binding assay

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1834851

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183473116.

Source:: ChEMBL

Protein Target:: Histamine H4 receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1834731

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183461117.

FLIPR functional assay (Ca influx activity of CHO cells)

Source:: ChEMBL

Protein Target:: Free fatty acid receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1834611

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183461018.

FFAR1 binding assay

Source:: ChEMBL

Protein Target:: Free fatty acid receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1834610

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183452819.

GluN2A-containing NMDA receptor (Ca2+ influx) assay (EC50)

Source:: ChEMBL

Protein Target:: Glutamate receptor ionotropic, NMDA 2A

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1834528

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183445820.

Cellular target engagement assay with: SRPK3

Source:: ChEMBL

Protein Target:: SRSF protein kinase 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1834458

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

<< First< Prev

Page of 407

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (249)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (8,127)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (778)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (4,980)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (54)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (5,790)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (42)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (128)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Other (8,127)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Search details

Recent activity

Clear Turn Off Turn On

txid9606[Organism:exp] AND (pcassay_pccompound_active[filt]) AND ... (8127)
txid9606[Organism:exp] AND (pcassay_pccompound_active[filt]) AND (pcassay_pcassay_otherexperimentalists[filt])
Search

PubChem BioAssay

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay