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Select item 86909891.

Adaptation of mammals to hypoxia

Fang Li, Zhenglei Qiao, Qijiao Duan, Eviatar Nevo

Animal Model Exp Med. 2021 Dec; 4(4): 311–318. Published online 2021 Nov 29. doi: 10.1002/ame2.12189

PMCID:: PMC8690989

Abstract Article PDF–1.1M

Select item 77687582.

Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation

Kexin Li, Shangzhe Zhang, Xiaoying Song, Alexandra Weyrich, Yinjia Wang, Xi Liu, Na Wan, Jianquan Liu, Matěj Lövy, Haihong Cui, Vladimir Frenkel, Avi Titievsky, Julia Panov, Leonid Brodsky, Eviatar Nevo

Proc Natl Acad Sci U S A. 2020 Dec 22; 117(51): 32499–32508. Published online 2020 Dec 4. doi: 10.1073/pnas.2018123117

PMCID:: PMC7768758

Abstract Article PDF–3.5M

Select item 55133463.

Peto’s Paradox: how has evolution solved the problem of cancer prevention?

Marc Tollis, Amy M. Boddy, Carlo C. Maley

BMC Biol. 2017; 15: 60. Published online 2017 Jul 13. doi: 10.1186/s12915-017-0401-7

PMCID:: PMC5513346

Abstract Article PDF–381K

Select item 54609534.

Sequence Analysis and Phylogenetic Studies of Hypoxia-Inducible Factor-1α

Jagadeesha Poyya, Chandrashekhar G Joshi, D Jagadeesha Kumar, HG Nagendra

Cancer Inform. 2017; 16: 1176935117712242. Published online 2017 May 31. doi: 10.1177/1176935117712242

PMCID:: PMC5460953

Abstract Article PDF–3.0M

Select item 47764585.

Adaptive methylation regulation of p53 pathway in sympatric speciation of blind mole rats, Spalax

Yang Zhao, Jia-Wei Tang, Zhi Yang, Yi-Bin Cao, Ji-Long Ren, Yuval Ben-Abu, Kexin Li, Xue-Qun Chen, Ji-Zeng Du, Eviatar Nevo

Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8): 2146–2151. Published online 2016 Feb 8. doi: 10.1073/pnas.1522658112

PMCID:: PMC4776458

Abstract Article PDF–1.0M

Select item 35749026.

Possible incipient sympatric ecological speciation in blind mole rats (Spalax)

Yarin Hadid, Shay Tzur, Tomáš Pavlíček, Radim Šumbera, Jan Šklíba, Matěj Lövy, Ori Fragman-Sapir, Avigdor Beiles, Ran Arieli, Shmuel Raz, Eviatar Nevo

Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7): 2587–2592. Published online 2013 Jan 28. doi: 10.1073/pnas.1222588110

PMCID:: PMC3574902

Abstract Article PDF–469K

Select item 43995597.

Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity

Yael H Edrey, Diana Casper, Dorothee Huchon, James Mele, Jonathan A Gelfond, Deborah M Kristan, Eviatar Nevo, Rochelle Buffenstein

Aging Cell. Author manuscript; available in PMC 2015 Apr 16.

Published in final edited form as: Aging Cell. 2012 Apr; 11(2): 213–222. Published online 2011 Dec 29. doi: 10.1111/j.1474-9726.2011.00772.x

PMCID:: PMC4399559

Abstract Article PDF–2.0M

Select item 30030358.

Neuroglobin, cytoglobin, and myoglobin contribute to hypoxia adaptation of the subterranean mole rat Spalax

Aaron Avivi, Frank Gerlach, Alma Joel, Stefan Reuss, Thorsten Burmester, Eviatar Nevo, Thomas Hankeln

Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50): 21570–21575. Published online 2010 Nov 29. doi: 10.1073/pnas.1015379107

PMCID:: PMC3003035

Abstract Article PDF–773K

Select item 26396989.

Lipid Profile and Serum Characteristics of the Blind Subterranean Mole Rat, Spalax

Nicola J. Nasser, Marielle Kaplan, Eviatar Nevo, Michael Aviram

PLoS One. 2009; 4(2): e4528. Published online 2009 Feb 20. doi: 10.1371/journal.pone.0004528

PMCID:: PMC2639698

Abstract Article PDF–329K

Select item 263505110.

Molecular Structure of Heparan Sulfate from Spalax: IMPLICATIONS OF HEPARANASE AND HYPOXIA

Elina Sandwall, Sabrina Bodevin, Nicola J. Nasser, Eviatar Nevo, Aaron Avivi, Israel Vlodavsky, Jin-Ping Li

J Biol Chem. 2009 Feb 6; 284(6): 3814–3822. doi: 10.1074/jbc.M802196200

PMCID:: PMC2635051

Abstract Article PDF–795K

Select item 265014111.

Alternatively spliced Spalax heparanase inhibits extracellular matrix degradation, tumor growth, and metastasis

Nicola J. Nasser, Aaron Avivi, Itay Shafat, Evgeny Edovitsky, Eyal Zcharia, Neta Ilan, Israel Vlodavsky, Eviatar Nevo

Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7): 2253–2258. Published online 2009 Jan 21. doi: 10.1073/pnas.0812846106

PMCID:: PMC2650141

Abstract Article PDF–844K

Select item 128797912.

Evolutionary regulation of the blind subterranean mole rat, Spalax, revealed by genome-wide gene expression

L. I. Brodsky, J. Jacob-Hirsch, A. Avivi, L. Trakhtenbrot, S. Zeligson, N. Amariglio, A. Paz, A. B. Korol, M. Band, G. Rechavi, E. Nevo

Proc Natl Acad Sci U S A. 2005 Nov 22; 102(47): 17047–17052. Published online 2005 Nov 14. doi: 10.1073/pnas.0505043102

PMCID:: PMC1287979

Abstract Article PDF–370K

Select item 125772313.

Adaptive evolution of heparanase in hypoxia-tolerant Spalax: Gene cloning and identification of a unique splice variant

Nicola J. Nasser, Eviatar Nevo, Itay Shafat, Neta Ilan, Israel Vlodavsky, Aaron Avivi

Proc Natl Acad Sci U S A. 2005 Oct 18; 102(42): 15161–15166. Published online 2005 Oct 4. doi: 10.1073/pnas.0507279102

PMCID:: PMC1257723

Abstract Article PDF–590K

Select item 51446214.

Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation

Osnat Ashur-Fabian, Aaron Avivi, Luba Trakhtenbrot, Konstantin Adamsky, Meytal Cohen, Gadi Kajakaro, Alma Joel, Ninette Amariglio, Eviatar Nevo, Gideon Rechavi

Proc Natl Acad Sci U S A. 2004 Aug 17; 101(33): 12236–12241. Published online 2004 Aug 9. doi: 10.1073/pnas.0404998101