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Select item 110782641.

Tip Your Cap for Ebola Virus Neutralization

Sonja M. Best, Heinz Feldmann

Immunity. Author manuscript; available in PMC 2024 May 8.

Published in final edited form as: Immunity. 2018 Aug 21; 49(2): 204–206. doi: 10.1016/j.immuni.2018.08.001

PMCID:: PMC11078264

Abstract Article PDF–144K

Select item 110751172.

Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism

Yoshihiro Takadate, Tatsunari Kondoh, Manabu Igarashi, Junki Maruyama, Rashid Manzoor, Hirohito Ogawa, Masahiro Kajihara, Wakako Furuyama, Masahiro Sato, Hiroko Miyamoto, Reiko Yoshida, Terence E. Hill, Alexander N. Freiberg, Heinz Feldmann, Andrea Marzi, Ayato Takada

Cell Rep. Author manuscript; available in PMC 2024 May 7.

Published in final edited form as: Cell Rep. 2020 Jan 14; 30(2): 308–319.e5. doi: 10.1016/j.celrep.2019.12.042

PMCID:: PMC11075117

Abstract Article PDF–1.7M

Select item 110751163.

A biaryl sulfonamide derivative as a novel inhibitor of filovirus infection

Mao Isono, Wakako Furuyama, Makoto Kuroda, Tatsunari Kondoh, Manabu Igarashi, Masahiro Kajihara, Reiko Yoshida, Rashid Manzoor, Kosuke Okuya, Hiroko Miyamoto, Heinz Feldmann, Andrea Marzi, Masahiro Sakaitani, Asuka Nanbo, Ayato Takada

Antiviral Res. Author manuscript; available in PMC 2024 May 7.

Published in final edited form as: Antiviral Res. 2020 Nov; 183: 104932. Published online 2020 Sep 15. doi: 10.1016/j.antiviral.2020.104932

PMCID:: PMC11075116

Abstract Article PDF–1.6M

Select item 110592094.

Ebola: Lessons on Vaccine Development

Heinz Feldmann, Friederike Feldmann, Andrea Marzi

Annu Rev Microbiol. Author manuscript; available in PMC 2024 Apr 29.

Published in final edited form as: Annu Rev Microbiol. 2018 Sep 8; 72: 423–446. doi: 10.1146/annurev-micro-090817-062414

PMCID:: PMC11059209

Abstract Article PDF–686K

Select item 110490465.

Identification and Potential Roles of Human MicroRNAs in Ebola Virus Infection and Disease Pathogenesis

Melvin Mensah-Bonsu, Christopher Doss, Clay Gloster, Perpetua Muganda

Genes (Basel) 2024 Apr; 15(4): 403. Published online 2024 Mar 25. doi: 10.3390/genes15040403

PMCID:: PMC11049046

Abstract Article PDF–10M

Select item 110146856.

Reverse genetics systems as tools for the development of novel therapies against filoviruses

Thomas Hoenen, Heinz Feldmann

Expert Rev Anti Infect Ther. Author manuscript; available in PMC 2024 Apr 12.

Published in final edited form as: Expert Rev Anti Infect Ther. 2014 Oct; 12(10): 1253–1263. Published online 2014 Aug 28. doi: 10.1586/14787210.2014.948848

PMCID:: PMC11014685

Abstract Article PDF–714K

Select item 110061147.

Immunogenicity and Vaccine Shedding After 1 or 2 Doses of rVSVΔG-ZEBOV-GP Ebola Vaccine (ERVEBO®): Results From a Phase 2, Randomized, Placebo-controlled Trial in Children and Adults

Andrew W Lee, Ken Liu, Edouard Lhomme, Julie Blie, John McCullough, Matthew T Onorato, Laurie Connor, Jakub K Simon, Sheri Dubey, Susan VanRheenen, Jonathan Deutsch, Abigail Owens, Amy Morgan, Carolee Welebob, Donna Hyatt, Sunita Nair, Benjamin Hamzé, Oumar Guindo, Samba O Sow, Abdoul H Beavogui, Bailah Leigh, Mohamed Samai, Pauline Akoo, Alimamy Serry-Bangura, Suzanne Fleck, Fatou Secka, Brett Lowe, Deborah Watson-Jones, Céline Roy, Lisa E Hensley, Mark Kieh, Beth-Ann G Coller, the PREVAC Study Team

Clin Infect Dis. 2024 Apr 15; 78(4): 870–879. Published online 2023 Nov 15. doi: 10.1093/cid/ciad693

PMCID:: PMC11006114

Abstract Article PDF–687K

Select item 109778308.

Ten Years of High-Consequence Pathogens—Research Gains, Readiness Gaps, and Future Goals

Jennifer H. McQuiston, Joel M. Montgomery, Christina L. Hutson

Emerg Infect Dis. 2024 Apr; 30(4): 800–802. doi: 10.3201/eid3004.240160

PMCID:: PMC10977830

Article PDF–238K

Select item 109807459.

Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials

Myra Happe, Amelia R. Hofstetter, Jing Wang, Galina V. Yamshchikov, LaSonji A. Holman, Laura Novik, Larisa Strom, Francis Kiweewa, Salim Wakabi, Monica Millard, Colleen F. Kelley, Sarah Kabbani, Srilatha Edupuganti, Allison Beck, Florence Kaltovich, Tamar Murray, Susanna Tsukerman, Derick Carr, Carl Ashman, Daphne A. Stanley, Aurélie Ploquin, Robert T. Bailer, Richard Schwartz, Fatim Cham, Allan Tindikahwa, Zonghui Hu, Ingelise J. Gordon, Nadine Rouphael, Katherine V. Houser, Emily E. Coates, Barney S. Graham, Richard A. Koup, John R. Mascola, Nancy J. Sullivan, Merlin L. Robb, Julie A. Ake, Kirsten E. Lyke, Mark J. Mulligan, Julie E. Ledgerwood, Hannah Kibuuka, the VRC 208 and RV 422 study team

NPJ Vaccines. 2024; 9: 67. Published online 2024 Mar 29. doi: 10.1038/s41541-024-00833-z

PMCID:: PMC10980745

Abstract Article PDF–3.0M

Select item 1094225810.

Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication

Carlos A. Rodríguez-Salazar, Sarah van Tol, Olivier Mailhot, Maria Gonzalez-Orozco, Gabriel T. Galdino, Abbey N. Warren, Natalia Teruel, Padmanava Behera, Kazi Sabrina Afreen, Lihong Zhang, Terry L. Juelich, Jennifer K. Smith, María Inés Zylber, Alexander N. Freiberg, Rafael J. Najmanovich, Maria I. Giraldo, Ricardo Rajsbaum

PLoS Biol. 2024 Feb; 22(2): e3002544. Published online 2024 Feb 29. doi: 10.1371/journal.pbio.3002544

PMCID:: PMC10942258

Abstract Article PDF–2.2M

Select item 1089248211.

Long-Term Clinical Safety of the Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccines: A Prospective, Multi-Country, Observational Study

Adeep Puri, Andrew J. Pollard, Catherine Schmidt-Mutter, Fabrice Lainé, George PrayGod, Hannah Kibuuka, Houreratou Barry, Jean-François Nicolas, Jean-Daniel Lelièvre, Sodiomon Bienvenu Sirima, Beatrice Kamala, Daniela Manno, Deborah Watson-Jones, Auguste Gaddah, Babajide Keshinro, Kerstin Luhn, Cynthia Robinson, Macaya Douoguih

Vaccines (Basel) 2024 Feb; 12(2): 210. Published online 2024 Feb 17. doi: 10.3390/vaccines12020210

PMCID:: PMC10892482

Abstract Article PDF–271K

Select item 1087703512.

Transgene expression knock-down in recombinant Modified Vaccinia virus Ankara vectors improves genetic stability and sustained transgene maintenance across multiple passages

Patrick Neckermann, Madlen Mohr, Martina Billmeier, Alexander Karlas, Ditte R. Boilesen, Christian Thirion, Peter J. Holst, Ingo Jordan, Volker Sandig, Benedikt Asbach, Ralf Wagner

Front Immunol. 2024; 15: 1338492. Published online 2024 Feb 6. doi: 10.3389/fimmu.2024.1338492

PMCID:: PMC10877035

Abstract Article PDF–6.4M

Select item 1082823413.

Navigating the Complex Landscape of Ebola Infection Treatment: A Review of Emerging Pharmacological Approaches

Francisca Almeida-Pinto, Rui Pinto, João Rocha

Infect Dis Ther. 2024 Jan; 13(1): 21–55. Published online 2024 Jan 19. doi: 10.1007/s40121-023-00913-y

PMCID:: PMC10828234

Abstract Article PDF–2.3M

Select item 1081315914.

Could SARS-CoV-1 Vaccines in the Pipeline Have Contributed to Fighting the COVID-19 Pandemic? Lessons for the Next Coronavirus Plague

Daniel López, Marina García-Peydró

Biomedicines. 2024 Jan; 12(1): 62. Published online 2023 Dec 27. doi: 10.3390/biomedicines12010062

PMCID:: PMC10813159

Abstract Article PDF–212K

Select item 1080967115.

The temporal association of CapZ with early endosomes regulates endosomal trafficking and viral entry into host cells

Huazhang Zhu, Dawei Wang, Zuodong Ye, Lihong Huang, Wenjie Wei, Kui Ming Chan, Rongxin Zhang, Liang Zhang, Jianbo Yue

BMC Biol. 2024; 22: 12. Published online 2024 Jan 25. doi: 10.1186/s12915-024-01819-y

PMCID:: PMC10809671

Abstract Article PDF–9.1M

Select item 1078665316.

Ebola virus VP35 perturbs type I interferon signaling to facilitate viral replication

Zengguo Cao, Chenchen Liu, Cheng Peng, Yong Ran, Yulin Yao, Gengfu Xiao, Entao Li, Zixi Chen, Xia Chuai, Sandra Chiu

Virol Sin. 2023 Dec; 38(6): 922–930. Published online 2023 Oct 13. doi: 10.1016/j.virs.2023.10.004

PMCID:: PMC10786653

Abstract Article PDF–2.3M

Select item 1077532017.

Human movement and transmission dynamics early in Ebola outbreaks

Alexandria Gonzalez, Behnam Nikparvar, M. Jeremiah Matson, Stephanie N. Seifert, Heather D. Ross, Vincent Munster, Nita Bharti

Version 1. medRxiv. Preprint. 2023 Dec 19. doi: 10.1101/2023.12.18.23300175

PMCID:: PMC10775320

Abstract Article PDF–2.4M

Select item 1077364318.

RNA binding motif 4 inhibits the replication of ebolavirus by directly targeting 3′-leader region of genomic RNA

Linjin Fan, Yulong Wang, Hongxin Huang, Zequn Wang, Chudan Liang, Xiaofeng Yang, Pengfei Ye, Jingyan Lin, Wendi Shi, Yuandong Zhou, Huijun Yan, Zhenyu Long, Zhongyi Wang, Linna Liu, Jun Qian

Emerg Microbes Infect. 2024; 13(1): 2300762. Published online 2024 Jan 2. doi: 10.1080/22221751.2023.2300762

PMCID:: PMC10773643

Abstract Article PDF–3.1M

Select item 1076005919.

Efficient and accurate detection of viral sequences at single-cell resolution reveals putative novel viruses perturbing host gene expression

Laura Luebbert, Delaney K. Sullivan, Maria Carilli, Kristján Eldjárn Hjörleifsson, Alexander Viloria Winnett, Tara Chari, Lior Pachter

Version 2. bioRxiv. Preprint. 2023 Dec 12 [revised 2024 May 4]. doi: 10.1101/2023.12.11.571168

PMCID:: PMC10760059

Abstract Article PDF–11M

Select item 1075921220.

Natural history of Ebola virus disease in rhesus monkeys shows viral variant emergence dynamics and tissue-specific host responses

Erica Normandin, Sergio Triana, Siddharth S. Raju, Tammy C.T. Lan, Kim Lagerborg, Melissa Rudy, Gordon C. Adams, Katherine C. DeRuff, James Logue, David Liu, Daniel Strebinger, Arya Rao, Katelyn S. Messer, Molly Sacks, Ricky D. Adams, Krisztina Janosko, Dylan Kotliar, Rickey Shah, Ian Crozier, John L. Rinn, Marta Melé, Anna N. Honko, Feng Zhang, Mehrtash Babadi, Jeremy Luban, Richard S. Bennett, Alex K. Shalek, Nikolaos Barkas, Aaron E. Lin, Lisa E. Hensley, Pardis C. Sabeti, Katherine J. Siddle

Cell Genom. 2023 Dec 13; 3(12): 100440. Published online 2023 Nov 21. doi: 10.1016/j.xgen.2023.100440

PMCID:: PMC10759212

Abstract Article PDF–5.8M

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txid186538[Organism:noexp] (1346)
PMC
Aeromonas sp. QDB18 NODE_68_length_21377_cov_150.029108, whole genome shotgun se...
Aeromonas sp. QDB18 NODE_68_length_21377_cov_150.029108, whole genome shotgun sequence
gi|2428034705|ref|NZ_JAPDBQ01000006 gnl|WGS:NZ_JAPDBQ01|NODE_68_length_21377_cov_150.029108

Nucleotide
SHLD2P1 shieldin complex subunit 2 pseudogene 1 [Homo sapiens]
SHLD2P1 shieldin complex subunit 2 pseudogene 1 [Homo sapiens]
Gene ID:414241

Gene
MULTISPECIES: YgiW/YdeI family stress tolerance OB fold protein [Aeromonas]
MULTISPECIES: YgiW/YdeI family stress tolerance OB fold protein [Aeromonas]
gi|743523340|ref|WP_039040598.1|

Protein
MULTISPECIES: cysteine hydrolase family protein [Aeromonas]
MULTISPECIES: cysteine hydrolase family protein [Aeromonas]
gi|1801174851|ref|WP_160837068.1|

Protein

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