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Select item 110895041.

Identification of Potent and Selective Inhibitors of Acanthamoeba: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target

Tatiana Y. Hargrove, David C. Lamb, Zdzislaw Wawrzak, Marcus Hull, Steven L. Kelly, F. Peter Guengerich, Galina I. Lepesheva

J Med Chem. 2024 May 9; 67(9): 7443–7457. Published online 2024 Apr 29. doi: 10.1021/acs.jmedchem.4c00303

PMCID:: PMC11089504

Abstract Article PDF–11M

Select item 110434232.

Kalium channelrhodopsins effectively inhibit neurons

Stanislav Ott, Sangyu Xu, Nicole Lee, Ivan Hong, Jonathan Anns, Danesha Devini Suresh, Zhiyi Zhang, Xianyuan Zhang, Raihanah Harion, Weiying Ye, Vaishnavi Chandramouli, Suresh Jesuthasan, Yasunori Saheki, Adam Claridge-Chang

Nat Commun. 2024; 15: 3480. Published online 2024 Apr 24. doi: 10.1038/s41467-024-47203-w

Correction in:: Nat Commun. 2024; 15: 6088.

PMCID:: PMC11043423

Abstract Article PDF–25M

Select item 110483553.

Screening of Microalgae for Bioactivity with Antiviral, Antibacterial, Anti-Inflammatory and Anti-Cancer Assays

Jorge Hernández-Urcera, Alejandro Romero, Pedro Cruz, Vitor Vasconcelos, Antonio Figueras, Beatriz Novoa, Francisco Rodríguez

Biology (Basel) 2024 Apr; 13(4): 255. Published online 2024 Apr 12. doi: 10.3390/biology13040255

PMCID:: PMC11048355

Abstract Article PDF–3.3M

Select item 110517724.

Prevalence and Preferred Niche of Small Eukaryotes with Mixotrophic Potentials in the Global Ocean

Kaiyi Dong, Ying Wang, Wenjing Zhang, Qian Li

Microorganisms. 2024 Apr; 12(4): 750. Published online 2024 Apr 8. doi: 10.3390/microorganisms12040750

PMCID:: PMC11051772

Abstract Article PDF–4.1M

Select item 109609555.

Isolation of a widespread giant virus implicated in cryptophyte bloom collapse

Helena H Vieira, Paul-Adrian Bulzu, Vojtěch Kasalický, Markus Haber, Petr Znachor, Kasia Piwosz, Rohit Ghai

ISME J. 2024 Jan; 18(1): wrae029. Published online 2024 Feb 24. doi: 10.1093/ismejo/wrae029

PMCID:: PMC10960955

Abstract Article PDF–758K

Select item 109393956.

Temporal and spatial variability of constitutive mixotroph abundance and proportion

Marcella Dobbertin da Costa, Rebecca J Gast, Nicole C Millette

FEMS Microbiol Ecol. 2024 Mar; 100(3): fiae015. Published online 2024 Feb 2. doi: 10.1093/femsec/fiae015

PMCID:: PMC10939395

Abstract Article PDF–1.4M

Select item 108136177.

Effects of Aquatic Plant Coverage on Diversity and Resource Use Efficiency of Phytoplankton in Urban Wetlands: A Case Study in Jinan, China

Hongjingzheng Jiang, Aoran Lu, Jiaxin Li, Mengdi Ma, Ge Meng, Qi Chen, Gang Liu, Xuwang Yin

Biology (Basel) 2024 Jan; 13(1): 44. Published online 2024 Jan 14. doi: 10.3390/biology13010044

PMCID:: PMC10813617

Abstract Article PDF–2.1M

Select item 109804148.

Design and assembly of the 117-kb Phaeodactylum tricornutum chloroplast genome

Emma J L Walker, Mark Pampuch, Nelson Chang, Ryan R Cochrane, Bogumil J Karas

Plant Physiol. 2024 Apr; 194(4): 2217–2228. Published online 2023 Dec 19. doi: 10.1093/plphys/kiad670

PMCID:: PMC10980414

Abstract Article PDF–920K

Select item 107393349.

Circadian rhythms and circadian clock gene homologs of complex alga Chromera velia

Jitka Richtová, Olga Bazalová, Aleš Horák, Aleš Tomčala, Vijaya Geetha Gonepogu, Miroslav Oborník, David Doležel

Front Plant Sci. 2023; 14: 1226027. Published online 2023 Dec 8. doi: 10.3389/fpls.2023.1226027

PMCID:: PMC10739334

Abstract Article PDF–3.1M

Select item 1073063110.

Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES

Barbora Schwarzová, Tim Stüdemann, Muhammed Sönmez, Judith Rössinger, Bangfen Pan, Thomas Eschenhagen, Justus Stenzig, J. Simon Wiegert, Torsten Christ, Florian Weinberger

Pflugers Arch. 2023; 475(12): 1463–1477. Published online 2023 Oct 21. doi: 10.1007/s00424-023-02869-x

PMCID:: PMC10730631

Abstract Article PDF–7.1M

Select item 1063797711.

The preferential transport of NO₃⁻ by full-length Guillardia theta anion channelrhodopsin 1 is enhanced by its extended cytoplasmic domain

Yuya Ohki, Tsukasa Shinone, Sayo Inoko, Miu Sudo, Makoto Demura, Takashi Kikukawa, Takashi Tsukamoto

J Biol Chem. 2023 Nov; 299(11): 105305. Published online 2023 Sep 29. doi: 10.1016/j.jbc.2023.105305

PMCID:: PMC10637977

Abstract Article PDF–3.2M

Select item 1059834612.

Isospectral intermediates in the photochemical reaction cycle of anion channelrhodopsin GtACR1

Pamela Schleissner, Istvan Szundi, Eefei Chen, Hai Li, John L. Spudich, David S. Kliger

Biophys J. 2023 Oct 17; 122(20): 4091–4103. Published online 2023 Sep 25. doi: 10.1016/j.bpj.2023.09.009

PMCID:: PMC10598346

Abstract Article PDF–2.9M

Select item 1073068913.

Combining different ion-selective channelrhodopsins to control water flux by light

Fei Lin, Ruijing Tang, Chong Zhang, Nicole Scholz, Georg Nagel, Shiqiang Gao

Pflugers Arch. 2023; 475(12): 1375–1385. Published online 2023 Sep 5. doi: 10.1007/s00424-023-02853-5

PMCID:: PMC10730689

Abstract Article PDF–4.7M

Select item 1048797914.

Bioinformatics Analysis of MSH1 Genes of Green Plants: Multiple Parallel Length Expansions, Intron Gains and Losses, Partial Gene Duplications, and Alternative Splicing

Ming-Zhu Bai, Yan-Yan Guo

Int J Mol Sci. 2023 Sep; 24(17): 13620. Published online 2023 Sep 3. doi: 10.3390/ijms241713620

PMCID:: PMC10487979

Abstract Article PDF–4.6M

Select item 1046813615.

Origin and functional diversification of PAS domain, a ubiquitous intracellular sensor

Jiawei Xing, Vadim M. Gumerov, Igor B. Zhulin

Sci Adv. 2023 Sep; 9(35): eadi4517. Published online 2023 Aug 30. doi: 10.1126/sciadv.adi4517

PMCID:: PMC10468136

Abstract Article PDF–1.3M

Select item 1043523216.

Optogenetic manipulation of neuronal and cardiomyocyte functions in zebrafish using microbial rhodopsins and adenylyl cyclases

Hanako Hagio, Wataru Koyama, Shiori Hosaka, Aysenur Deniz Song, Janchiv Narantsatsral, Koji Matsuda, Takashi Shimizu, Shoko Hososhima, Satoshi P Tsunoda, Hideki Kandori, Masahiko Hibi

eLife. 2023; 12: e83975. Published online 2023 Aug 17. doi: 10.7554/eLife.83975