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Select item 110895041.

Identification of Potent and Selective Inhibitors of Acanthamoeba: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target

Tatiana Y. Hargrove, David C. Lamb, Zdzislaw Wawrzak, Marcus Hull, Steven L. Kelly, F. Peter Guengerich, Galina I. Lepesheva

J Med Chem. 2024 May 9; 67(9): 7443–7457. Published online 2024 Apr 29. doi: 10.1021/acs.jmedchem.4c00303

PMCID:: PMC11089504

Abstract Article PDF–11M

Select item 107628962.

Membrane-anchored calpains – hidden regulators of growth and development beyond plants?

Martin Šafranek, Alain Shumbusho, Wenche Johansen, Júlia Šarkanová, Stanislav Voško, Boris Bokor, Ján Jásik, Viktor Demko

Front Plant Sci. 2023; 14: 1289785. Published online 2023 Dec 19. doi: 10.3389/fpls.2023.1289785

PMCID:: PMC10762896

Abstract Article PDF–9.5M

Select item 104928463.

One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade

Jazmin Blaz, Luis Javier Galindo, Aaron A. Heiss, Harpreet Kaur, Guifré Torruella, Ashley Yang, L. Alexa Thompson, Alexander Filbert, Sally Warring, Apurva Narechania, Takashi Shiratori, Ken-ichiro Ishida, Joel B. Dacks, Purificación López-García, David Moreira, Eunsoo Kim, Laura Eme

Sci Data. 2023; 10: 603. Published online 2023 Sep 9. doi: 10.1038/s41597-023-02488-2

PMCID:: PMC10492846

Abstract Article PDF–3.1M

Select item 104681364.

Origin and functional diversification of PAS domain, a ubiquitous intracellular sensor

Jiawei Xing, Vadim M. Gumerov, Igor B. Zhulin

Sci Adv. 2023 Sep; 9(35): eadi4517. Published online 2023 Aug 30. doi: 10.1126/sciadv.adi4517

PMCID:: PMC10468136

Abstract Article PDF–1.3M

Select item 104133285.

Origin and Evolution of RAS Membrane Targeting

Antonio García-España, Mark R. Philips

Oncogene. Author manuscript; available in PMC 2023 Aug 10.

Published in final edited form as: Oncogene. 2023 May; 42(21): 1741–1750. Published online 2023 Apr 8. doi: 10.1038/s41388-023-02672-z

PMCID:: PMC10413328

Abstract Article PDF–2.8M

Select item 100149576.

Community dynamics of microbial eukaryotes in intertidal mudflats in the hypertidal Bay of Fundy

Eke I. Kalu, Adrian Reyes-Prieto, Myriam A. Barbeau

ISME Commun. 2023; 3: 21. Published online 2023 Mar 14. doi: 10.1038/s43705-023-00226-8

PMCID:: PMC10014957

Abstract Article PDF–2.2M

Select item 100160637.

Horizontal Gene Transfer and Fusion Spread Carotenogenesis Among Diverse Heterotrophic Protists

Mariana Rius, Joshua S Rest, Gina V Filloramo, Anna M G Novák Vanclová, John M Archibald, Jackie L Collier

Genome Biol Evol. 2023 Mar; 15(3): evad029. Published online 2023 Feb 20. doi: 10.1093/gbe/evad029

PMCID:: PMC10016063

Abstract Article PDF–5.0M

Select item 99980908.

Structural screens identify candidate human homologs of insect chemoreceptors and cryptic Drosophila gustatory receptor-like proteins

Richard Benton, Nathaniel J Himmel

eLife. 2023; 12: e85537. Published online 2023 Feb 20. doi: 10.7554/eLife.85537

PMCID:: PMC9998090

Abstract Article PDF–4.2M

Select item 100699079.

Mitochondrial ferredoxin-like is essential for forming complex I-containing supercomplexes in Arabidopsis

Helene Röhricht, Jonathan Przybyla-Toscano, Joachim Forner, Clément Boussardon, Olivier Keech, Nicolas Rouhier, Etienne H Meyer

Plant Physiol. 2023 Apr; 191(4): 2170–2184. Published online 2023 Jan 25. doi: 10.1093/plphys/kiad040

PMCID:: PMC10069907

Abstract Article PDF–860K

Select item 988762210.

Integrating Phylogenetics With Intron Positions Illuminates the Origin of the Complex Spliceosome

Julian Vosseberg, Daan Stolker, Samuel H A von der Dunk, Berend Snel

Mol Biol Evol. 2023 Jan; 40(1): msad011. Published online 2023 Jan 12. doi: 10.1093/molbev/msad011

PMCID:: PMC9887622

Abstract Article PDF–2.3M

Select item 980466511.

Evolution of factors shaping the endoplasmic reticulum

Aspasia Kontou, Emily K. Herman, Mark C. Field, Joel B. Dacks, V. Lila Koumandou

Traffic. 2022 Sep; 23(9): 462–473. Published online 2022 Aug 17. doi: 10.1111/tra.12863

Correction in:: Traffic. 2022 Oct; 23(10): 521.

PMCID:: PMC9804665

Abstract Article PDF–2.6M

Select item 936662912.

Phylogenomic Analyses of 2,786 Genes in 158 Lineages Support a Root of the Eukaryotic Tree of Life between Opisthokonts and All Other Lineages

Mario A Cerón-Romero, Miguel M Fonseca, Leonardo de Oliveira Martins, David Posada, Laura A Katz

Genome Biol Evol. 2022 Aug; 14(8): evac119. Published online 2022 Jul 26. doi: 10.1093/gbe/evac119

PMCID:: PMC9366629

Abstract Article PDF–322K

Select item 931150013.

Does the Actin Network Architecture Leverage Myosin-I Functions?

Julien Pernier, Kristine Schauer

Biology (Basel) 2022 Jul; 11(7): 989. Published online 2022 Jun 29. doi: 10.3390/biology11070989

PMCID:: PMC9311500

Abstract Article PDF–1.1M

Select item 761303414.

A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution

Xavier Grau-Bové, Cristina Navarrete, Cristina Chiva, Thomas Pribasnig, Meritxell Antó, Guifré Torruella, Luis Javier Galindo, Bernd Franz Lang, David Moreira, Purificación López-Garcia, Iñaki Ruiz-Trillo, Christa Schleper, Eduard Sabidó, Arnau Sebé-Pedrós

Nat Ecol Evol. Author manuscript; available in PMC 2022 Oct 9.

Published in final edited form as: Nat Ecol Evol. 2022 Jul; 6(7): 1007–1023. Published online 2022 Jun 9. doi: 10.1038/s41559-022-01771-6

PMCID:: PMC7613034

Abstract Article PDF–8.2M

Select item 901487315.

The Pet127 protein is a mitochondrial 5′-to-3′ exoribonuclease from the PD-(D/E)XK superfamily involved in RNA maturation and intron degradation in yeasts

Karolina Łabędzka-Dmoch, Michal Rażew, Marta Gapińska, Jakub Piątkowski, Adam Kolondra, Hanna Salmonowicz, Joanna M. Wenda, Marcin Nowotny, Paweł Golik

RNA. 2022 May; 28(5): 711–728. doi: 10.1261/rna.079083.121

PMCID:: PMC9014873

Abstract Article PDF–3.3M

Select item 972377816.

Metabarcoding the Antarctic Peninsula biodiversity using a multi-gene approach

V. G. Fonseca, A. Kirse, H. Giebner, B. J. Vause, T. Drago, D. M. Power, L. S. Peck, M. S. Clark

ISME Commun. 2022; 2: 37. Published online 2022 Apr 13. doi: 10.1038/s43705-022-00118-3

PMCID:: PMC9723778

Abstract Article PDF–2.3M

Select item 874030117.

Microbial Eukaryotes Associated With Sediments in Deep-Sea Cold Seeps

Yue Zhang, Ning Huang, Minxiao Wang, Hongbin Liu, Hongmei Jing

Front Microbiol. 2021; 12: 782004. Published online 2021 Dec 22. doi: 10.3389/fmicb.2021.782004

PMCID:: PMC8740301

Abstract Article PDF–4.9M

Select item 929294418.

Improved high throughput protocol for targeting eukaryotic symbionts in metazoan and eDNA samples

Diana Minardi, David Ryder, Javier del Campo, Vera Garcia Fonseca, Rose Kerr, Stein Mortensen, Alberto Pallavicini, David Bass

Mol Ecol Resour. 2022 Feb; 22(2): 664–678. Published online 2021 Oct 1. doi: 10.1111/1755-0998.13509

PMCID:: PMC9292944

Abstract Article PDF–1.3M

Select item 841631419.

Glutamate 73 Promotes Anti-arrhythmic Effects of Voltage-Dependent Anion Channel Through Regulation of Mitochondrial Ca²⁺ Uptake

Hirohito Shimizu, Simon Huber, Adam D. Langenbacher, Lauren Crisman, Jie Huang, Kevin Wang, Fabiola Wilting, Thomas Gudermann, Johann Schredelseker, Jau-Nian Chen

Front Physiol. 2021; 12: 724828. Published online 2021 Aug 18. doi: 10.3389/fphys.2021.724828