Volume 15(3); 2024 Mar 14
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Editorials
Forging a Future Free from Neglected Tropical Diseases
Flavio da Silva
Emery, Kelly Chibale
ACS Med Chem Lett. 2024 Mar 14; 15(3): 314–315. Published online 2024 Feb 26. doi: 10.1021/acsmedchemlett.4c00060
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PubMedTips for
Getting Your Manuscript Accepted into ACS Medicinal Chemistry
Letters
John G. Woodland, Kelly Chibale
ACS Med Chem Lett. 2024 Mar 14; 15(3): 316–317. Published online 2024 Feb 27. doi: 10.1021/acsmedchemlett.4c00059
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PubMedExpression of Concern
Expression of Concern for “Molecular Biology
Clues Portray SARS-CoV-2 as a Gain-of-Function Laboratory Manipulation
of Bat CoV RaTG13”
Dennis Liotta
ACS Med Chem Lett. 2024 Mar 14; 15(3): 423. Published online 2021 Oct 12. doi: 10.1021/acsmedchemlett.1c00525
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PubMedFeatured Letter
64Cu-Labeled Boron-Containing Cyclic RGD
Peptides for BNCT and PET Imaging
Soyeon Kim, Sajid Mushtaq, Kyo Chul Lee, Ji Ae Park, Jung Young Kim
ACS Med Chem Lett. 2024 Mar 14; 15(3): 344–348. Published online 2024 Feb 21. doi: 10.1021/acsmedchemlett.4c00007
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PubMedLetters
Rose Campbell, Nicklas W. Buchbinder, Connor Szwetkowski, Yumeng Zhu, Karla Piedl, Mindy Truong, John B. Matson, Webster L. Santos, Emily Mevers
ACS Med Chem Lett. 2024 Mar 14; 15(3): 349–354. Published online 2024 Feb 22. doi: 10.1021/acsmedchemlett.3c00463
Discovery
and Characterization of Active CBP/EP300
Degraders Targeting the HAT Domain
Iván Cheng-Sánchez, Katherine A. Gosselé, Leonardo Palaferri, Mariia S. Kirillova, Cristina Nevado
ACS Med Chem Lett. 2024 Mar 14; 15(3): 355–361. Published online 2024 Jan 26. doi: 10.1021/acsmedchemlett.3c00490
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PubMedCole Gannett, Kateland Tiller, Anthony J. Briganti, Anne M. Brown, James Weger-Lucarelli, Andrew N. Lowell
ACS Med Chem Lett. 2024 Mar 14; 15(3): 362–368. Published online 2024 Feb 23. doi: 10.1021/acsmedchemlett.3c00527
Vittorio Canale, Iwona Skiba-Kurek, Karolina Klesiewicz, Monika Papież, Marlena Ropek, Bartosz Pomierny, Kamil Piska, Paulina Koczurkiewicz-Adamczyk, Joanna Empel, Elżbieta Karczewska, Paweł Zajdel
ACS Med Chem Lett. 2024 Mar 14; 15(3): 369–375. Published online 2024 Feb 5. doi: 10.1021/acsmedchemlett.3c00536
Suppressive
Effects of Neuromedin U Receptor 2-Selective
Peptide Agonists on Appetite and Prolactin Secretion in Mice
Asuka Nomoto, Yui Suzuki, Katsuya Morito, Kazuki Nagasawa, Kentaro Takayama
ACS Med Chem Lett. 2024 Mar 14; 15(3): 376–380. Published online 2024 Feb 14. doi: 10.1021/acsmedchemlett.3c00541
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PubMedDiscovery
of Alternative Binding Poses through Fragment-Based
Identification of DHODH Inhibitors
Lindsey G. DeRatt, E. Christine Pietsch, Justin S. Cisar, Edgar Jacoby, Faraz Kazmi, Rosalie Matico, Paul Shaffer, Alexandra Tanner, Weixue Wang, Ricardo Attar, James P. Edwards, Scott D. Kuduk
ACS Med Chem Lett. 2024 Mar 14; 15(3): 381–387. Published online 2024 Feb 7. doi: 10.1021/acsmedchemlett.3c00543
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PubMedSelective
Recognition of c-KIT 1 G-Quadruplex
by Structural Tuning of Heteroaromatic Scaffolds
and Side Chains
Khushnood Fatma, Prasanth Thumpati, Deepanjan Panda, Ravichandiran Velayutham, Jyotirmayee Dash
ACS Med Chem Lett. 2024 Mar 14; 15(3): 388–395. Published online 2024 Feb 12. doi: 10.1021/acsmedchemlett.3c00537
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PubMedNovel-Type GABAB PAMs: Structure–Activity
Relationship in Light of the Protein Structure
Balázs Krámos, Zsuzsa Hadady, Attila Makó, Gábor Szántó, Nóra Felföldi, Ildikó Magdó, Amrita Ágnes Bobok, Imre Bata, Viktor Román, András Visegrády, György
M. Keserű, István Greiner, János Éles
ACS Med Chem Lett. 2024 Mar 14; 15(3): 396–405. Published online 2024 Mar 1. doi: 10.1021/acsmedchemlett.3c00560
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PubMedZX703: A Small-Molecule Degrader of GPX4 Inducing
Ferroptosis in Human Cancer Cells
Mengdie Hu, Xiaomei Li, Lin Wang, Yanping Zhang, Yujie Sun, Hui Hua, Huina Liu, Ting Cai, Dongsheng Zhu, Qiuping Xiang
ACS Med Chem Lett. 2024 Mar 14; 15(3): 406–412. Published online 2024 Feb 15. doi: 10.1021/acsmedchemlett.3c00571
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PubMedNotes
Laszlo Kondacs, Priyanka Parijat, Alexander J. A. Cobb, Thomas Kampourakis
ACS Med Chem Lett. 2024 Mar 14; 15(3): 413–417. Published online 2024 Feb 7. doi: 10.1021/acsmedchemlett.3c00511
Probing the Use of Triphenyl Phosphonium Cation for
Mitochondrial Nucleoside Delivery
Mathis Guiraud, Lamiaa M. A. Ali, Emma Gabrieli-Magot, Laure Lichon, Morgane Daurat, David Egron, Magali Gary-Bobo, Suzanne Peyrottes
ACS Med Chem Lett. 2024 Mar 14; 15(3): 418–422. Published online 2024 Feb 15. doi: 10.1021/acsmedchemlett.3c00568
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PubMedPatent Highlight
Novel Tetrahydropyrido[3,4-d]pyrimidines as HPK1 Inhibitors for Treating Cancer, Inflammatory,
and Autoimmune Diseases
Ram W. Sabnis
ACS Med Chem Lett. 2024 Mar 14; 15(3): 318–319. Published online 2024 Jan 31. doi: 10.1021/acsmedchemlett.4c00023
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PubMedTYK2 Inhibitors
for Treating Autoimmune and Inflammatory
Diseases
Ram W. Sabnis
ACS Med Chem Lett. 2024 Mar 14; 15(3): 320–321. Published online 2024 Feb 6. doi: 10.1021/acsmedchemlett.4c00024
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PubMedPyrrolidinone
Derivatives as NIK Inhibitors for Treating
Inflammatory and Autoimmune Diseases
Ram W. Sabnis
ACS Med Chem Lett. 2024 Mar 14; 15(3): 322–323. Published online 2024 Feb 14. doi: 10.1021/acsmedchemlett.4c00044
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PubMedNovel Heterocyclic
Compounds for Treating Huntington’s
Disease
Ram W. Sabnis, Anika R. Sabnis
ACS Med Chem Lett. 2024 Mar 14; 15(3): 324–325. Published online 2024 Feb 13. doi: 10.1021/acsmedchemlett.4c00045
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PubMedNovel AT2R
Antagonists for Treating Chronic Pain
Ram W. Sabnis
ACS Med Chem Lett. 2024 Mar 14; 15(3): 326–327. Published online 2024 Feb 13. doi: 10.1021/acsmedchemlett.4c00046
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PubMedInnovations
in Pharmacology: Enhancing Bioavailability
and Efficacy through Novel Compositions
Robert B. Kargbo
ACS Med Chem Lett. 2024 Mar 14; 15(3): 328–330. Published online 2024 Feb 13. doi: 10.1021/acsmedchemlett.4c00055
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PubMedAdvancements in Predictive Medicine: NLRP3 Inflammasome
Inhibitors and AI-Driven Predictive Health Analytics
Robert B. Kargbo
ACS Med Chem Lett. 2024 Mar 14; 15(3): 331–333. Published online 2024 Feb 13. doi: 10.1021/acsmedchemlett.4c00056
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PubMedAI in Pharma:
Transforming Drug Discovery and Strategic
Management with MYC-Modulating Compounds and BET Protein Inhibitors
Robert B. Kargbo
ACS Med Chem Lett. 2024 Mar 14; 15(3): 334–336. Published online 2024 Feb 13. doi: 10.1021/acsmedchemlett.4c00057
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PubMedPioneering Methods in Brain Optimization and Mental
Health Treatment
Robert B. Kargbo
ACS Med Chem Lett. 2024 Mar 14; 15(3): 337–339. Published online 2024 Feb 13. doi: 10.1021/acsmedchemlett.4c00058
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PubMedNovel Heterocyclic PAD4 Inhibitors for Treating Diseases
Ram W. Sabnis
ACS Med Chem Lett. 2024 Mar 14; 15(3): 340–341. Published online 2024 Feb 27. doi: 10.1021/acsmedchemlett.4c00075
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PubMedCombination
of Allosteric and Orthosteric EGFR Inhibitors
for Treating Non-Small-Cell Lung Cancer
Ram W. Sabnis
ACS Med Chem Lett. 2024 Mar 14; 15(3): 342–343. Published online 2024 Feb 27. doi: 10.1021/acsmedchemlett.4c00076
Currently embargoed: Free in PMC on Mar 14, 2025;
PubMed
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