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Items: 1 to 20 of 310

1.
Histone deacetylase 6’s function in viral infection, innate immunity, and disease: latest advances
Min Qu, Huijun Zhang, Pengyuan Cheng, Ashenafi Kiros Wubshet, Xiangping Yin, Xiangwei Wang, Yuefeng Sun
Front Immunol. 2023; 14: 1216548. Published online 2023 Aug 11. doi: 10.3389/fimmu.2023.1216548
PMCID:
PMC10450946
AbstractArticlePDF–1.4M
2.
Inhibition of histone deacetylase 6 destabilizes ERK phosphorylation and suppresses cancer proliferation via modulation of the tubulin acetylation-GRP78 interaction
Onsurang Wattanathamsan, Naphat Chantaravisoot, Piriya Wongkongkathep, Sakkarin Kungsukool, Paninee Chetprayoon, Pithi Chanvorachote, Chanida Vinayanuwattikun, Varisa Pongrakhananon
J Biomed Sci. 2023; 30: 4. Published online 2023 Jan 13. doi: 10.1186/s12929-023-00898-3
PMCID:
PMC9838051
AbstractArticlePDF–2.6M
3.
HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy
Lang Shi, Zhixia Song, Chenglong Li, Fangjing Deng, Yao Xia, Jing Huang, Xiongfei Wu, Jiefu Zhu
Cells. 2022 Dec; 11(24): 3951. Published online 2022 Dec 7. doi: 10.3390/cells11243951
PMCID:
PMC9776591
AbstractArticlePDF–13M
4.
HDAC6 Substrate Discovery Using Proteomics-Based Substrate Trapping: HDAC6 Deacetylates PRMT5 to Influence Methyltransferase Activity
Inosha D. Gomes, Udana V. Ariyaratne, Mary Kay H. Pflum
ACS Chem Biol. Author manuscript; available in PMC 2022 Aug 20.
Published in final edited form as: ACS Chem Biol. 2021 Aug 20; 16(8): 1435–1444. Published online 2021 Jul 27. doi: 10.1021/acschembio.1c00303
PMCID:
PMC8939004
AbstractArticlePDF–1.1M
5.
HDAC6 is critical for ketamine-induced impairment of dendritic and spine growth in GABAergic projection neurons
Xuan Li, Hexige Saiyin, Jian-hua Zhou, Qiong Yu, Wei-min Liang
Acta Pharmacol Sin. 2021 Jun; 42(6): 861–870. Published online 2020 Sep 16. doi: 10.1038/s41401-020-00521-3
PMCID:
PMC8149677
AbstractArticlePDF–6.2M
6.
Correlation analysis between expression of histone deacetylase 6 and clinical parameters in IgA nephropathy patients
Yan Hu, Minghua Shang, Yingfeng Shi, Min Tao, Weijie Yuan, Lunxian Tang, Xiaoyan Ma, Binbin Cui, Hui Chen, Xun Zhou, Shougang Zhuang, Na Liu
Ren Fail. 2021; 43(1): 684–697. Published online 2021 Apr 26. doi: 10.1080/0886022X.2021.1914657
PMCID:
PMC8079031
AbstractArticlePDF–2.9M
7.
HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations
Raheem Fazal, Steven Boeynaems, Ann Swijsen, Mathias De Decker, Laura Fumagalli, Matthieu Moisse, Joni Vanneste, Wenting Guo, Ruben Boon, Thomas Vercruysse, Kristel Eggermont, Bart Swinnen, Jimmy Beckers, Donya Pakravan, Tijs Vandoorne, Pieter Vanden Berghe, Catherine Verfaillie, Ludo Van Den Bosch, Philip Van Damme
EMBO J. 2021 Apr 1; 40(7): e106177. Published online 2021 Mar 10. doi: 10.15252/embj.2020106177
PMCID:
PMC8013789
AbstractArticlePDF–3.9M
8.
Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer
Catríona M. Dowling, Kate E. R. Hollinshead, Alessandra Di Grande, Justin Pritchard, Hua Zhang, Eugene T. Dillon, Kathryn Haley, Eleni Papadopoulos, Anita K. Mehta, Rachel Bleach, Andreas U. Lindner, Brian Mooney, Heiko Düssmann, Darran O’Connor, Jochen H. M. Prehn, Kieran Wynne, Michael Hemann, James E. Bradner, Alec C. Kimmelman, Jennifer L. Guerriero, Gerard Cagney, Kwok-Kin Wong, Anthony G. Letai, Tríona Ní Chonghaile
Sci Adv. 2021 Jan; 7(3): eabc4897. Published online 2021 Jan 15. doi: 10.1126/sciadv.abc4897
PMCID:
PMC7810372
AbstractArticlePDF–1.3M
9.
Membrane-Associated α-Tubulin Is Less Acetylated in Postmortem Prefrontal Cortex from Depressed Subjects Relative to Controls: Cytoskeletal Dynamics, HDAC6, and Depression
Harinder Singh, Justyna Chmura, Runa Bhaumik, Ghanshyam N. Pandey, Mark M. Rasenick
J Neurosci. 2020 May 13; 40(20): 4033–4041. doi: 10.1523/JNEUROSCI.3033-19.2020
Correction in:
J Neurosci. 2024 May 15; 44(20): e0720242024.
PMCID:
PMC7219287
AbstractArticlePDF–1.3M
10.
HDAC6 promotes sepsis development by impairing PHB1-mediated mitochondrial respiratory chain function
Shi-dong Guo, Sheng-tao Yan, Wen Li, Hong Zhou, Jian-ping Yang, Yao Yao, Mei-jia Shen, Liu-wei Zhang, Hong-Bo Zhang, Li-Chao Sun
Aging (Albany NY) 2020 Mar 31; 12(6): 5411–5422. Published online 2020 Mar 28. doi: 10.18632/aging.102964
PMCID:
PMC7138540
AbstractArticlePDF–1.2M
11.
2-Methylquinazoline derivative 23BB as a highly selective histone deacetylase 6 inhibitor alleviated cisplatin-induced acute kidney injury
Yan Hao, Fan Guo, Zhuo Huang, Yuying Feng, Zijing Xia, Jing Liu, Lingzhi Li, Rongshuang Huang, Lin Lin, Liang Ma, Ping Fu
Biosci Rep. 2020 Jan 31; 40(1): BSR20191538. Published online 2020 Jan 17. doi: 10.1042/BSR20191538
PMCID:
PMC6970081
AbstractArticlePDF–5.0M
12.
Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6
Jeremy D. Osko, David W. Christianson
Biochemistry. Author manuscript; available in PMC 2020 Dec 10.
Published in final edited form as: Biochemistry. 2019 Dec 10; 58(49): 4912–4924. Published online 2019 Dec 2. doi: 10.1021/acs.biochem.9b00934
PMCID:
PMC6904440
AbstractArticlePDF–2.7M
13.
HDAC6 differentially regulates autophagy in stem-like versus differentiated cancer cells
Tanveer Sharif, Emma Martell, Cathleen Dai, Mohammad Saleh Ghassemi-Rad, Mark Robert Hanes, Patrick J. Murphy, Nandini N. Margam, Hirendrasinh B. Parmar, Carman A. Giacomantonio, Roy Duncan, Patrick W.K. Lee, Shashi Gujar
Autophagy. 2019; 15(4): 686–706. Published online 2018 Dec 4. doi: 10.1080/15548627.2018.1548547
PMCID:
PMC6526821
AbstractArticlePDF–4.8M
14.
HDAC6 is associated with the formation of aortic dissection in human
Xian Guo, Ze-Min Fang, Xiang Wei, Bo Huo, Xin Yi, Cai Cheng, Jun Chen, Xue-Hai Zhu, Anas Omar Khalil Abu Bokha, Ding-Sheng Jiang
Mol Med. 2019; 25: 10. Published online 2019 Mar 29. doi: 10.1186/s10020-019-0080-7
PMCID:
PMC6441237
AbstractArticlePDF–4.3M
15.
Targeted inhibition of histone deacetylase 6 in inflammatory diseases
Jie Ran, Jun Zhou
Thorac Cancer. 2019 Mar; 10(3): 405–412. Published online 2019 Jan 21. doi: 10.1111/1759-7714.12974
PMCID:
PMC6397899
AbstractArticlePDF–642K
16.
NBM-T-BBX-OS01, Semisynthesized from Osthole, Induced G1 Growth Arrest through HDAC6 Inhibition in Lung Cancer Cells
Jih-Tung Pai, Chia-Yun Hsu, Kuo-Tai Hua, Sheng-Yung Yu, Chung-Yang Huang, Chia-Nan Chen, Chiung-Ho Liao, Meng-Shih Weng
Molecules. 2015 May; 20(5): 8000–8019. Published online 2015 May 4. doi: 10.3390/molecules20058000
PMCID:
PMC6272357
AbstractArticlePDF–1.0M
17.
The Therapeutic Strategy of HDAC6 Inhibitors in Lymphoproliferative Disease
Maria Cosenza, Samantha Pozzi
Int J Mol Sci. 2018 Aug; 19(8): 2337. Published online 2018 Aug 9. doi: 10.3390/ijms19082337
PMCID:
PMC6121661
AbstractArticlePDF–1.1M
18.
Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6
Nicholas J. Porter, Florence F. Wagner, David W. Christianson
Biochemistry. Author manuscript; available in PMC 2019 Jul 3.
Published in final edited form as: Biochemistry. 2018 Jul 3; 57(26): 3916–3924. Published online 2018 May 18. doi: 10.1021/acs.biochem.8b00367
PMCID:
PMC6030506
AbstractArticlePDF–1.1M
19.
Targeted Proteomic Analyses of Histone H4 Acetylation Changes Associated with Homologous-Recombination-Deficient High-Grade Serous Ovarian Carcinomas
Stefani N. Thomas, Lijun Chen, Yang Liu, Naseruddin Höti, Hui Zhang
J Proteome Res. Author manuscript; available in PMC 2017 Oct 7.
Published in final edited form as: J Proteome Res. 2017 Oct 6; 16(10): 3704–3710. Published online 2017 Sep 14. doi: 10.1021/acs.jproteome.7b00405
PMCID:
PMC5630524
AbstractArticlePDF–455K
20.
Ricolinostat, the first selective histone deacetylase 6 inhibitor, in combination with bortezomib and dexamethasone for relapsed or refractory multiple myeloma
Dan T. Vogl, Noopur Raje, Sundar Jagannath, Paul Richardson, Parameswaran Hari, Robert Orlowski, Jeffrey G. Supko, David Tamang, Min Yang, Simon S. Jones, Catherine Wheeler, Robert J. Markelewicz, Sagar Lonial
Clin Cancer Res. Author manuscript; available in PMC 2018 Jan 1.
Published in final edited form as: Clin Cancer Res. 2017 Jul 1; 23(13): 3307–3315. Published online 2017 Jan 4. doi: 10.1158/1078-0432.CCR-16-2526
PMCID:
PMC5496796
AbstractArticlePDF–763K

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