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Select item 67593891.

DCAF7 is required for maintaining the cellular levels of ERCC1-XPF and nucleotide excision repair

Hiroaki Kawara, Ryo Akahori, Mitsuo Wakasugi, Aziz Sancar, Tsukasa Matsunaga

Biochem Biophys Res Commun. Author manuscript; available in PMC 2020 Oct 29.

Published in final edited form as: Biochem Biophys Res Commun. 2019 Oct 29; 519(1): 204–210. Published online 2019 Sep 4. doi: 10.1016/j.bbrc.2019.08.147

PMCID:: PMC6759389

Abstract Article PDF–990K

Select item 62648482.

DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B

Mina Yousefelahiyeh, Jingyi Xu, Estibaliz Alvarado, Yang Yu, David Salven, Robert M. Nissen

PLoS One. 2018; 13(11): e0207779. Published online 2018 Nov 29. doi: 10.1371/journal.pone.0207779

PMCID:: PMC6264848

Abstract Article PDF–2.6M

Select item 50639743.

Human DNA Ligase I Interacts with and Is Targeted for Degradation by the DCAF7 Specificity Factor of the Cul4-DDB1 Ubiquitin Ligase Complex

Zhimin Peng, Zhongping Liao, Yoshihiro Matsumoto, Austin Yang, Alan E. Tomkinson

J Biol Chem. 2016 Oct 14; 291(42): 21893–21902. Published online 2016 Aug 29. doi: 10.1074/jbc.M116.746198

PMCID:: PMC5063974

Abstract Article PDF–1.1M

Select item 62654674.

DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers

Shanshan Li, Chu Xu, Yinkun Fu, Pin-Ji Lei, Yanhua Yao, Wanli Yang, Ying Zhang, Michael P Washburn, Laurence Florens, Manish Jaiswal, Min Wu, Man Mohan

Nucleic Acids Res. 2018 Nov 30; 46(21): 11202–11213. Published online 2018 Aug 22. doi: 10.1093/nar/gky754

PMCID:: PMC6265467

Abstract Article PDF–7.2M

Select item 45859765.

Selective autophagic receptor p62 regulates the abundance of transcriptional coregulator ARIP4 during nutrient starvation

Megumi Tsuchiya, Shin Isogai, Hiroaki Taniguchi, Hidehito Tochio, Masahiro Shirakawa, Ken-ichirou Morohashi, Yasushi Hiraoka, Tokuko Haraguchi, Hidesato Ogawa

Sci Rep. 2015; 5: 14498. Published online 2015 Sep 28. doi: 10.1038/srep14498

PMCID:: PMC4585976

Abstract Article PDF–1.8M

Select item 81960336.

K63-linked ubiquitination of DYRK1A by TRAF2 alleviates Sprouty 2-mediated degradation of EGFR

Pengshan Zhang, Zhe Zhang, Yinkun Fu, Ying Zhang, Michael P. Washburn, Laurence Florens, Min Wu, Chen Huang, Zhaoyuan Hou, Man Mohan

Cell Death Dis. 2021 Jun; 12(6): 608. Published online 2021 Jun 11. doi: 10.1038/s41419-021-03887-2

PMCID:: PMC8196033

Abstract Article PDF–4.2M

Select item 29891057.

The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions

Stefanie Ritterhoff, Carla M Farah, Julia Grabitzki, Günter Lochnit, Alexander V Skurat, Michael Lienhard Schmitz

EMBO J. 2010 Nov 17; 29(22): 3750–3761. Published online 2010 Oct 12. doi: 10.1038/emboj.2010.251

PMCID:: PMC2989105

Abstract Article PDF–1.0M

Select item 49101628.

The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2

Florian Glenewinkel, Michael J. Cohen, Cason R. King, Sophie Kaspar, Simone Bamberg-Lemper, Joe S. Mymryk, Walter Becker

Sci Rep. 2016; 6: 28241. Published online 2016 Jun 16. doi: 10.1038/srep28241

PMCID:: PMC4910162

Abstract Article PDF–2.1M

Select item 33951129.

ZNF703 gene amplification at 8p12 specifies luminal B breast cancer

Fabrice Sircoulomb, Nathalie Nicolas, Anthony Ferrari, Pascal Finetti, Ismahane Bekhouche, Estelle Rousselet, Aurélie Lonigro, José Adélaïde, Emilie Baudelet, Séverine Esteyriès, Julien Wicinski, Stéphane Audebert, Emmanuelle Charafe-Jauffret, Jocelyne Jacquemier, Marc Lopez, Jean-Paul Borg, Christos Sotiriou, Cornel Popovici, François Bertucci, Daniel Birnbaum, Max Chaffanet, Christophe Ginestier

EMBO Mol Med. 2011 Mar; 3(3): 153–166. Published online 2011 Feb 15. doi: 10.1002/emmm.201100121

Correction in:: EMBO Mol Med. 2011 Mar; 3(3): NA.

PMCID:: PMC3395112

Abstract Article PDF–821K

Select item 424608910.

The Molecular Chaperone TRiC/CCT Binds to the Trp-Asp 40 (WD40) Repeat Protein WDR68 and Promotes Its Folding, Protein Kinase DYRK1A Binding, and Nuclear Accumulation

Yoshihiko Miyata, Takeshi Shibata, Masato Aoshima, Takuichi Tsubata, Eisuke Nishida

J Biol Chem. 2014 Nov 28; 289(48): 33320–33332. Published online 2014 Oct 22. doi: 10.1074/jbc.M114.586115

PMCID:: PMC4246089

Abstract Article PDF–2.6M

Select item 538932311.

Dual-utility NLS drives RNF169-dependent DNA damage responses

Liwei An, Yiyang Jiang, Howin H. W. Ng, Ellen P. S. Man, Jie Chen, Ui-Soon Khoo, Qingguo Gong, Michael S. Y. Huen

Proc Natl Acad Sci U S A. 2017 Apr 4; 114(14): E2872–E2881. Published online 2017 Mar 21. doi: 10.1073/pnas.1616602114

PMCID:: PMC5389323

Abstract Article PDF–1.6M

Select item 152320112.

A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression

Robert M Nissen, Adam Amsterdam, Nancy Hopkins

BMC Dev Biol. 2006; 6: 28. Published online 2006 Jun 7. doi: 10.1186/1471-213X-6-28

PMCID:: PMC1523201

Abstract Article PDF–1.7M

Select item 662592113.

Nrf2 activation promotes lung cancer metastasis by inhibiting the degradation of Bach1

Luca Lignitto, Sarah E. LeBoeuf, Harrison Homer, Shaowen Jiang, Manor Askenazi, Triantafyllia R. Karakousi, Harvey I. Pass, Arjun J. Bhutkar, Aristotelis Tsirigos, Beatrix Ueberheide, Volkan I. Sayin, Thales Papagiannakopoulos, Michele Pagano

Cell. Author manuscript; available in PMC 2020 Jul 11.

Published in final edited form as: Cell. 2019 Jul 11; 178(2): 316–329.e18. Published online 2019 Jun 27. doi: 10.1016/j.cell.2019.06.003

PMCID:: PMC6625921

Abstract Article PDF–3.1M

Select item 658157414.

Cryptochromes-mediated Inhibition of the CRL4^Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism

Luca Rizzini, Daniel C. Levine, Mark Perelis, Joseph Bass, Clara B. Peek, Michele Pagano

Curr Biol. Author manuscript; available in PMC 2020 Jun 17.

Published in final edited form as: Curr Biol. 2019 Jun 17; 29(12): 1954–1962.e4. Published online 2019 May 30. doi: 10.1016/j.cub.2019.04.073

PMCID:: PMC6581574

Abstract Article PDF–1.1M

Select item 339041315.

Proteomic Profiling of the TRAF3 Interactome Network Reveals a New Role for the ER-to-Golgi Transport Compartments in Innate Immunity

Wendy J. van Zuylen, Priscilla Doyon, Jean-François Clément, Kashif Aziz Khan, Lisa M. D'Ambrosio, Florence Dô, Myriam St-Amant-Verret, Tasheen Wissanji, Gregory Emery, Anne-Claude Gingras, Sylvain Meloche, Marc J. Servant

PLoS Pathog. 2012 Jul; 8(7): e1002747. Published online 2012 Jul 5. doi: 10.1371/journal.ppat.1002747

PMCID:: PMC3390413

Abstract Article PDF–1.8M

Select item 363036016.

OTUB1 modulates c-IAP1 stability to regulate signalling pathways

Tatiana Goncharov, Kyle Niessen, Maria Cristina de Almagro, Anita Izrael-Tomasevic, Anna V Fedorova, Eugene Varfolomeev, David Arnott, Kurt Deshayes, Donald S Kirkpatrick, Domagoj Vucic

EMBO J. 2013 Apr 17; 32(8): 1103–1114. Published online 2013 Mar 22. doi: 10.1038/emboj.2013.62

PMCID:: PMC3630360

Abstract Article PDF–2.0M

Select item 417315217.

ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes

Lisa D. Boxer, Brook Barajas, Shiying Tao, Jiajing Zhang, Paul A. Khavari

Genes Dev. 2014 Sep 15; 28(18): 2013–2026. doi: 10.1101/gad.246579.114

PMCID:: PMC4173152

Abstract Article PDF–2.1M

Select item 887529718.

CRL4^AMBRA1 is a master regulator of D-type cyclins

Daniele Simoneschi, Gergely Rona, Nan Zhou, Yeon-Tae Jeong, Shaowen Jiang, Giacomo Milletti, Arnaldo A. Arbini, Alfie O’Sullivan, Andrew A. Wang, Sorasicha Nithikasem, Sarah Keegan, Yik Siu, Valentina Cianfanelli, Emiliano Maiani, Francesca Nazio, Francesco Cecconi, Francesco Boccalatte, David Fenyö, Drew R. Jones, Luca Busino, Michele Pagano

Nature. Author manuscript; available in PMC 2022 Apr 14.

Published in final edited form as: Nature. 2021 Apr; 592(7856): 789–793. Published online 2021 Apr 14. doi: 10.1038/s41586-021-03445-y

PMCID:: PMC8875297

Abstract Article PDF–6.0M

Select item 444076919.

TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation

Hannah Greenfeld, Kaoru Takasaki, Michael J. Walsh, Ina Ersing, Katharina Bernhardt, Yijie Ma, Bishi Fu, Camille W. Ashbaugh, Jackson Cabo, Sarah B. Mollo, Hufeng Zhou, Shitao Li, Benjamin E. Gewurz

PLoS Pathog. 2015 May; 11(5): e1004890. Published online 2015 May 21. doi: 10.1371/journal.ppat.1004890

PMCID:: PMC4440769

Abstract Article PDF–5.7M

Select item 432309720.

AUTS2 confers gene activation to Polycomb group proteins in the CNS

Zhonghua Gao, Pedro Lee, James M. Stafford, Melanie von Schimmelmann, Anne Schaefer, Danny Reinberg

Nature. Author manuscript; available in PMC 2015 Jun 18.

Published in final edited form as: Nature. 2014 Dec 18; 516(7531): 349–354. doi: 10.1038/nature13921

PMCID:: PMC4323097

Abstract Article PDF–4.2M

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PMC Links for Gene (Select 10238) (110)
PMC
transcription factor RFX3 isoform X10 [Homo sapiens]
transcription factor RFX3 isoform X10 [Homo sapiens]
gi|2462625778|ref|XP_054219460.1|

Protein
PREDICTED: Homo sapiens regulatory factor X3 (RFX3), transcript variant X50, mRN...
PREDICTED: Homo sapiens regulatory factor X3 (RFX3), transcript variant X50, mRNA
gi|2462625789|ref|XM_054363491.1|

Nucleotide

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