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Select item 85343221.

Epigenetic DNA Modifications Upregulate SPRY2 in Human Colorectal Cancers

Alexei J. Stuckel, Shuai Zeng, Zhen Lyu, Wei Zhang, Xu Zhang, Urszula Dougherty, Reba Mustafi, Qiong Zhang, Trupti Joshi, Marc Bissonnette, Samrat Roy Choudhury, Sharad Khare

Cells. 2021 Oct; 10(10): 2632. Published online 2021 Oct 2. doi: 10.3390/cells10102632

PMCID:: PMC8534322

Abstract Article PDF–2.9M

Select item 64284292.

Genome-wide association study links receptor tyrosine kinase inhibitor Sprouty2 to thrombocytopenia after coronary artery bypass surgery

Jörn A. Karhausen, Wenjing Qi, Alan M. Smeltz, Yi-Ju Li, Svati H. Shah, William E. Kraus, Joseph P. Mathew, Mihai V. Podgoreanu, Miklos D. Kertai, Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team

Thromb Haemost. Author manuscript; available in PMC 2019 Mar 21.

Published in final edited form as: Thromb Haemost. 2018 Sep; 118(9): 1572–1585. Published online 2018 Aug 13. doi: 10.1055/s-0038-1667199

PMCID:: PMC6428429

Abstract Article PDF–1.2M

Select item 64066893.

Haplotype and Haplotype-Environment Interaction Analysis Revealed Roles of SPRY2 for NSCL/P among Chinese Populations

Ren Zhou, Mengying Wang, Wenyong Li, Siyue Wang, Hongchen Zheng, Zhibo Zhou, Yonghua Hu, Jing Li, Tao Wu, Hongping Zhu, Terri H. Beaty

Int J Environ Res Public Health. 2019 Feb; 16(4): 557. Published online 2019 Feb 15. doi: 10.3390/ijerph16040557

PMCID:: PMC6406689

Abstract Article PDF–281K

Select item 62801494.

Sprouty2 enhances the tumorigenic potential of glioblastoma cells

Jong-Whi Park, Guido Wollmann, Carles Urbiola, Barbara Fogli, Tullio Florio, Stephan Geley, Lars Klimaschewski

Neuro Oncol. 2018 Jul; 20(8): 1044–1054. Published online 2018 Feb 23. doi: 10.1093/neuonc/noy028

Correction in:: Neuro Oncol. 2018 Jul; 20(8): 1146–1147.

PMCID:: PMC6280149

Abstract Article PDF–20M

Select item 49449645.

Sprouty2 Suppresses Epithelial-Mesenchymal Transition of Human Lens Epithelial Cells through Blockade of Smad2 and ERK1/2 Pathways

Xuhua Tan, Yi Zhu, Chuan Chen, Xiaoyun Chen, Yingyan Qin, Bo Qu, Lixia Luo, Haotian Lin, Mingxing Wu, Weirong Chen, Yizhi Liu

PLoS One. 2016; 11(7): e0159275. Published online 2016 Jul 14. doi: 10.1371/journal.pone.0159275

PMCID:: PMC4944964

Abstract Article PDF–9.4M

Select item 47951966.

A SPRY2 mutation leading to MAPK/ERK pathway inhibition is associated with an autosomal dominant form of IgA nephropathy

Annamaria Milillo, Francesca La Carpia, Stefano Costanzi, Vanessa D'Urbano, Maurizio Martini, Paola Lanuti, Gisella Vischini, Luigi M Larocca, Marco Marchisio, Sebastiano Miscia, Antonio Amoroso, Fiorella Gurrieri, Eugenio Sangiorgi

Eur J Hum Genet. 2015 Dec; 23(12): 1673–1678. Published online 2015 Mar 18. doi: 10.1038/ejhg.2015.52

PMCID:: PMC4795196

Abstract Article PDF–1.2M

Select item 46791837.

SPROUTY2 DRIVES DRUG RESISTANCE AND PROLIFERATION IN GLIOBLASTOMA

Alice M. Walsh, Gurpreet S. Kapoor, Janine M. Buonato, Lijoy K. Mathew, Yingtao Bi, Ramana V. Davuluri, Maria Martinez-Lage, M. Celeste Simon, Donald M. O’Rourke, Matthew J. Lazzara

Mol Cancer Res. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: Mol Cancer Res. 2015 Aug; 13(8): 1227–1237. Published online 2015 May 1. doi: 10.1158/1541-7786.MCR-14-0183-T

PMCID:: PMC4679183

Abstract Article PDF–2.2M

Select item 36160128.

Expression and Functional Role of Sprouty-2 in Breast Morphogenesis

Valgardur Sigurdsson, Saevar Ingthorsson, Bylgja Hilmarsdottir, Sigrun M. Gustafsdottir, Sigridur Rut Franzdottir, Ari Jon Arason, Eirikur Steingrimsson, Magnus K. Magnusson, Thorarinn Gudjonsson

PLoS One. 2013; 8(4): e60798. Published online 2013 Apr 3. doi: 10.1371/journal.pone.0060798

PMCID:: PMC3616012

Abstract Article PDF–2.8M

Select item 31661199.

Sprouty 2 Is an Independent Prognostic Factor in Breast Cancer and May Be Useful in Stratifying Patients for Trastuzumab Therapy

Dana Faratian, Andrew H. Sims, Peter Mullen, Charlene Kay, InHwa Um, Simon P. Langdon, David J. Harrison

PLoS One. 2011; 6(8): e23772. Published online 2011 Aug 31. doi: 10.1371/journal.pone.0023772

PMCID:: PMC3166119

Abstract Article PDF–833K

Select item 261361310.

Sprouty 2 Regulates DNA Damage-induced Apoptosis in Ras-transformed Human Fibroblasts

Piro Lito, Bryan D. Mets, Daniel M. Appledorn, Veronica M. Maher, J. Justin McCormick

J Biol Chem. 2009 Jan 9; 284(2): 848–854. doi: 10.1074/jbc.M808045200

PMCID:: PMC2613613

Abstract Article PDF–441K

Select item 119635111.

Sprouty-2 Overexpression in C2C12 Cells Confers Myogenic Differentiation Properties in the Presence of FGF2

Cristina de Alvaro, Natalia Martinez, Jose M. Rojas, Margarita Lorenzo

Mol Biol Cell. 2005 Sep; 16(9): 4454–4461. doi: 10.1091/mbc.E05-05-0419

PMCID:: PMC1196351

Abstract Article PDF–509K

Select item 1115951312.

Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells

Yin‐Hsun Feng, Chao‐Jung Tsao, Chao‐Liang Wu, Jan‐Gowth Chang, Pei‐Jung Lu, Kun‐Tu Yeh, Gia‐Shing Shieh, Ai‐Li Shiau, Jeng‐Chang Lee

Cancer Sci. 2010 Sep; 101(9): 2033–2038. Published online 2010 Jun 7. doi: 10.1111/j.1349-7006.2010.01637.x

PMCID:: PMC11159513

Abstract Article PDF–521K

Select item 1115897513.

Sprouty2 regulates growth and differentiation of human neuroblastoma cells through RET tyrosine kinase

Maki Ishida, Masatoshi Ichihara, Shinji Mii, Mayumi Jijiwa, Naoya Asai, Atsushi Enomoto, Takuya Kato, Ai Majima, Jiang Ping, Yoshiki Murakumo, Masahide Takahashi

Cancer Sci. 2007 Jun; 98(6): 815–821. Published online 2007 Mar 27. doi: 10.1111/j.1349-7006.2007.00457.x

PMCID:: PMC11158975

Abstract Article PDF–275K

Select item 1111554914.

Bimodal expression of Sprouty2 during the cell cycle is mediated by phase-specific Ras/MAPK and c-Cbl activities

Christoph-Erik Mayer, Barbara Haigl, Florian Jantscher, Gerald Siegwart, Michael Grusch, Walter Berger, Hedwig Sutterlüty

Cell Mol Life Sci. 2010 Oct; 67(19): 3299–3311. Published online 2010 May 12. doi: 10.1007/s00018-010-0379-6

PMCID:: PMC11115549

Abstract Article PDF–796K

Select item 1037567715.

Loss of SPRY2 contributes to cancer-associated fibroblasts activation and promotes breast cancer development

Huijuan Dai, Wenting Xu, Lulu Wang, Xiao Li, Xiaonan Sheng, Lei Zhu, Ye Li, Xinrui Dong, Weihang Zhou, Chenyu Han, Yan Mao, Linli Yao

Breast Cancer Res. 2023; 25: 90. Published online 2023 Jul 28. doi: 10.1186/s13058-023-01683-8

PMCID:: PMC10375677

Abstract Article PDF–5.2M

Select item 624928616.

miR-21 promotes EGF-induced pancreatic cancer cell proliferation by targeting Spry2

Qiuyan Zhao, Sumin Chen, Zhonglin Zhu, Lanting Yu, Yingchun Ren, Mingjie Jiang, Junyong Weng, Baiwen Li

Cell Death Dis. 2018 Dec; 9(12): 1157. Published online 2018 Nov 21. doi: 10.1038/s41419-018-1182-9

PMCID:: PMC6249286

Abstract Article PDF–5.5M

Select item 620136517.

Sprouty2 suppresses progression and correlates to favourable prognosis of intrahepatic cholangiocarcinoma via antagonizing FGFR2 signalling

Yun‐Fei Xu, Hong‐Da Liu, Zeng‐Li Liu, Chang Pan, Xiao‐Qing Yang, Shang‐Lei Ning, Zong‐Li Zhang, Sen Guo, Jin‐Ming Yu

J Cell Mol Med. 2018 Nov; 22(11): 5596–5606. Published online 2018 Aug 30. doi: 10.1111/jcmm.13833

PMCID:: PMC6201365

Abstract Article PDF–3.6M

Select item 607890718.

Regulation of vascular signalling by nuclear Sprouty2 in fetal lung epithelial cells: Implications for co-ordinated airway and vascular branching in lung development

David J. Walker, Stephen C. Land

Comp Biochem Physiol B Biochem Mol Biol. 2018 Oct; 224: 105–114. doi: 10.1016/j.cbpb.2018.01.007

PMCID:: PMC6078907

Abstract Article PDF–2.2M

Select item 583361419.

SPRY2 is a novel MET interactor that regulates metastatic potential and differentiation in rhabdomyosarcoma

Masum Saini, Aakanksha Verma, Sam J. Mathew

Cell Death Dis. 2018 Feb; 9(2): 237. Published online 2018 Feb 14. doi: 10.1038/s41419-018-0261-2

PMCID:: PMC5833614

Abstract Article PDF–3.0M

Select item 544002420.

A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response

Zachary Pappalardo, Deeksha Gambhir Chopra, Thomas G. Hennings, Hunter Richards, Justin Choe, Katherine Yang, Luc Baeyens, Kenny Ang, Steven Chen, Michelle Arkin, Michael S. German, Michael T. McManus, Gregory M. Ku

Diabetes. 2017 Jun; 66(6): 1703–1712. Published online 2017 Feb 28. doi: 10.2337/db16-0962

PMCID:: PMC5440024

Abstract Article PDF–1.5M

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PMC Links for Gene (Select 10253) (119)
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Bacillus subtilis strain PS-218 DNA gyrase subunit A (gyrA) gene, partial cds
Bacillus subtilis strain PS-218 DNA gyrase subunit A (gyrA) gene, partial cds
gi|387537406|gb|FJ172628.2|

Nucleotide
Bacillus subtilis strain PS-261 DNA gyrase subunit A (gyrA) gene, partial cds
Bacillus subtilis strain PS-261 DNA gyrase subunit A (gyrA) gene, partial cds
gi|387537412|gb|FJ172631.2|

Nucleotide

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