PMC Links for Gene (Select 10273) - PMC

Simon Ng, Shuhui Lim, Adrian Chong Nyi Sim, Ruban Mangadu, Ally Lau, Chunsheng Zhang, Sarah Bollinger Martinez, Arun Chandramohan, U-Ming Lim, Samantha Shu Wen Ho, Shih Chieh Chang, Pooja Gopal, Lewis Z. Hong, Adam Schwaid, Aaron Zefrin Fernandis, Andrey Loboda, Cai Li, Uyen Phan, Brian Henry, Anthony W. Partridge

Sci Rep. 2022; 12: 14087. Published online 2022 Aug 18. doi: 10.1038/s41598-022-18404-4

PMCID:: PMC9388626

Abstract Article PDF–3.3M

Select item 84634064.

A de novo STUB1 variant associated with an early adult-onset multisystemic ataxia phenotype

David Mengel, Andreas Traschütz, Selina Reich, Alejandra Leyva-Gutiérrez, Friedemann Bender, Stefan Hauser, Tobias B. Haack, Matthis Synofzik

J Neurol. 2021; 268(10): 3845–3851. Published online 2021 Apr 3. doi: 10.1007/s00415-021-10524-7

PMCID:: PMC8463406

Abstract Article PDF–1.0M

Select item 81992715.

Genetic Dominant Variants in STUB1, Segregating in Families with SCA48, Display In Vitro Functional Impairments Indistinctive from Recessive Variants Associated with SCAR16

Yasaman Pakdaman, Siren Berland, Helene J. Bustad, Sigrid Erdal, Bryony A. Thompson, Paul A. James, Kjersti N. Power, Ståle Ellingsen, Martin Krooni, Line I. Berge, Adrienne Sexton, Laurence A. Bindoff, Per M. Knappskog, Stefan Johansson, Ingvild Aukrust

Int J Mol Sci. 2021 Jun; 22(11): 5870. Published online 2021 May 30. doi: 10.3390/ijms22115870

PMCID:: PMC8199271

Abstract Article PDF–1.3M

Select item 75783546.

CHIP mutations affect the heat shock response differently in human fibroblasts and iPSC-derived neurons

S. Schuster, E. Heuten, A. Velic, J. Admard, M. Synofzik, S. Ossowski, B. Macek, S. Hauser, L. Schöls

Dis Model Mech. 2020 Oct 1; 13(10): dmm045096. Published online 2020 Oct 12. doi: 10.1242/dmm.045096

PMCID:: PMC7578354

Abstract Article

Select item 67940697.

Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis

Joao Vasco Ferreira, Ana Rosa Soares, José S. Ramalho, Teresa Ribeiro-Rodrigues, Catarina Máximo, Mónica Zuzarte, Henrique Girão, Paulo Pereira

PLoS One. 2019; 14(10): e0223790. Published online 2019 Oct 15. doi: 10.1371/journal.pone.0223790

PMCID:: PMC6794069

Abstract Article PDF–2.9M

Select item 62755908.

Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer

Eva Ruckova, Petr Muller, Rudolf Nenutil, Borivoj Vojtesek

Cell Mol Biol Lett. 2012 Sep; 17(3): 446–458. Published online 2012 Jun 5. doi: 10.2478/s11658-012-0021-8

PMCID:: PMC6275590

Summary PDF–497K

Select item 59558219.

Loss of the nuclear pool of ubiquitin ligase CHIP/STUB1 in breast cancer unleashes the MZF1-cathepsin pro-oncogenic program

Haitao Luan, Bhopal Mohapatra, Timothy A. Bielecki, Insha Mushtaq, Sameer Mirza, Tameka A. Jennings, Robert J. Clubb, Wei An, Dena Ahmed, Rokaya El Ansari, Matthew D. Storck, Nitish K. Mishra, Chittibabu Guda, Yuri M. Sheinin, Jane L. Meza, Srikumar Raja, Emad A. Rakha, Vimla Band, Hamid Band

Cancer Res. Author manuscript; available in PMC 2019 May 15.

Published in final edited form as: Cancer Res. 2018 May 15; 78(10): 2524–2535. Published online 2018 Mar 6. doi: 10.1158/0008-5472.CAN-16-2140

PMCID:: PMC5955821

Abstract Article PDF–1.2M

Select item 556371410.

Regulation of autophagic flux by CHIP

Dongkai Guo, Zheng Ying, Hongfeng Wang, Dong Chen, Feng Gao, Haigang Ren, Guanghui Wang

Neurosci Bull. 2015 Aug; 31(4): 469–479. Published online 2015 Jul 28. doi: 10.1007/s12264-015-1543-7

PMCID:: PMC5563714

Abstract Article PDF–831K

Select item 543197611.

Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase

Zhaofeng Ye, Patrick G. Needham, Samuel K. Estabrooks, Susan K. Whitaker, Brandon L. Garcia, Saurav Misra, Jeffrey L. Brodsky, Carlos J. Camacho

Sci Rep. 2017; 7: 1789. Published online 2017 May 11. doi: 10.1038/s41598-017-01880-4

PMCID:: PMC5431976

Abstract Article PDF–4.9M

Select item 530764312.

STUB1/CHIP mutations cause Gordon Holmes syndrome as part of a widespread multisystemic neurodegeneration: evidence from four novel mutations

Stefanie Nicole Hayer, Tine Deconinck, Benjamin Bender, Katrien Smets, Stephan Züchner, Selina Reich, Ludger Schöls, Rebecca Schüle, Peter De Jonghe, Jonathan Baets, Matthis Synofzik

Orphanet J Rare Dis. 2017; 12: 31. Published online 2017 Feb 13. doi: 10.1186/s13023-017-0580-x

PMCID:: PMC5307643

Abstract Article PDF–1.4M

Select item 497191613.

Prognostic value of the ubiquitin ligase carboxyl terminus of the Hsc70‐interacting protein in postmenopausal breast cancer

Sasagu Kurozumi, Yuri Yamaguchi, Shin‐ichi Hayashi, Hiromi Hiyoshi, Tetsuji Suda, Tatsuyuki Gohno, Hiroshi Matsumoto, Hiroyuki Takei, Jun Horiguchi, Izumi Takeyoshi, Tetsunari Oyama, Masafumi Kurosumi

Cancer Med. 2016 Aug; 5(8): 1873–1882. Published online 2016 Jun 23. doi: 10.1002/cam4.780

PMCID:: PMC4971916

Abstract Article PDF–460K

Select item 402183114.

Phenotype and frequency of STUB1 mutations: next-generation screenings in Caucasian ataxia and spastic paraplegia cohorts

Matthis Synofzik, Rebecca Schüle, Martin Schulze, Janina Gburek-Augustat, Roland Schweizer, Anja Schirmacher, Ingeborg Krägeloh-Mann, Michael Gonzalez, Peter Young, Stephan Züchner, Ludger Schöls, Peter Bauer

Orphanet J Rare Dis. 2014; 9: 57. Published online 2014 Apr 17. doi: 10.1186/1750-1172-9-57

PMCID:: PMC4021831

Abstract Article PDF–1.8M

Select item 16222515.

Overexpression of the Cochaperone CHIP Enhances Hsp70-Dependent Folding Activity in Mammalian Cells

Harm H. Kampinga, Bart Kanon, Florian A. Salomons, Alexander E. Kabakov, Cam Patterson

Mol Cell Biol. 2003 Jul; 23(14): 4948–4958. doi: 10.1128/MCB.23.14.4948-4958.2003

PMCID:: PMC162225

Abstract Article PDF–465K

Select item 1107345416.

CHIP induces ubiquitination and degradation of HMGB1 to regulate glycolysis in ovarian endometriosis

Yujun Sun, Qian Wang, Mengxue Wang, Fangyuan Sun, Pengyun Qiao, Aifang Jiang, Chune Ren, Zhenhai Yu, Tingting Yang

Cell Mol Life Sci. 2023 Jan; 80(1): 13. Published online 2022 Dec 19. doi: 10.1007/s00018-022-04637-z

Correction in:: Cell Mol Life Sci. 2023 Apr; 80(4): 94.

PMCID:: PMC11073454

Abstract Article PDF–13M

Select item 1051292817.

Degradation of CDK9 by Ubiquitin E3 Ligase STUB1 Regulates P-TEFb Level and Its Functions for Global Target Gene Expression within Mammalian Cells

Subham Basu, Arijit Nandy, Avik Ghosh, Dheerendra Pratap Mall, Debabrata Biswas

Mol Cell Biol. 2023; 43(9): 451–471. Published online 2023 Aug 11. doi: 10.1080/10985549.2023.2239694

PMCID:: PMC10512928

Abstract Article PDF–1.5M

Select item 919804818.

Ursodeoxycholic acid reduces antitumor immunosuppression by inducing CHIP-mediated TGF-β degradation

Yingying Shen, Chaojie Lu, Zhengbo Song, Chenxiao Qiao, Jiaoli Wang, Jinbiao Chen, Chengyan Zhang, Xianchang Zeng, Zeyu Ma, Tao Chen, Xu Li, Aifu Lin, Jufeng Guo, Jianli Wang, Zhijian Cai

Nat Commun. 2022; 13: 3419. Published online 2022 Jun 14. doi: 10.1038/s41467-022-31141-6

PMCID:: PMC9198048

Abstract Article PDF–6.2M

Select item 846693619.

Clinical and functional characterization of a novel STUB1 frameshift mutation in autosomal dominant spinocerebellar ataxia type 48 (SCA48)

Huan-Yun Chen, Chia-Lang Hsu, Han-Yi Lin, Yung-Feng Lin, Shih-Feng Tsai, Yu-Jung Ho, Ye-Ru Li, Jin-Wu Tsai, Shu-Chun Teng, Chin-Hsien Lin

J Biomed Sci. 2021; 28: 65. Published online 2021 Sep 26. doi: 10.1186/s12929-021-00763-1

PMCID:: PMC8466936

Abstract Article PDF–8.0M

Select item 845960020.

E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stress and promotes the prophylactic effects against diabetic cardiac damages

Ayaz Ali, Wei‐Wen Kuo, Chia‐Hua Kuo, Jeng‐Fan Lo, Michael Y. C. Chen, Jayasimha R. Daddam, Tsung‐Jung Ho, Vijaya Padma Viswanadha, Marthandam Asokan Shibu, Chih‐Yang Huang

Bioeng Transl Med. 2021 Sep; 6(3): e10234. Published online 2021 Jun 11. doi: 10.1002/btm2.10234

PMCID:: PMC8459600

Abstract Article PDF–64M

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E3 ubiquitin-protein ligase CHIP isoform b [Homo sapiens]
E3 ubiquitin-protein ligase CHIP isoform b [Homo sapiens]
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