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Select item 86269611.

PIAS3 suppresses damage in an Alzheimer’s disease cell model by inducing the STAT3-associated STAT3/Nestin/Nrf2/HO-1 pathway

Chen Li, Ruili Wang, Youyou Zhang, Chunting Hu, Qiaoya Ma

Mol Med. 2021; 27: 150. Published online 2021 Nov 27. doi: 10.1186/s10020-021-00410-3

PMCID:: PMC8626961

Abstract Article PDF–7.1M

Select item 50294302.

Protein Inhibitor of Activated STAT3 (PIAS3) Is Down-Regulated in Eutopic Endometrium of Women with Endometriosis

Jung-Yoon Yoo, Jae-Wook Jeong, Asgerally T. Fazleabas, Chandrakant Tayade, Steven L. Young, Bruce A. Lessey

Biol Reprod. 2016 Jul; 95(1): 11. Published online 2016 May 25. doi: 10.1095/biolreprod.115.137158

PMCID:: PMC5029430

Abstract Article PDF–1.0M

Select item 47144663.

Prognostic value of protein inhibitor of activated STAT3 in breast cancer patients receiving hormone therapy

Sheau-Fang Yang, Ming-Feng Hou, Fang-Ming Chen, Fu Ou-Yang, Yang-Chang Wu, Chee-Yin Chai, Yao-Tsung Yeh

BMC Cancer. 2016; 16: 20. Published online 2016 Jan 14. doi: 10.1186/s12885-016-2063-1

PMCID:: PMC4714466

Abstract Article PDF–1.0M

Select item 43809584.

PIAS3 expression in squamous cell lung cancer is low and predicts overall survival

Rime Abbas, Karen S McColl, Adam Kresak, Michael Yang, Yanwen Chen, Pingfu Fu, Gary Wildey, Afshin Dowlati

Cancer Med. 2015 Mar; 4(3): 325–332. Published online 2015 Jan 9. doi: 10.1002/cam4.372

PMCID:: PMC4380958

Abstract Article PDF–1010K

Select item 31040855.

Protein inhibitor of activated STAT3 expression in lung cancer

Amy Kluge, Snehal Dabir, Ilse Vlassenbroeck, Rosana Eisenberg, Afshin Dowlati

Mol Oncol. 2011 Jun; 5(3): 256–264. Published online 2011 Mar 30. doi: 10.1016/j.molonc.2011.03.004

PMCID:: PMC3104085

Abstract Article PDF–1.3M

Select item 27642526.

Cooperative Interaction between Protein Inhibitor of Activated STAT3 with EGFR blockade in Lung Cancer

Amy Kluge, Snehal Dabir, Jeffrey Kern, David Nethery, Balazs Halmos, Patrick Ma, Afshin Dowlati

Int J Cancer. Author manuscript; available in PMC 2010 Oct 1.

Published in final edited form as: Int J Cancer. 2009 Oct 1; 125(7): 1728–1734. doi: 10.1002/ijc.24553

PMCID:: PMC2764252

Abstract Article PDF–299K

Select item 17159297.

Overexpression of PIAS3 Suppresses Cell Growth and Restores the Drug Sensitivity of Human Lung Cancer Cells in Association with PI3-K/Akt Inactivation

Yoshitaka Ogata, Tadashi Osaki, Tetsuji Naka, Kota Iwahori, Mitsugi Furukawa, Izumi Nagatomo, Takashi Kijima, Toru Kumagai, Mitsuhiro Yoshida, Isao Tachibana, Ichiro Kawase

Neoplasia. 2006 Oct; 8(10): 817–825. doi: 10.1593/neo.06409

PMCID:: PMC1715929

Abstract Article PDF–369K

Select item 62752778.

Post‐transcriptional regulation of PIAS3 expression by miR‐18a in malignant mesothelioma

Tian He, Karen McColl, Nneha Sakre, Yanwen Chen, Gary Wildey, Afshin Dowlati

Mol Oncol. 2018 Dec; 12(12): 2124–2135. Published online 2018 Oct 23. doi: 10.1002/1878-0261.12386

PMCID:: PMC6275277

Abstract Article PDF–716K

Select item 59963659.

PIAS3-mediated feedback loops promote chronic colitis-associated malignant transformation

Junting Ma, Yaping Yang, Yong Fu, Feilong Guo, Xiaoyi Zhang, Shuke Xiao, Weiming Zhu, Zhen Huang, Junfeng Zhang, Jiangning Chen

Theranostics. 2018; 8(11): 3022–3037. Published online 2018 Apr 30. doi: 10.7150/thno.23046

PMCID:: PMC5996365

Abstract Article PDF–4.3M

Select item 590749310.

STAT3/PIAS3 levels serve as “early signature” genes in the development of high-grade serous carcinoma from the fallopian tube

Uksha Saini, Adrian A. Suarez, Shan Naidu, John J. Wallbillich, Kristin Bixel, Ross A. Wanner, Jason Bice, Raleigh D. Kladney, Jenny Lester, Beth Y. Karlan, Paul J. Goodfellow, David E. Cohn, Karuppaiyah Selvendiran

Cancer Res. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Cancer Res. 2018 Apr 1; 78(7): 1739–1750. Published online 2018 Jan 16. doi: 10.1158/0008-5472.CAN-17-1671

PMCID:: PMC5907493

Abstract Article PDF–3.5M

Select item 540571611.

Arsenic-induced sumoylation of Mus81 is involved in regulating genomic stability

Liyan Hu, Feikun Yang, Lou Lu, Wei Dai

Cell Cycle. 2017; 16(8): 802–811. Published online 2017 Mar 20. doi: 10.1080/15384101.2017.1302628

PMCID:: PMC5405716

Abstract Article PDF–912K

Select item 540056112.

The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness

Amrita Singh Chandhoke, Ayan Chanda, Kunal Karve, Lili Deng, Shirin Bonni

Oncotarget. 2017 Mar 28; 8(13): 21001–21014. Published online 2017 Feb 18. doi: 10.18632/oncotarget.15471

PMCID:: PMC5400561

Abstract Article PDF–14M

Select item 469716213.

The SUMO (Small Ubiquitin-like Modifier) Ligase PIAS3 Primes ATR for Checkpoint Activation

Ching-Shyi Wu, Lee Zou

J Biol Chem. 2016 Jan 1; 291(1): 279–290. Published online 2015 Nov 12. doi: 10.1074/jbc.M115.691170

PMCID:: PMC4697162

Abstract Article PDF–2.5M

Select item 419974714.

PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status

Snehal Dabir, Amy Kluge, Karen McColl, Yu Liu, Minh Lam, Balazs Halmos, Gary Wildey, Afshin Dowlati

Int J Cancer. Author manuscript; available in PMC 2014 Oct 16.

Published in final edited form as: Int J Cancer. 2014 Mar 1; 134(5): 1045–1054. Published online 2013 Sep 23. doi: 10.1002/ijc.28448

PMCID:: PMC4199747

Abstract Article PDF–898K

Select item 335928715.

NF-κB Repression by PIAS3 Mediated RelA SUMOylation

Yuangang Liu, Rebecca Bridges, Aaron Wortham, Molly Kulesz-Martin

PLoS One. 2012; 7(5): e37636. Published online 2012 May 23. doi: 10.1371/journal.pone.0037636

PMCID:: PMC3359287

Abstract Article PDF–1.6M

Select item 324813316.

Sumoylation of Vimentin₃₅₄ Is Associated with PIAS3 Inhibition of Glioma Cell Migration

Liming Wang, Jian Zhang, Sipra Banerjee, Laura Barnes, Venkateswara Sajja, Yiding Liu, Baochuan Guo, Yuping Du, Mukesh K. Agarwal, David N. Wald, Qin Wang, Jinbo Yang

Oncotarget. 2010 Nov; 1(7): 620–627. Published online 2010 Nov 11. doi: 10.18632/oncotarget.196

PMCID:: PMC3248133

Abstract Article PDF–1.2M

Select item 299231617.

SUMOylation of the GTPase Rac1 is required for optimal cell migration

Sonia Castillo-Lluva, Michael H. Tatham, Richard C. Jones, Ellis G. Jaffray, Ricky D. Edmondson, Ronald T. Hay, Angeliki Malliri

Nat Cell Biol. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: Nat Cell Biol. 2010 Nov; 12(11): 1078–1085. Published online 2010 Oct 10. doi: 10.1038/ncb2112

PMCID:: PMC2992316

Abstract Article PDF–2.0M

Select item 278323418.

Association and nuclear translocation of PIAS3-STAT3 complex is ligand and time dependent

Snehal Dabir, Amy Kluge, Afshin Dowlati

Mol Cancer Res. Author manuscript; available in PMC 2010 Nov 10.

Published in final edited form as: Mol Cancer Res. 2009 Nov; 7(11): 1854–1860. Published online 2009 Nov 10. doi: 10.1158/1541-7786.MCR-09-0313

PMCID:: PMC2783234

Abstract Article PDF–1.0M

Select item 226842819.

Identification of a New Site of Sumoylation on Tel (ETV6) Uncovers a PIAS-Dependent Mode of Regulating Tel Function

M. Guy Roukens, Mariam Alloul-Ramdhani, Alfred C. O. Vertegaal, Zeinab Anvarian, Crina I. A. Balog, André M. Deelder, Paul J. Hensbergen, David A. Baker

Mol Cell Biol. 2008 Apr; 28(7): 2342–2357. Published online 2008 Jan 22. doi: 10.1128/MCB.01159-07