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Select item 101826721.

SPON1 is an independent prognostic biomarker for ovarian cancer

Ryoya Miyakawa, Makoto Kobayashi, Kotaro Sugimoto, Yuta Endo, Manabu Kojima, Yasuyuki Kobayashi, Shigenori Furukawa, Tsuyoshi Honda, Takafumi Watanabe, Shigeyuki Asano, Shu Soeda, Yuko Hashimoto, Keiya Fujimori, Hideki Chiba

J Ovarian Res. 2023; 16: 95. Published online 2023 May 13. doi: 10.1186/s13048-023-01180-8

PMCID:: PMC10182672

Abstract Article PDF–2.0M

Select item 91365142.

Increased SPON1 promotes pancreatic ductal adenocarcinoma progression by enhancing IL‐6 trans‐signalling

Yanmiao Huo, Jian Yang, Jiahao Zheng, Dapeng Xu, Minwei Yang, Lingye Tao, Hongfei Yao, Xueliang Fu, Jianyu Yang, Dejun Liu, Rong Hua, Junfeng Zhang, Yongwei Sun, Lipeng Hu, Wei Liu

Cell Prolif. 2022 May; 55(5): e13237. Published online 2022 Apr 29. doi: 10.1111/cpr.13237

PMCID:: PMC9136514

Abstract Article PDF–5.4M

Select item 25612543.

The Crystal Structure of the Heparin-binding Reelin-N Domain of F-spondin

Kemin Tan, Mark Duquette, Jin-huan Liu, Jack Lawler, Jia-huai Wang

J Mol Biol. Author manuscript; available in PMC 2009 Sep 19.

Published in final edited form as: J Mol Biol. 2008 Sep 19; 381(5): 1213–1223. Published online 2008 Jun 24. doi: 10.1016/j.jmb.2008.06.045

PMCID:: PMC2561254

Abstract Article PDF–1.6M

Select item 68663094.

APOE influences working memory in non‐demented elderly through an interaction with SPON1 rs2618516

Zhen Liu, Xiangwei Dai, Wuhai Tao, Huilan Liu, He Li, Caishui Yang, Junying Zhang, Xin Li, Yaojing Chen, Chao Ma, Jing Pei, Haohao Mao, Kewei Chen, Zhanjun Zhang

Hum Brain Mapp. 2018 Jul; 39(7): 2859–2867. Published online 2018 Mar 24. doi: 10.1002/hbm.24045

PMCID:: PMC6866309

Abstract Article PDF–634K

Select item 48068485.

Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients

Hsin-Chou Yang, Shih-Kai Chu, Chieh-Liang Huang, Hsiang-Wei Kuo, Sheng-Chang Wang, Sheng-Wen Liu, Ing-Kang Ho, Yu-Li Liu

PLoS Genet. 2016 Mar; 12(3): e1005910. Published online 2016 Mar 24. doi: 10.1371/journal.pgen.1005910

PMCID:: PMC4806848

Abstract Article PDF–2.8M

Select item 38295926.

Experimental validation of 5 in-silico predicted glioma biomarkers

Rheal A. Towner, Randy L. Jensen, Brian Vaillant, Howard Colman, Debra Saunders, Cory B. Giles, Jonathan D. Wren

Neuro Oncol. 2013 Dec; 15(12): 1625–1634. Published online 2013 Oct 24. doi: 10.1093/neuonc/not124

PMCID:: PMC3829592

Abstract Article PDF–922K

Select item 26266157.

F-spondin, a neuroregulatory protein, is up-regulated in osteoarthritis and regulates cartilage metabolism via TGF-β activation

Mukundan G. Attur, Glyn D. Palmer, Hayf E. Al-Mussawir, Mandar Dave, Cristina C. Teixeira, Daniel B. Rifkin, C. Thomas G. Appleton, Frank Beier, Steven B. Abramson

FASEB J. 2009 Jan; 23(1): 79–89. doi: 10.1096/fj.08-114363

Correction in:: FASEB J. 2009 Aug; 23(8): 2790.

PMCID:: PMC2626615

Abstract Article

Select item 3569878.

Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage

Angela Ho, Thomas C. Südhof

Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8): 2548–2553. Published online 2004 Feb 17. doi: 10.1073/pnas.0308655100

PMCID:: PMC356987

Abstract Article PDF–452K

Select item 36069779.

Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity

Neda Jahanshad, Priya Rajagopalan, Xue Hua, Derrek P. Hibar, Talia M. Nir, Arthur W. Toga, Clifford R. Jack, Jr, Andrew J. Saykin, Robert C. Green, Michael W. Weiner, Sarah E. Medland, Grant W. Montgomery, Narelle K. Hansell, Katie L. McMahon, Greig I. de Zubicaray, Nicholas G. Martin, Margaret J. Wright, Paul M. Thompson, the Alzheimer’s Disease Neuroimaging Initiative, Michael Weiner, Paul Aisen, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, Jr., William Jagust, John Q. Trojanowski, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Enchi Liu, Robert C. Green, Tom Montine, Ronald Petersen, Paul Aisen, Anthony Gamst, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Laurel Beckett, Danielle Harvey, Anthony Gamst, Michael Donohue, John Kornak, Clifford R. Jack, Jr., Anders Dale, Matthew Bernstein, Joel Felmlee, Nick Fox, Paul Thompson, Norbert Schuff, Gene Alexander, Charles DeCarli, William Jagust, Dan Bandy, Robert A. Koeppe, Norm Foster, Eric M. Reiman, Kewei Chen, Chet Mathis, John Morris, Nigel J. Cairns, Lisa Taylor-Reinwald, J.Q. Trojanowki, Les Shaw, Virginia M.Y. Lee, Magdalena Korecka, Arthur W. Toga, Karen Crawford, Scott Neu, Andrew J. Saykin, Tatiana M. Foroud, Steven Potkin, Li Shen, Zaven Khachaturian, Richard Frank, Peter J. Snyder, Susan Molchan, Jeffrey Kaye, Joseph Quinn, Betty Lind, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Bryan M. Spann, James Brewer, Helen Vanderswag, Judith L. Heidebrink, Joanne L. Lord, Ronald Petersen, Kris Johnson, Rachelle S. Doody, Javier Villanueva-Meyer, Munir Chowdhury, Yaakov Stern, Lawrence S. Honig, Karen L. Bell, John C. Morris, Beau Ances, Maria Carroll, Sue Leon, Mark A. Mintun, Stacy Schneider, Daniel Marson, Randall Griffith, David Clark, Hillel Grossman, Effie Mitsis, Aliza Romirowsky, Leyla deToledo-Morrell, Raj C. Shah, Ranjan Duara, Daniel Varon, Peggy Roberts, Marilyn Albert, Chiadi Onyike, Stephanie Kielb, Henry Rusinek, Mony J. de Leon, Lidia Glodzik, Susan De Santi, P. Murali Doraiswamy, Jeffrey R. Petrella, R. Edward Coleman, Steven E. Arnold, Jason H. Karlawish, David Wolk, Charles D. Smith, Greg Jicha, Peter Hardy, Oscar L. Lopez, MaryAnn Oakley, Donna M. Simpson, Anton P. Porsteinsson, Bonnie S. Goldstein, Kim Martin, Kelly M. Makino, M. Saleem Ismail, Connie Brand, Ruth A. Mulnard, Gaby Thai, Catherine Mc-Adams-Ortiz, Kyle Womack, Dana Mathews, Mary Quiceno, Ramon Diaz-Arrastia, Richard King, Myron Weiner, Kristen Martin-Cook, Michael DeVous, Allan I. Levey, James J. Lah, Janet S. Cellar, Jeffrey M. Burns, Heather S. Anderson, Russell H. Swerdlow, Liana Apostolova, Po H. Lu, George Bartzokis, Daniel H.S. Silverman, Neill R. Graff-Radford, Francine Parfitt, Heather Johnson, Martin R. Farlow, Ann Marie Hake, Brandy R. Matthews, Scott Herring, Christopher H. van Dyck, Richard E. Carson, Martha G. MacAvoy, Howard Chertkow, Howard Bergman, Chris Hosein, Sandra Black, Bojana Stefanovic, Curtis Caldwell, Ging-Yuek Robin Hsiung, Howard Feldman, Benita Mudge, Michele Assaly, Andrew Kertesz, John Rogers, Dick Trost, Charles Bernick, Donna Munic, Diana Kerwin, Marek-Marsel Mesulam, Kristina Lipowski, Chuang-Kuo Wu, Nancy Johnson, Carl Sadowsky, Walter Martinez, Teresa Villena, Raymond Scott Turner, Kathleen Johnson, Brigid Reynolds, Reisa A. Sperling, Keith A. Johnson, Gad Marshall, Meghan Frey, Jerome Yesavage, Joy L. Taylor, Barton Lane, Allyson Rosen, Jared Tinklenberg, Marwan Sabbagh, Christine Belden, Sandra Jacobson, Neil Kowall, Ronald Killiany, Andrew E. Budson, Alexander Norbash, Patricia Lynn Johnson, Thomas O. Obisesan, Saba Wolday, Salome K. Bwayo, Alan Lerner, Leon Hudson, Paula Ogrocki, Evan Fletcher, Owen Carmichael, John Olichney, Charles DeCarli, Smita Kittur, Michael Borrie, T.-Y. Lee, Rob Bartha, Sterling Johnson, Sanjay Asthana, Cynthia M. Carlsson, Steven G. Potkin, Adrian Preda, Dana Nguyen, Pierre Tariot, Adam Fleisher, Stephanie Reeder, Vernice Bates, Horacio Capote, Michelle Rainka, Douglas W. Scharre, Maria Kataki, Earl A. Zimmerman, Dzintra Celmins, Alice D. Brown, Godfrey D. Pearlson, Karen Blank, Karen Anderson, Andrew J. Saykin, Robert B. Santulli, Eben S. Schwartz, Kaycee M. Sink, Jeff D. Williamson, Pradeep Garg, Franklin Watkins, Brian R. Ott, Henry Querfurth, Geoffrey Tremont, Stephen Salloway, Paul Malloy, Stephen Correia, Howard J. Rosen, Bruce L. Miller, Jacobo Mintzer, Crystal Flynn Longmire, Kenneth Spicer, Elizabeth Finger, Irina Rachinsky, John Rogers, Andrew Kertesz, Dick Drost

Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12): 4768–4773. Published online 2013 Feb 7. doi: 10.1073/pnas.1216206110

PMCID:: PMC3606977

Abstract Article PDF–690K

Select item 327569110.

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network (GOLDN)

Stella Aslibekyan, Edmond K. Kabagambe, Marguerite R. Irvin, Robert J. Straka, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jian Shen, Chao-Qiang Lai, Jose M. Ordovas, Donna K. Arnett

Pharmacogenet Genomics. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Pharmacogenet Genomics. 2012 Mar; 22(3): 191–197. doi: 10.1097/FPC.0b013e32834fdd41

PMCID:: PMC3275691

Abstract Article PDF–1.1M

Select item 388826211.

Genome-wide association study of ancestry-specific TB risk in the South African Coloured population

Emile R. Chimusa, Noah Zaitlen, Michelle Daya, Marlo Möller, Paul D. van Helden, Nicola J. Mulder, Alkes L. Price, Eileen G. Hoal

Hum Mol Genet. 2014 Feb 1; 23(3): 796–809. Published online 2013 Sep 20. doi: 10.1093/hmg/ddt462

PMCID:: PMC3888262

Abstract Article PDF–560K

Select item 376099512.

Genome Wide Association Study of the Rate of Cognitive Decline in Alzheimer’s Disease

Richard Sherva, Yorghos Tripodis, David Bennett, Lori B. Chibnik, Paul K. Crane, Philip de Jager, Lindsay A. Farrer, Andrew J. Saykin, Joshua Shulman, Robert C. Green, the Alzheimer’s Disease Neuroimaging Initiative

Alzheimers Dement. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Alzheimers Dement. 2014 Jan; 10(1): 10.1016/j.jalz.2013.01.008. Published online 2013 Mar 25. doi: 10.1016/j.jalz.2013.01.008

PMCID:: PMC3760995

Abstract Article PDF–589K

Select item 311768013.

The structure of the Ca²⁺-binding, glycosylated F-spondin domain of F-spondin - A C2-domain variant in an extracellular matrix protein

Kemin Tan, Jack Lawler

BMC Struct Biol. 2011; 11: 22. Published online 2011 May 10. doi: 10.1186/1472-6807-11-22

PMCID:: PMC3117680

Abstract Article PDF–2.6M

Select item 358276914.

CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression

Dong Young Kim, Eunju Kwon, Paul D. Hartley, David C. Crosby, Sumanjit Mann, Nevan J. Krogan, John D. Gross

Mol Cell. Author manuscript; available in PMC 2014 Feb 21.

Published in final edited form as: Mol Cell. 2013 Feb 21; 49(4): 632–644. Published online 2013 Jan 17. doi: 10.1016/j.molcel.2012.12.012

PMCID:: PMC3582769

Abstract Article PDF–4.5M

Select item 293811415.

Proteomics Characterization of Extracellular Space Components in the Human Aorta

Athanasios Didangelos, Xiaoke Yin, Kaushik Mandal, Mark Baumert, Marjan Jahangiri, Manuel Mayr

Mol Cell Proteomics. 2010 Sep; 9(9): 2048–2062. Published online 2010 Jun 15. doi: 10.1074/mcp.M110.001693

PMCID:: PMC2938114

Abstract Article PDF–700K

Select item 910523516.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 289646417.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 135612918.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 716998319.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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