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Select item 90575931.

HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation

Yanxin Fan, Marta Murgia, Monika I. Linder, Yoko Mizoguchi, Cong Wang, Marcin Łyszkiewicz, Natalia Ziȩtara, Yanshan Liu, Stephanie Frenz, Gabriela Sciuccati, Armando Partida-Gaytan, Zahra Alizadeh, Nima Rezaei, Peter Rehling, Sven Dennerlein, Matthias Mann, Christoph Klein

J Clin Invest. 2022 May 2; 132(9): e153153. Published online 2022 May 2. doi: 10.1172/JCI153153

PMCID:: PMC9057593

Abstract Article PDF–3.9M

Select item 86500402.

HAX1 maintains the glioma progression in hypoxia through promoting mitochondrial fission

Jinghui Lin, Yang Wang, Zhiqing Lin

J Cell Mol Med. 2021 Dec; 25(24): 11170–11184. Published online 2021 Nov 10. doi: 10.1111/jcmm.17038

PMCID:: PMC8650040

Abstract Article PDF–3.2M

Select item 76705673.

The interactome of multifunctional HAX1 protein suggests its role in the regulation of energy metabolism, de-aggregation, cytoskeleton organization and RNA-processing

Maciej Wakula, Anna Balcerak, Tymon Rubel, Mateusz Chmielarczyk, Ryszard Konopinski, Filip Lyczek, Ewa A. Grzybowska

Biosci Rep. 2020 Nov 27; 40(11): BSR20203094. Published online 2020 Nov 13. doi: 10.1042/BSR20203094

PMCID:: PMC7670567

Abstract Article PDF–1.8M

Select item 76060274.

HAX1 enhances the survival and metastasis of non‐small cell lung cancer through the AKT/mTOR and MDM2/p53 signaling pathway

Zhigang Liang, Yuan Zhong, Lifei Meng, Yi Chen, Yahui Liu, Aihua Wu, Xinjian Li, Mingsong Wang

Thorac Cancer. 2020 Nov; 11(11): 3155–3167. Published online 2020 Sep 14. doi: 10.1111/1759-7714.13634

PMCID:: PMC7606027

Abstract Article PDF–6.6M

Select item 68808825.

HAX1 impact on collective cell migration, cell adhesion, and cell shape is linked to the regulation of actomyosin contractility

Anna Balcerak, Alicja Trebinska-Stryjewska, Maciej Wakula, Mateusz Chmielarczyk, Urszula Smietanka, Tymon Rubel, Ryszard Konopinski, Ewelina Macech-Klicka, Renata Zub, Ewa Anna Grzybowska

Mol Biol Cell. 2019 Dec 1; 30(25): 3024–3036. doi: 10.1091/mbc.E19-05-0304

PMCID:: PMC6880882

Abstract Article PDF–3.5M

Select item 59443976.

Identification of the Functional Autophagy-Regulatory Domain in HCLS1-Associated Protein X-1 That Resists Against Oxidative Stress

Ying-Lan Li, Wen-Feng Cai, Lei Wang, Guan-Sheng Liu, Christian Paul, Lin Jiang, Boyu Wang, Xiang Gao, Yigang Wang, Shi-Zheng Wu

DNA Cell Biol. 2018 May 1; 37(5): 432–441. Published online 2018 May 1. doi: 10.1089/dna.2017.3873

PMCID:: PMC5944397

Abstract Article PDF–1.0M

Select item 58228727.

Critical Role of HAX-1 in Promoting Avian Influenza Virus Replication in Lung Epithelial Cells

Xue Li, Bingqian Qu, Ganlin He, Carol J. Cardona, Yongchun Song, Zheng Xing

Mediators Inflamm. 2018; 2018: 3586132. Published online 2018 Jan 16. doi: 10.1155/2018/3586132

PMCID:: PMC5822872

Abstract Article PDF–2.3M

Select item 56470368.

Abnormal expression of HAX-1 is associated with cellular proliferation and migration in human hypopharyngeal squamous cell carcinoma

Hao Wu, Jianqiu Chen, Qiang Wang, Yong Yin, Peng Da, Huijun Le, Zhenxin Zhang, Xiaoxia Qiu

Mol Med Rep. 2017 Oct; 16(4): 4664–4670. Published online 2017 Aug 3. doi: 10.3892/mmr.2017.7155

PMCID:: PMC5647036

Abstract Article PDF–1.3M

Select item 49143019.

Clinical and biological significance of HAX-1 overexpression in nasopharyngeal carcinoma

Bo You, Xiaolei Cao, Xiaoyi Shao, Haosheng Ni, Si Shi, Ying Shan, Zhifeng Gu, Yiwen You

Oncotarget. 2016 Mar 15; 7(11): 12505–12524. Published online 2016 Feb 9. doi: 10.18632/oncotarget.7274

PMCID:: PMC4914301

Abstract Article PDF–17M

Select item 455570510.

HAX-1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation

Yanxia Wang, Xin Huo, Zheng Cao, Hui Xu, Jian Zhu, Li Qian, Hong Fu, Bing Xu

Int J Clin Exp Pathol. 2015; 8(7): 8099–8106. Published online 2015 Jul 1.

PMCID:: PMC4555705

Abstract Article PDF–710K

Select item 452606211.

Expression of HAX-1 in colorectal cancer and its role in cancer cell growth

XIAOLAN LI, JIANWU JIANG, RUI YANG, XIANGSHANG XU, FAYONG HU, ANDING LIU, DEDING TAO, YAN LENG, JUNBO HU, JIANPING GONG, XUELAI LUO

Mol Med Rep. 2015 Sep; 12(3): 4071–4078. Published online 2015 Jun 11. doi: 10.3892/mmr.2015.3905

PMCID:: PMC4526062

Abstract Article PDF–1.2M

Select item 428189412.

HAX-1: A Novel P-Body Protein

Valery Zayat, Anna Balcerak, Jaroslaw Korczynski, Alicja Trebinska, Juliusz Wysocki, Elżbieta Sarnowska, Mateusz Chmielarczyk, Ewelina Macech, Ryszard Konopiński, Magdalena Dziembowska, Ewa A. Grzybowska

DNA Cell Biol. 2015 Jan 1; 34(1): 43–54. doi: 10.1089/dna.2014.2657

PMCID:: PMC4281894

Abstract Article PDF–1.4M

Select item 400792613.

Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis

Tatsuya Morishima, Ken-ichiro Watanabe, Akira Niwa, Hideyo Hirai, Satoshi Saida, Takayuki Tanaka, Itaru Kato, Katsutsugu Umeda, Hidefumi Hiramatsu, Megumu K. Saito, Kousaku Matsubara, Souichi Adachi, Masao Kobayashi, Tatsutoshi Nakahata, Toshio Heike

Haematologica. 2014 Jan; 99(1): 19–27. doi: 10.3324/haematol.2013.083873

PMCID:: PMC4007926

Abstract Article PDF–501K

Select item 361705714.

Analysis of HAX-1 gene expression in esophageal squamous cell carcinoma

Min Li, Yue Tang, Wenqiao Zang, Xiaoyan Xuan, Na Wang, Yunyun Ma, Yuanyuan Wang, Ziming Dong, Guoqiang Zhao

Diagn Pathol. 2013; 8: 47. Published online 2013 Mar 25. doi: 10.1186/1746-1596-8-47

PMCID:: PMC3617057

Abstract Article PDF–622K

Select item 353639715.

Cellular Protein HAX1 Interacts with the Influenza A Virus PA Polymerase Subunit and Impedes Its Nuclear Translocation

Wei-Bin Hsu, Jia-Ling Shih, Jie-Ru Shih, Jia-Ling Du, Shu-Chun Teng, Li-Min Huang, Won-Bo Wang

J Virol. 2013 Jan; 87(1): 110–123. doi: 10.1128/JVI.00939-12

PMCID:: PMC3536397

Abstract Article PDF–2.5M

Select item 343260716.

Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence

Bin Li, Qingsong Hu, Ranjie Xu, Haigang Ren, Erkang Fei, Dong Chen, Guanghui Wang

BMC Cell Biol. 2012; 13: 20. Published online 2012 Jul 24. doi: 10.1186/1471-2121-13-20

PMCID:: PMC3432607

Abstract Article PDF–2.0M

Select item 316478617.

HAX1 Mutations causing SCN and Neurological Disease Lead to Microstructural Abnormalities Revealed by Quantitative MRI

Kaan Boztug, Xiao-Qi Ding, Hans Hartmann, Lena Ziesenitz, Alejandro A. Schäffer, Jana Diestelhorst, Dietmar Pfeifer, Giridharan Appaswamy, Sonja Kehbel, Thorsten Simon, Abdullah Al Jefri, Heinrich Lanfermann, Christoph Klein

Am J Med Genet A. Author manuscript; available in PMC 2011 Sep 1.

Published in final edited form as: Am J Med Genet A. 2010 Dec; 152A(12): 3157–3163. doi: 10.1002/ajmg.a.33748

PMCID:: PMC3164786

Abstract Article PDF–1.7M

Select item 284367518.

HAX-1 overexpression, splicing and cellular localization in tumors

Alicja Trebinska, Alina Rembiszewska, Karolina Ciosek, Konrad Ptaszynski, Sebastian Rowinski, Jolanta Kupryjanczyk, Janusz A Siedlecki, Ewa A Grzybowska

BMC Cancer. 2010; 10: 76. Published online 2010 Mar 2. doi: 10.1186/1471-2407-10-76