PMC Links for Gene (Select 10590) - PMC

Select item 59225511.

Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction

Sara F. Hansson, Alex-Xianghua Zhou, Paulina Vachet, Jan W. Eriksson, Maria J. Pereira, Stanko Skrtic, Helen Jongsma Wallin, Anders Ericsson-Dahlstrand, Daniel Karlsson, Andrea Ahnmark, Maria Sörhede Winzell, Maria Chiara Magnone, Pia Davidsson

PLoS One. 2018; 13(4): e0196601. Published online 2018 Apr 27. doi: 10.1371/journal.pone.0196601

PMCID:: PMC5922551

Abstract Article PDF–9.0M

Select item 33410062.

Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation

Johannes Attems, Alan Alpar, Lauren Spence, Shane McParland, Mathias Heikenwalder, Mathias Uhlén, Heikki Tanila, Tomas G. M. Hökfelt, Tibor Harkany

Proc Natl Acad Sci U S A. 2012 Apr 17; 109(16): 6259–6264. Published online 2012 Apr 2. doi: 10.1073/pnas.1203843109

PMCID:: PMC3341006

Abstract Article PDF–1.8M

Select item 42021593.

Overexpression of secretagogin inhibits cell apoptosis and induces chemoresistance in small cell lung cancer under the regulation of miR-494

Yifeng Bai, Yanqin Sun, Juan Peng, Hongzhan Liao, Hongyi Gao, Ying Guo, Linlang Guo

Oncotarget. 2014 Sep; 5(17): 7760–7775. Published online 2014 Aug 4. doi: 10.18632/oncotarget.2305

PMCID:: PMC4202159

Abstract Article PDF–9.4M

Select item 69726064.

Differential expression of secretagogin immunostaining in the hippocampal formation and the entorhinal and perirhinal cortices of humans, rats, and mice

Silvia Tapia‐González, Ricardo Insausti, Javier DeFelipe

J Comp Neurol. 2020 Mar 1; 528(4): 523–541. Published online 2019 Oct 10. doi: 10.1002/cne.24773

PMCID:: PMC6972606

Abstract Article PDF–89M

Select item 35602795.

Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human

Tie-Jun Sten Shi, Qiong Xiang, Ming-Dong Zhang, Giuseppe Tortoriello, Henrik Hammarberg, Jan Mulder, Kaj Fried, Ludwig Wagner, Anna Josephson, Mathias Uhlén, Tibor Harkany, Tomas Hökfelt

Mol Pain. 2012; 8: 80. Published online 2012 Oct 29. doi: 10.1186/1744-8069-8-80

PMCID:: PMC3560279

Abstract Article PDF–2.0M

Select item 55100016.

A TRPV1‐to‐secretagogin regulatory axis controls pancreatic β‐cell survival by modulating protein turnover

Katarzyna Malenczyk, Fatima Girach, Edit Szodorai, Petter Storm, Åsa Segerstolpe, Giuseppe Tortoriello, Robert Schnell, Jan Mulder, Roman A Romanov, Erzsébet Borók, Fabiana Piscitelli, Vincenzo Di Marzo, Gábor Szabó, Rickard Sandberg, Stefan Kubicek, Gert Lubec, Tomas Hökfelt, Ludwig Wagner, Leif Groop, Tibor Harkany

EMBO J. 2017 Jul 14; 36(14): 2107–2125. Published online 2017 Jun 21. doi: 10.15252/embj.201695347

PMCID:: PMC5510001

Abstract Article PDF–2.7M

Select item 54282627.

SUMOylation and calcium control syntaxin-1A and secretagogin sequestration by tomosyn to regulate insulin exocytosis in human ß cells

Mourad Ferdaoussi, Jianyang Fu, Xiaoqing Dai, Jocelyn E. Manning Fox, Kunimasa Suzuki, Nancy Smith, Gregory Plummer, Patrick E. MacDonald

Sci Rep. 2017; 7: 248. Published online 2017 Mar 21. doi: 10.1038/s41598-017-00344-z

PMCID:: PMC5428262

Abstract Article PDF–3.0M

Select item 68399208.

SCGN deficiency results in colitis susceptibility

Luis F Sifuentes-Dominguez, Haiying Li, Ernesto Llano, Zhe Liu, Amika Singla, Ashish S Patel, Mahesh Kathania, Areen Khoury, Nicholas Norris, Jonathan J Rios, Petro Starokadomskyy, Jason Y Park, Purva Gopal, Qi Liu, Shuai Tan, Lillienne Chan, Theodora Ross, Steven Harrison, K Venuprasad, Linda A Baker, Da Jia, Ezra Burstein

eLife. 2019; 8: e49910. Published online 2019 Oct 30. doi: 10.7554/eLife.49910

PMCID:: PMC6839920

Abstract Article PDF–1.9M

Select item 53476349.

Secretagogin-dependent matrix metalloprotease-2 release from neurons regulates neuroblast migration

János Hanics, Edit Szodorai, Giuseppe Tortoriello, Katarzyna Malenczyk, Erik Keimpema, Gert Lubec, Zsófia Hevesi, Mirjam I. Lutz, Márk Kozsurek, Zita Puskár, Zsuzsanna E. Tóth, Ludwig Wagner, Gábor G. Kovács, Tomas G. M. Hökfelt, Tibor Harkany, Alán Alpár

Proc Natl Acad Sci U S A. 2017 Mar 7; 114(10): E2006–E2015. Published online 2017 Feb 21. doi: 10.1073/pnas.1700662114

PMCID:: PMC5347634

Abstract Article PDF–3.3M

Select item 980610910.

SCGN deficiency is a risk factor for autism spectrum disorder

Zhe Liu, Shuai Tan, Lianyu Zhou, Li Chen, Mingfeng Liu, Wang Wang, Yingying Tang, Qin Yang, Sensen Chi, Peiyan Jiang, Yue Zhang, Yonghua Cui, Junhong Qin, Xiao Hu, Shenglong Li, Qi Liu, Lu Chen, Song Li, Ezra Burstein, Wei Li, Xiaohu Zhang, Xianming Mo, Da Jia

Signal Transduct Target Ther. 2023; 8: 3. Published online 2023 Jan 2. doi: 10.1038/s41392-022-01225-2

PMCID:: PMC9806109

Abstract Article PDF–4.2M

Select item 291775411.

Secretagogin is a Ca²⁺-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon

Jan Mulder, Lauren Spence, Giuseppe Tortoriello, Jennifer A. DiNieri, Mathias Uhlén, Bo Shui, Michael I. Kotlikoff, Yuchio Yanagawa, Fabienne Aujard, Tomas Hökfelt, Yasmin L. Hurd, Tibor Harkany

Eur J Neurosci. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Eur J Neurosci. 2010 Jun; 31(12): 2166–2177. Published online 2010 Jun 7. doi: 10.1111/j.1460-9568.2010.07275.x

PMCID:: PMC2917754

Abstract Article PDF–4.8M

Select item 268394012.

Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations

Melanie Kolz, Toby Johnson, Serena Sanna, Alexander Teumer, Veronique Vitart, Markus Perola, Massimo Mangino, Eva Albrecht, Chris Wallace, Martin Farrall, Åsa Johansson, Dale R. Nyholt, Yurii Aulchenko, Jacques S. Beckmann, Sven Bergmann, Murielle Bochud, Morris Brown, Harry Campbell, for the EUROSPAN Consortium, John Connell, Anna Dominiczak, Georg Homuth, Claudia Lamina, Mark I. McCarthy, for the ENGAGE Consortium, Thomas Meitinger, Vincent Mooser, Patricia Munroe, Matthias Nauck, John Peden, Holger Prokisch, Perttu Salo, Veikko Salomaa, Nilesh J. Samani, David Schlessinger, Manuela Uda, Uwe Völker, Gérard Waeber, Dawn Waterworth, Rui Wang-Sattler, Alan F. Wright, Jerzy Adamski, John B. Whitfield, Ulf Gyllensten, James F. Wilson, Igor Rudan, Peter Pramstaller, Hugh Watkins, for the PROCARDIS Consortium, Angela Doering, H.-Erich Wichmann, for the KORA Study, Tim D. Spector, Leena Peltonen, Henry Völzke, Ramaiah Nagaraja, Peter Vollenweider, Mark Caulfield, for the WTCCC, Thomas Illig, Christian Gieger

PLoS Genet. 2009 Jun; 5(6): e1000504. Published online 2009 Jun 5. doi: 10.1371/journal.pgen.1000504

PMCID:: PMC2683940

Abstract Article PDF–486K

Select item 266805313.

Variants in TF and HFE Explain ∼40% of Genetic Variation in Serum-Transferrin Levels

Beben Benyamin, Allan F. McRae, Gu Zhu, Scott Gordon, Anjali K. Henders, Aarno Palotie, Leena Peltonen, Nicholas G. Martin, Grant W. Montgomery, John B. Whitfield, Peter M. Visscher

Am J Hum Genet. 2009 Jan 9; 84(1): 60–65. doi: 10.1016/j.ajhg.2008.11.011

PMCID:: PMC2668053

Abstract Article PDF–618K

Select item 461721114.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 716998315.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011