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Items: 1 to 20 of 110

1.
Downregulation of Dihydrotestosterone and Estradiol Levels by HEXIM1
Fitya Mozar, Vikas Sharma, Shashank Gorityala, Jeffrey M Albert, Yan Xu, Monica M Montano
Endocrinology. 2022 Jan; 163(1): bqab236. Published online 2021 Nov 19. doi: 10.1210/endocr/bqab236
PMCID:
PMC8645165
AbstractArticle
2.
HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer
Hengyi Shao, Qingwei Zhu, Huasong Lu, Amanda Chang, Carol Gao, Qiang Zhou, Kunxin Luo
Mol Biol Cell. 2020 Aug 1; 31(17): 1867–1878. doi: 10.1091/mbc.E19-12-0704
PMCID:
PMC7525814
AbstractArticlePDF–2.0M
3.
Structural transitions in the RNA 7SK 5′ hairpin and their effect on HEXIM binding
Konstantin Röder, Guillaume Stirnemann, Anne-Catherine Dock-Bregeon, David J Wales, Samuela Pasquali
Nucleic Acids Res. 2020 Jan 10; 48(1): 373–389. Published online 2019 Nov 16. doi: 10.1093/nar/gkz1071
PMCID:
PMC7145557
AbstractArticlePDF–6.6M
4.
Hexim1, an RNA-controlled protein hub
Annemieke A. Michels, Olivier Bensaude
Transcription. 2018; 9(4): 262–271. Published online 2018 Feb 23. doi: 10.1080/21541264.2018.1429836
PMCID:
PMC6104690
AbstractArticlePDF–858K
5.
HEXIM1 plays a critical role in the inhibition of the androgen receptor by anti-androgens
I-Ju Yeh, Kyung Song, Bryan M. Wittmann, Xiaodong Bai, David Danielpour, Monica M. Montano
Biochem J. Author manuscript; available in PMC 2017 Nov 28.
Published in final edited form as: Biochem J. 2014 Sep 1; 462(2): 315–327. doi: 10.1042/BJ20140174
PMCID:
PMC5705236
AbstractArticlePDF–863K
6.
HMBA is a putative HSP70 activator stimulating HEXIM1 expression that is down-regulated by estrogen
Rati Lama, Chunfang Gan, Nethrie Idippily, Viharika Bobba, David Danielpour, Monica Montano, Bin Su
J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2017 Nov 22.
Published in final edited form as: J Steroid Biochem Mol Biol. 2017 Apr; 168: 91–101. Published online 2017 Feb 14. doi: 10.1016/j.jsbmb.2017.02.008
PMCID:
PMC5699885
AbstractArticlePDF–1.3M
7.
Induction of HEXIM1 activities by HMBA derivative 4a1: functional consequences and mechanism
Wannarasmi Ketchart, I-Ju Yeh, Haoyan Zhou, Praveena Thiagarajan, Justin Lathia, Ofer Reizes, Agata Exner, Bin Su, Monica M. Montano
Cancer Lett. Author manuscript; available in PMC 2017 Aug 28.
Published in final edited form as: Cancer Lett. 2016 Aug 28; 379(1): 60–69. Published online 2016 May 26. doi: 10.1016/j.canlet.2016.05.029
PMCID:
PMC4988685
AbstractArticlePDF–968K
8.
HEXIM1 Induces Differentiation of Human Pluripotent Stem Cells
Vanessa Ding, Qiao Jing Lew, Kai Ling Chu, Subaashini Natarajan, Vikneswari Rajasegaran, Meera Gurumurthy, Andre B. H. Choo, Sheng-Hao Chao
PLoS One. 2013; 8(8): e72823. Published online 2013 Aug 20. doi: 10.1371/journal.pone.0072823
PMCID:
PMC3748041
AbstractArticlePDF–699K
9.
HEXIM1 regulates E2/ERα-mediated expression of Cyclin D1 in mammary cells via modulation of P-TEFb
Ndiya Ogba, Laura J. Chaplin, Yong Qiu Doughman, Koh Fujinaga, Monica M. Montano
Cancer Res. Author manuscript; available in PMC 2010 Mar 3.
Published in final edited form as: Cancer Res. 2008 Sep 1; 68(17): 7015–7024. doi: 10.1158/0008-5472.CAN-08-0814
PMCID:
PMC2831806
AbstractArticlePDF–1.0M
10.
HMBA Releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and Activates HIV Transcription
Xavier Contreras, Matjaz Barboric, Tina Lenasi, B. Matija Peterlin
PLoS Pathog. 2007 Oct; 3(10): e146. Published online 2007 Oct 12. doi: 10.1371/journal.ppat.0030146
PMCID:
PMC2014796
AbstractArticlePDF–607K
11.
Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells
Monica M. Montano, I-Ju Yeh, Yinghua Chen, Chris Hernandez, Janna G. Kiselar, Maria de la Fuente, Adriane M. Lawes, Marvin T. Nieman, Philip D. Kiser, James Jacobberger, Agata A. Exner, Matthew C. Lawes
Breast Cancer Res. 2019; 21: 138. Published online 2019 Dec 5. doi: 10.1186/s13058-019-1228-7
PMCID:
PMC6896798
AbstractArticlePDF–2.2M
12.
Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer
I-Ju Yeh, Emily Esakov, Justin D. Lathia, Masaru Miyagi, Ofer Reizes, Monica M. Montano
Sci Rep. 2019; 9: 17663. Published online 2019 Nov 27. doi: 10.1038/s41598-019-54184-0
PMCID:
PMC6881367
AbstractArticlePDF–4.2M
13.
HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb
Alessandro Furlan, Mariano Gonzalez-Pisfil, Aymeric Leray, Dorian Champelovier, Mélanie Henry, Corentin Le Nézet, Oliver Bensaude, Marc Lefranc, Thorsten Wohland, Bernard Vandenbunder, Gabriel Bidaux, Laurent Héliot
Biophys J. 2019 Nov 5; 117(9): 1615–1625. Published online 2019 Sep 20. doi: 10.1016/j.bpj.2019.09.019
PMCID:
PMC6838758
AbstractArticlePDF–1.0M
14.
BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
Akhil Bowry, Ann Liza Piberger, Patricia Rojas, Marco Saponaro, Eva Petermann
Cell Rep. 2018 Nov 20; 25(8): 2061–2069.e4. Published online 2018 Nov 20. doi: 10.1016/j.celrep.2018.10.079
PMCID:
PMC6280123
AbstractArticle
15.
Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells
Min Huang, Jacqueline S. Garcia, Daniel Thomas, Li Zhu, Le Xuan Truong Nguyen, Steven M. Chan, Ravindra Majeti, Bruno C. Medeiros, Beverly S. Mitchell
Oncotarget. 2016 Nov 15; 7(46): 74917–74930. Published online 2016 Oct 6. doi: 10.18632/oncotarget.12493
PMCID:
PMC5342712
AbstractArticlePDF–8.4M
16.
Cardiomyocyte-Specific Overexpression of HEXIM1 Prevents Right Ventricular Hypertrophy in Hypoxia-Induced Pulmonary Hypertension in Mice
Noritada Yoshikawa, Noriaki Shimizu, Takako Maruyama, Motoaki Sano, Tomohiro Matsuhashi, Keiichi Fukuda, Masaharu Kataoka, Toru Satoh, Hidenori Ojima, Takashi Sawai, Chikao Morimoto, Akiko Kuribara, Osamu Hosono, Hirotoshi Tanaka
PLoS One. 2012; 7(12): e52522. Published online 2012 Dec 31. doi: 10.1371/journal.pone.0052522
PMCID:
PMC3534105
AbstractArticlePDF–2.4M
17.
The Transcription-Dependent Dissociation of P-TEFb-HEXIM1-7SK RNA Relies upon Formation of hnRNP-7SK RNA Complexes
Charlotte Barrandon, François Bonnet, Van Trung Nguyen, Valérie Labas, Olivier Bensaude
Mol Cell Biol. 2007 Oct; 27(20): 6996–7006. Published online 2007 Aug 20. doi: 10.1128/MCB.00975-07
PMCID:
PMC2168891
AbstractArticlePDF–632K
18.
Regulation of Polymerase II Transcription by 7SK snRNA: Two Distinct RNA Elements Direct P-TEFb and HEXIM1 Binding
Sylvain Egloff, Elodie Van Herreweghe, Tamás Kiss
Mol Cell Biol. 2006 Jan; 26(2): 630–642. doi: 10.1128/MCB.26.2.630-642.2006
PMCID:
PMC1346915
AbstractArticlePDF–945K
19.
HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b
Noriaki Shimizu, Rika Ouchida, Noritada Yoshikawa, Tetsuya Hisada, Hajime Watanabe, Kensaku Okamoto, Masatoshi Kusuhara, Hiroshi Handa, Chikao Morimoto, Hirotoshi Tanaka
Proc Natl Acad Sci U S A. 2005 Jun 14; 102(24): 8555–8560. Published online 2005 Jun 7. doi: 10.1073/pnas.0409863102
PMCID:
PMC1150813
AbstractArticlePDF–628K
20.
A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis
Nanhai He, Nadine S. Jahchan, Eunmee Hong, Qiang Li, Mark A. Bayfield, Richard J. Maraia, Kunxin Luo, Qiang Zhou
Mol Cell. Author manuscript; available in PMC 2018 Nov 16.
Published in final edited form as: Mol Cell. 2008 Mar 14; 29(5): 588–599. Published online 2008 Jan 31. doi: 10.1016/j.molcel.2008.01.003
PMCID:
PMC6239424
AbstractArticlePDF–1.9M

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