PMC Links for Gene (Select 10636) - PMC

Peter A. Friedman, W. Bruce Sneddon, Tatyana Mamonova, Carolina Montanez-Miranda, Suneela Ramineni, Nicholas H. Harbin, Katherine E. Squires, Julia V. Gefter, Clara E. Magyar, David R. Emlet, John R. Hepler

J Biol Chem. 2022 May; 298(5): 101836. Published online 2022 Mar 17. doi: 10.1016/j.jbc.2022.101836

PMCID:: PMC9035407

Abstract Article PDF–4.0M

Select item 79490465.

Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons

Katherine E. Squires, Kyle J. Gerber, Matthew C. Tillman, Daniel J. Lustberg, Carolina Montañez-Miranda, Meilan Zhao, Suneela Ramineni, Christopher D. Scharer, Ramendra N. Saha, Feng-Jue Shu, Jason P. Schroeder, Eric A. Ortlund, David Weinshenker, Serena M. Dudek, John R. Hepler

J Biol Chem. 2021 Jan-Jun; 296: 100024. Published online 2020 Nov 22. doi: 10.1074/jbc.RA120.016009

PMCID:: PMC7949046

Abstract Article PDF–3.7M

Select item 68728756.

The rs1256328 (ALPL) and rs12654812 (RGS14) Polymorphisms are Associated with Susceptibility to Calcium Nephrolithiasis in a Taiwanese population

Wei-Chiao Chen, Wan-Hsuan Chou, Hou-Wei Chu, Chi-Chen Huang, Xiao Liu, Wei-Pin Chang, Yii-Her Chou, Wei-Chiao Chang

Sci Rep. 2019; 9: 17296. Published online 2019 Nov 21. doi: 10.1038/s41598-019-53261-8

PMCID:: PMC6872875

Abstract Article PDF–1.1M

Select item 31812077.

Regulator of G protein signaling-14 protein modulates Ca²⁺ influx via Cav1 channels

Elisa Martín-Montañez, Maria José Acevedo, Juan Félix López-Téllez, R. Scott Duncan, Antonio González Mateos, José Pavía, Peter Koulen, Zafar U. Khan

Neuroreport. Author manuscript; available in PMC 2011 Nov 17.

Published in final edited form as: Neuroreport. 2010 Nov 17; 21(16): 1034–1039. doi: 10.1097/WNR.0b013e32833f7b7b

PMCID:: PMC3181207

Abstract Article PDF–203K

Select item 61712678.

Genetic Variants Associated with Circulating Fibroblast Growth Factor 23

Cassianne Robinson-Cohen, Traci M. Bartz, Dongbing Lai, T. Alp Ikizler, Munro Peacock, Erik A. Imel, Erin D. Michos, Tatiana M. Foroud, Kristina Akesson, Kent D. Taylor, Linnea Malmgren, Kunihiro Matsushita, Maria Nethander, Joel Eriksson, Claes Ohlsson, Daniel Mellström, Myles Wolf, Osten Ljunggren, Fiona McGuigan, Jerome I. Rotter, Magnus Karlsson, Michael J. Econs, Joachim H. Ix, Pamela L. Lutsey, Bruce M. Psaty, Ian H. de Boer, Bryan R. Kestenbaum

J Am Soc Nephrol. 2018 Oct; 29(10): 2583–2592. Published online 2018 Sep 14. doi: 10.1681/ASN.2018020192

PMCID:: PMC6171267

Abstract Article

Select item 59516389.

Regulator of G Protein Signaling 14 (RGS14) is Expressed Pre- and Postsynaptically in Neurons of Hippocampus, Basal Ganglia, and Amygdala of Monkey and Human Brain

Katherine E Squires, Kyle J Gerber, Jean-Francois Pare, Mary Rose Branch, Yoland Smith, John R Hepler

Brain Struct Funct. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Brain Struct Funct. 2018 Jan; 223(1): 233–253. Published online 2017 Aug 3. doi: 10.1007/s00429-017-1487-y

PMCID:: PMC5951638

Abstract Article PDF–1.5M

Select item 290344510.

Computational Design of Second-Site Suppressor Mutations at Protein-Protein Interfaces

Deanne W. Sammond, Ziad M. Eletr, Carrie Purbeck, Brian Kuhlman

Proteins. Author manuscript; available in PMC 2011 Mar 1.

Published in final edited form as: Proteins. 2010 Mar; 78(4): 1055–1065. doi: 10.1002/prot.22631

PMCID:: PMC2903445

Abstract Article PDF–1.9M

Select item 268232711.

Structure-based Protocol for Identifying Mutations that Enhance Protein-Protein Binding Affinities

Deanne W. Sammond, Ziad M. Eletr, Carrie Purbeck, Randall J. Kimple, David P. Siderovski, Brian Kuhlman

J Mol Biol. Author manuscript; available in PMC 2009 May 14.

Published in final edited form as: J Mol Biol. 2007 Aug 31; 371(5): 1392–1404. Published online 2007 Jun 8. doi: 10.1016/j.jmb.2007.05.096

PMCID:: PMC2682327

Abstract Article PDF–1.5M

Select item 279508312.

RGS14 IS A MULTIFUNCTIONAL SCAFFOLD THAT INTEGRATES G PROTEIN AND RAS/RAF MAPKINASE SIGNALLING PATHWAYS

Feng-jue Shu, Suneela Ramineni, John R. Hepler

Cell Signal. Author manuscript; available in PMC 2011 Mar 1.

Published in final edited form as: Cell Signal. 2010 Mar; 22(3): 366–376. doi: 10.1016/j.cellsig.2009.10.005

PMCID:: PMC2795083

Abstract Article PDF–1.6M

Select item 514695413.

Regulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at Gα_i/o

Jae-Pyo Jeon, Dhananjay P. Thakur, Jin-bin Tian, Insuk So, Michael X. Zhu

Biochem J. Author manuscript; available in PMC 2017 May 15.

Published in final edited form as: Biochem J. 2016 May 15; 473(10): 1379–1390. Published online 2016 Mar 17. doi: 10.1042/BCJ20160214

PMCID:: PMC5146954

Abstract Article PDF–1.0M

Select item 320740014.

G Protein-coupled Receptors and Resistance to Inhibitors of Cholinesterase-8A (Ric-8A) Both Regulate the Regulator of G Protein Signaling 14 (RGS14)·Gα_i1 Complex in Live Cells

Christopher P. Vellano, Ellen M. Maher, John R. Hepler, Joe B. Blumer

J Biol Chem. 2011 Nov 4; 286(44): 38659–38669. Published online 2011 Aug 31. doi: 10.1074/jbc.M111.274928

PMCID:: PMC3207400

Abstract Article PDF–2.4M

Select item 344237615.

The GTPase-deficient Rnd Proteins Are Stabilized by Their Effectors

Liuh Ling Goh, Ed Manser

J Biol Chem. 2012 Sep 7; 287(37): 31311–31320. Published online 2012 Jul 17. doi: 10.1074/jbc.M111.327056

PMCID:: PMC3442376

Abstract Article PDF–2.2M

Select item 206444416.

Localization of G_iα proteins in the centrosomes and at the midbody: implication for their role in cell division

Hyeseon Cho, John H. Kehrl

J Cell Biol. 2007 Jul 16; 178(2): 245–255. doi: 10.1083/jcb.200604114

PMCID:: PMC2064444

Abstract Article PDF–2.3M

Select item 329153817.

A Genome-Wide Association Study of Nephrolithiasis in the Japanese Population Identifies Novel Susceptible Loci at 5q35.3, 7p14.3, and 13q14.1

Yuji Urabe, Chizu Tanikawa, Atsushi Takahashi, Yukinori Okada, Takashi Morizono, Tatsuhiko Tsunoda, Naoyuki Kamatani, Kenjiro Kohri, Kazuaki Chayama, Michiaki Kubo, Yusuke Nakamura, Koichi Matsuda

PLoS Genet. 2012 Mar; 8(3): e1002541. Published online 2012 Mar 1. doi: 10.1371/journal.pgen.1002541

PMCID:: PMC3291538

Abstract Article PDF–184K

Select item 295093318.

Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma

Jianming Wang, Scott M. Lippman, J.Jack Lee, Hushan Yang, Fadlo R. Khuri, Edward Kim, Jie Lin, David W. Chang, Reuben Lotan, Waun K. Hong, Xifeng Wu

Carcinogenesis. 2010 Oct; 31(10): 1755–1761. Published online 2010 Jul 12. doi: 10.1093/carcin/bgq138

PMCID:: PMC2950933

Abstract Article PDF–131K

Select item 377800419.

Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations

Conall M. O'Seaghdha, Hongsheng Wu, Qiong Yang, Karen Kapur, Idris Guessous, Annie Mercier Zuber, Anna Köttgen, Candice Stoudmann, Alexander Teumer, Zoltán Kutalik, Massimo Mangino, Abbas Dehghan, Weihua Zhang, Gudny Eiriksdottir, Guo Li, Toshiko Tanaka, Laura Portas, Lorna M. Lopez, Caroline Hayward, Kurt Lohman, Koichi Matsuda, Sandosh Padmanabhan, Dmitri Firsov, Rossella Sorice, Sheila Ulivi, A. Catharina Brockhaus, Marcus E. Kleber, Anubha Mahajan, Florian D. Ernst, Vilmundur Gudnason, Lenore J. Launer, Aurelien Mace, Eric Boerwinckle, Dan E. Arking, Chizu Tanikawa, Yusuke Nakamura, Morris J. Brown, Jean-Michel Gaspoz, Jean-Marc Theler, David S. Siscovick, Bruce M. Psaty, Sven Bergmann, Peter Vollenweider, Veronique Vitart, Alan F. Wright, Tatijana Zemunik, Mladen Boban, Ivana Kolcic, Pau Navarro, Edward M. Brown, Karol Estrada, Jingzhong Ding, Tamara B. Harris, Stefania Bandinelli, Dena Hernandez, Andrew B. Singleton, Giorgia Girotto, Daniela Ruggiero, Adamo Pio d'Adamo, Antonietta Robino, Thomas Meitinger, Christa Meisinger, Gail Davies, John M. Starr, John C. Chambers, Bernhard O. Boehm, Bernhard R. Winkelmann, Jie Huang, Federico Murgia, Sarah H. Wild, Harry Campbell, Andrew P. Morris, Oscar H. Franco, Albert Hofman, Andre G. Uitterlinden, Fernando Rivadeneira, Uwe Völker, Anke Hannemann, Reiner Biffar, Wolfgang Hoffmann, So–Youn Shin, Pierre Lescuyer, Hughes Henry, Claudia Schurmann, The SUNLIGHT consortium, The GEFOS consortium, Patricia B. Munroe, Paolo Gasparini, Nicola Pirastu, Marina Ciullo, Christian Gieger, Winfried März, Lars Lind, Tim D. Spector, Albert V. Smith, Igor Rudan, James F. Wilson, Ozren Polasek, Ian J. Deary, Mario Pirastu, Luigi Ferrucci, Yongmei Liu, Bryan Kestenbaum, Jaspal S. Kooner, Jacqueline C. M. Witteman, Matthias Nauck, W. H. Linda Kao, Henri Wallaschofski, Olivier Bonny, Caroline S. Fox, Murielle Bochud

PLoS Genet. 2013 Sep; 9(9): e1003796. Published online 2013 Sep 19. doi: 10.1371/journal.pgen.1003796

PMCID:: PMC3778004

Abstract Article PDF–797K

Select item 122122020.

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao.

S Traver, C Bidot, N Spassky, T Baltauss, M F De Tand, J L Thomas, B Zalc, I Janoueix-Lerosey, J D Gunzburg

Biochem J. 2000 Aug 15; 350(Pt 1): 19–29.

PMCID:: PMC1221220

Summary PDF–289K

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