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Items: 1 to 20 of 53

1.
Identification of regulatory variants of carboxylesterase 1 (CES1): A proof‐of‐concept study for the application of the Allele‐Specific Protein Expression (ASPE) assay in identifying cis‐acting regulatory genetic polymorphisms
Lucy Her, Jian Shi, Xinwen Wang, Bing He, Logan S. Smith, Hui Jiang, Hao‐Jie Zhu
Proteomics. 2023 Jan; 23(1): 2200176. Published online 2022 Dec 7. doi: 10.1002/pmic.202200176
PMCID:
PMC10077986
AbstractArticlePDF–1.1M
2.
The Influence of Structural Variants of the CES1 Gene on the Pharmacokinetics of Enalapril, Presumably Due to Linkage Disequilibrium with the Intronic rs2244613
Anna Ikonnikova, Ruslan Kazakov, Tatiana Rodina, Artem Dmitriev, Evgeniy Melnikov, Alexander Zasedatelev, Tatiana Nasedkina
Genes (Basel) 2022 Dec; 13(12): 2225. Published online 2022 Nov 27. doi: 10.3390/genes13122225
PMCID:
PMC9778508
AbstractArticlePDF–568K
3.
Carboxylesterase-1 Assisted Targeting of HDAC Inhibitors to Mononuclear Myeloid Cells in Inflammatory Bowel Disease
Ahmed M I Elfiky, Mohammed Ghiboub, Andrew Y F Li Yim, Ishtu L Hageman, Jan Verhoeff, Manon de Krijger, Patricia H P van Hamersveld, Olaf Welting, Iris Admiraal, Shafaque Rahman, Juan J Garcia-Vallejo, Manon E Wildenberg, Laura Tomlinson, Richard Gregory, Inmaculada Rioja, Rab K Prinjha, Rebecca C Furze, Huw D Lewis, Palwinder K Mander, Sigrid E M Heinsbroek, Matthew J Bell, Wouter J de Jonge
J Crohns Colitis. 2022 Apr; 16(4): 668–681. Published online 2021 Oct 11. doi: 10.1093/ecco-jcc/jjab176
PMCID:
PMC9089418
AbstractArticlePDF–9.6M
4.
Copy number variation in the CES1 gene and the risk of non-alcoholic fatty liver in a Chinese Han population
Bing bing Chen, Jian hui Yan, Jing Zheng, He wei Peng, Xiao ling Cai, Xin ting Pan, Hui quan Li, Qi zhu Hong, Xian-E Peng
Sci Rep. 2021; 11: 13984. Published online 2021 Jul 7. doi: 10.1038/s41598-021-93549-2
Correction in:
Sci Rep. 2022; 12: 9242.
PMCID:
PMC8263572
AbstractArticlePDF–1.1M
5.
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1
Lijie Zhou, Cai Zhang, Xiong Yang, Lilong Liu, Junyi Hu, Yaxin Hou, Hong Tao, Haruhiko Sugimura, Zhaohui Chen, Liang Wang, Ke Chen
Clin Transl Med. 2021 Jun; 11(6): e449. Published online 2021 Jun 6. doi: 10.1002/ctm2.449
PMCID:
PMC8181204
AbstractArticlePDF–6.0M
6.
Carboxylesterase 1 and Precision Pharmacotherapy: Pharmacogenetics and Nongenetic Regulators
Lucy Her, Hao-Jie Zhu
Drug Metab Dispos. 2020 Mar; 48(3): 230–244. Published online 2020 Mar. doi: 10.1124/dmd.119.089680
Correction in:
Drug Metab Dispos. 2020 Nov; 48(11): 1246.
PMCID:
PMC7031766
AbstractArticlePDF–770K
7.
Catalytic Hydrolysis Mechanism of Cocaine by Human Carboxylesterase 1: An Orthoester Intermediate Slows Down the Reaction
Maocai Yan, Zhen Zhang, Zhaoming Liu, Chunyan Zhang, Jingchang Zhang, Shuai Fan, Zhaoyong Yang
Molecules. 2019 Nov; 24(22): 4057. Published online 2019 Nov 9. doi: 10.3390/molecules24224057
PMCID:
PMC6891567
AbstractArticlePDF–1.6M
8.
CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors
Xinwen Wang, Guangji Wang, Jian Shi, Jiye Aa, Rinelly Comas, Yan Liang, Hao-Jie Zhu
Pharmacogenomics J. Author manuscript; available in PMC 2019 Jan 11.
Published in final edited form as: Pharmacogenomics J. 2016 Jun; 16(3): 220–230. Published online 2015 Jun 16. doi: 10.1038/tpj.2015.42
PMCID:
PMC6329299
AbstractArticlePDF–1.8M
9.
Silencing Carboxylesterase 1 in Human THP-1 Macrophages Perturbs Genes Regulated by PPARγ/RXR and RAR/RXR: Downregulation of CYP27A1-LXRα Signaling
Lee C. Mangum, Xiang Hou, Abdolsamad Borazjani, Jung Hwa Lee, Matthew K. Ross, J. Allen Crow
Biochem J. Author manuscript; available in PMC 2019 Feb 9.
Published in final edited form as: Biochem J. 2018 Feb 9; 475(3): 621–642. Published online 2018 Feb 9. doi: 10.1042/BCJ20180008
PMCID:
PMC6159944
AbstractArticlePDF–2.6M
10.
A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms
Xinwen Wang, Nada Rida, Jian Shi, Audrey H. Wu, Barry E. Bleske, Hao-Jie Zhu
Drug Metab Dispos. 2017 Nov; 45(11): 1149–1155. Published online 2017 Nov. doi: 10.1124/dmd.117.077669
PMCID:
PMC5637814
AbstractArticlePDF–549K
11.
Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension
Mark E. Orcholski, Artyom Khurshudyan, Elya A. Shamskhou, Ke Yuan, Ian Y. Chen, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Ellen M. Hong, Ludmila Alexandrova, Tero-Pekka Alastalo, Gerald Berry, Roham T. Zamanian, Vinicio A. de Jesus Perez
Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1; 313(2): L252–L266. Published online 2017 May 4. doi: 10.1152/ajplung.00453.2016
PMCID:
PMC5582936
AbstractArticle
12.
Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients
Fei-Yan Xiao, Jian-Quan Luo, Min Liu, Bi-Lian Chen, Shan Cao, Zhao-Qian Liu, Hong-Hao Zhou, Gan Zhou, Wei Zhang
Sci Rep. 2017; 7: 7244. Published online 2017 Aug 3. doi: 10.1038/s41598-017-07736-1
PMCID:
PMC5543069
AbstractArticlePDF–1.3M
13.
Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms
Jian Shi, Xinwen Wang, Rachel F. Eyler, Yan Liang, Li Liu, Bruce A. Mueller, Hao-Jie Zhu
Basic Clin Pharmacol Toxicol. Author manuscript; available in PMC 2017 Dec 1.
Published in final edited form as: Basic Clin Pharmacol Toxicol. 2016 Dec; 119(6): 555–561. Published online 2016 Jul 21. doi: 10.1111/bcpt.12625
PMCID:
PMC5118077
AbstractArticlePDF–818K
14.
Dabigatran Etexilate Activation is Affected by the CES1 Genetic Polymorphism G143E (rs71647871) and Gender
Jian Shi, Xinwen Wang, Jenny Nguyen, Barry E. Bleske, Yan Liang, Li Liu, Hao-Jie Zhu
Biochem Pharmacol. Author manuscript; available in PMC 2017 Nov 1.
Published in final edited form as: Biochem Pharmacol. 2016 Nov 1; 119: 76–84. Published online 2016 Sep 8. doi: 10.1016/j.bcp.2016.09.003
PMCID:
PMC5061634
AbstractArticlePDF–3.4M
15.
CES1P1 variant −816A>C is not associated with hepatic carboxylesterase 1 expression, activity or antihypertensive effect of trandolapril
Hao-Jie Zhu, Taimour Y. Langaee, Yan Gong, Xinwen Wang, Carl J. Pepine, Rhonda M. Cooper-DeHoff, Julie A. Johnson, John S. Markowitz
Eur J Clin Pharmacol. Author manuscript; available in PMC 2017 Jun 1.
Published in final edited form as: Eur J Clin Pharmacol. 2016 Jun; 72(6): 681–687. Published online 2016 Feb 26. doi: 10.1007/s00228-016-2029-x
PMCID:
PMC4865408
AbstractArticlePDF–668K
16.
Comparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1
Victoria Arena de Souza, David J. Scott, Joanne E. Nettleship, Nahid Rahman, Michael H. Charlton, Martin A. Walsh, Raymond J. Owens
PLoS One. 2015; 10(12): e0143919. Published online 2015 Dec 11. doi: 10.1371/journal.pone.0143919
PMCID:
PMC4676782
AbstractArticlePDF–1.9M
17.
Polyisoprenylated Methylated Protein Methyl Esterase Is Both Sensitive to Curcumin and Overexpressed in Colorectal Cancer: Implications for Chemoprevention and Treatment
Felix Amissah, Randolph Duverna, Byron J. Aguilar, Rosemary A. Poku, Nazarius S. Lamango
Biomed Res Int. 2013; 2013: 416534. Published online 2013 Jul 1. doi: 10.1155/2013/416534
PMCID:
PMC3713324
AbstractArticlePDF–3.3M
18.
The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response
Joshua P. Lewis, Richard B. Horenstein, Kathleen Ryan, Jeffrey R. O’Connell, Quince Gibson, Braxton D. Mitchell, Keith Tanner, Sumbul Chai, Kevin P. Bliden, Udaya S. Tantry, Cody J. Peer, William D. Figg, Shawn D. Spencer, Michael A. Pacanowski, Paul A. Gurbel, Alan R. Shuldiner
Pharmacogenet Genomics. Author manuscript; available in PMC 2013 Jun 14.
Published in final edited form as: Pharmacogenet Genomics. 2013 Jan; 23(1): 1–8. doi: 10.1097/FPC.0b013e32835aa8a2
PMCID:
PMC3682407
AbstractArticlePDF–690K
19.
Carboxylesterase 1 Gene Duplication and mRNA Expression in Adipose Tissue Are Linked to Obesity and Metabolic Function
Martin Friedrichsen, Pernille Poulsen, Jørgen Wojtaszewski, Peter Riis Hansen, Allan Vaag, Henrik Berg Rasmussen
PLoS One. 2013; 8(2): e56861. Published online 2013 Feb 28. doi: 10.1371/journal.pone.0056861
PMCID:
PMC3585247
AbstractArticlePDF–222K
20.
A discriminative analytical method for detection of CES1A1 and CES1A2/CES1A3 genetic variants
Hao-Jie Zhu, Bryan Brinda, Tanya E. Froehlich, John S. Markowitz
Pharmacogenet Genomics. Author manuscript; available in PMC 2013 Mar 1.
Published in final edited form as: Pharmacogenet Genomics. 2012 Mar; 22(3): 215–218. doi: 10.1097/FPC.0b013e32834f03eb
PMCID:
PMC3412537
AbstractArticlePDF–708K

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