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Select item 106438901.

Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19

Maximilian Peter Götz, Mikkel-Ole Skjoedt, Rafael Bayarri-Olmos, Cecilie Bo Hansen, Laura Pérez-Alós, Ida Jarlhelt, Thomas Benfield, Anne Rosbjerg, Peter Garred

J Innate Immun. 2023 Jan-Dec; 15(1): 122–135. Published online 2022 Jul 11. doi: 10.1159/000525508

PMCID:: PMC10643890

Abstract Article PDF–577K

Select item 103617442.

MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence

Sonia Elhadad, David Redmond, Jenny Huang, Adrian Tan, Jeffrey Laurence

Clin Exp Immunol. 2023 Aug; 213(2): 252–264. Published online 2023 May 16. doi: 10.1093/cei/uxad055

PMCID:: PMC10361744

Abstract Article PDF–999K

Select item 95093613.

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

Rikke Zachar, Steffen Thiel, Søren Hansen, Maiken Lumby Henriksen, Mikkel-Ole Skjoedt, Karsten Skjodt, Zohra Hamzaei, Kirsten Madsen, Lars Lund, Edith Hummler, Per Svenningsen, Boye Lagerbon Jensen

Sci Rep. 2022; 12: 15955. Published online 2022 Sep 24. doi: 10.1038/s41598-022-20213-8

PMCID:: PMC9509361

Abstract Article PDF–2.0M

Select item 79853234.

Impact of MASP2 gene polymorphism and gene-tea drinking interaction on susceptibility to tuberculosis

Zihao Li, Mian Wang, Hua Zhong, Xin Huang, Xinyin Wu, Xian Zhang, Jing Wang, Jing Deng, Mengshi Chen, Lizhang Chen, Hongzhuan Tan

Sci Rep. 2021; 11: 6544. Published online 2021 Mar 22. doi: 10.1038/s41598-021-86129-x

PMCID:: PMC7985323

Abstract Article PDF–948K

Select item 75213355.

Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus

Wang‐Dong Xu, Xiao‐Yan Liu, Lin‐Chong Su, An‐Fang Huang

J Cell Mol Med. 2020 Sep; 24(18): 10432–10443. Published online 2020 Jul 17. doi: 10.1111/jcmm.15656

PMCID:: PMC7521335

Abstract Article PDF–560K

Select item 74051596.

MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti‐MASP2 antibody narsoplimab

S. Elhadad, J. Chapin, D. Copertino, K. Van Besien, J. Ahamed, J. Laurence

Clin Exp Immunol. 2021 Jan; 203(1): 96–104. Published online 2020 Aug 5. doi: 10.1111/cei.13497

PMCID:: PMC7405159

Abstract Article PDF–326K

Select item 72239727.

Should MASP-2 Deficiency Be Considered a Primary Immunodeficiency? Relevance of the Lectin Pathway

M. Isabel García-Laorden, Elisa Hernández-Brito, Carmen Muñoz-Almagro, Svetlana Pavlovic-Nesic, Iñigo Rúa-Figueroa, M. Luisa Briones, Olga Rajas, Luis Borderías, Antoni Payeras, Leonardo Lorente, Jordi Freixinet, Jose Ferreres, Ignacio Obando, Nereida González-Quevedo, Felipe Rodríguez de Castro, Jordi Solé-Violán, Carlos Rodríguez-Gallego

J Clin Immunol. 2020; 40(1): 203–210. Published online 2019 Dec 11. doi: 10.1007/s10875-019-00714-4

PMCID:: PMC7223972

Abstract Article PDF–409K

Select item 71153698.

MASP2 gene polymorphism is associated with susceptibility to hepatitis C virus infection

Siumara Tulio, Fabio R. Faucz, Renata I. Werneck, Márcia Olandoski, Rodrigo B. Alexandre, Angélica B.W. Boldt, Maria Lucia Pedroso, Iara J. de Messias-Reason

Hum Immunol. 2011 Oct; 72(10): 912–915. Published online 2011 Jul 31. doi: 10.1016/j.humimm.2011.06.016

PMCID:: PMC7115369

Abstract Article PDF–249K

Select item 70998779.

MAp19, the alternative splice product of the MASP2 gene

Søren E. Degn, Steffen Thiel, Ole Nielsen, Annette G. Hansen, Rudi Steffensen, Jens C. Jensenius

J Immunol Methods. 2011 Oct 28; 373(1): 89–101. Published online 2011 Aug 17. doi: 10.1016/j.jim.2011.08.006

PMCID:: PMC7099877

Abstract Article PDF–1.2M

Select item 523410610.

Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

E. Soemirien Kasanmoentalib, Mercedes Valls Seron, Bart Ferwerda, Michael W. Tanck, Aeilko H. Zwinderman, Frank Baas, Arie van der Ende, Matthijs C. Brouwer, Diederik van de Beek

J Neuroinflammation. 2017; 14: 2. Published online 2017 Jan 3. doi: 10.1186/s12974-016-0770-9

Correction in:: J Neuroinflammation. 2017; 14: 77.

PMCID:: PMC5234106

Abstract Article PDF–655K

Select item 395461611.

Association of MASP-2 Levels and MASP2 Gene Polymorphisms with Rheumatoid Arthritis in Patients and Their Relatives

Isabela Goeldner, Thelma Skare, Angelica B. W. Boldt, Flavia R. Nass, Iara J. Messias-Reason, Shirley R. Utiyama

PLoS One. 2014; 9(3): e90979. Published online 2014 Mar 14. doi: 10.1371/journal.pone.0090979

PMCID:: PMC3954616

Abstract Article PDF–191K

Select item 372829512.

Leprosy Association with Low MASP-2 Levels Generated by MASP2 Haplotypes and Polymorphisms Flanking MAp19 Exon 5

Angelica Beate Winter Boldt, Isabela Goeldner, Ewalda R. S. Stahlke, Steffen Thiel, Jens Christian Jensenius, Iara José Taborda de Messias-Reason

PLoS One. 2013; 8(7): e69054. Published online 2013 Jul 30. doi: 10.1371/journal.pone.0069054

PMCID:: PMC3728295

Abstract Article PDF–910K

Select item 331095713.

MASP-2 Activation is Involved in Ischemia-related Necrotic Myocardial Injury in Humans

Ming Zhang, Yunfang Hou, Erdal Cavusoglu, Daniel C. Lee, Rudi Steffensen, Liming Yang, Daniel Bashari, Jose Villamil, Motaz Moussa, George Fernaine, Jens C. Jensenius, Jonathan D. Marmur, Wilson Ko, Ketan Shevde

Int J Cardiol. Author manuscript; available in PMC 2014 Jun 20.

Published in final edited form as: Int J Cardiol. 2013 Jun 20; 166(2): 499–504. Published online 2011 Dec 15. doi: 10.1016/j.ijcard.2011.11.032

PMCID:: PMC3310957

Abstract Article PDF–631K

Select item 284249514.

Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot

Krishana C Gulla, Kshitij Gupta, Anders Krarup, Peter Gal, Wilhelm J Schwaeble, Robert B Sim, C David O’Connor, Krishnan Hajela

Immunology. 2010 Apr; 129(4): 482–495. doi: 10.1111/j.1365-2567.2009.03200.x

PMCID:: PMC2842495

Abstract Article PDF–536K

Select item 268385215.

Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection

Yan Wang, Jiangwei Yan, Yuling Shi, Ping Li, Chuanxuan Liu, Qingjun Ma, Ruifu Yang, Xiaoyi Wang, Lina zhu, Xiao Yang, Cheng Cao

BMC Infect Dis. 2009; 9: 51. Published online 2009 May 1. doi: 10.1186/1471-2334-9-51

PMCID:: PMC2683852

Abstract Article PDF–328K

Select item 1019631016.

Mannose-binding lectin gene 2 variant DD (rs 5030737) is associated with susceptibility to COVID-19 infection in the urban population of Patna City (India)

Sadhana Sharma, Bandana Kumari, Asgar Ali, Pankaj Kumar Patel, Abhay Kumar Sharma, Rathish Nair, Prabhat Kumar Singh, Krishnan Hajela

Mol Genet Genomics. 2023; 298(4): 955–963. Published online 2023 May 18. doi: 10.1007/s00438-023-02030-4

PMCID:: PMC10196310

Abstract Article PDF–839K

Select item 711267417.

MBL-associated serine proteases (MASPs) and infectious diseases

Marcia H. Beltrame, Angelica B.W. Boldt, Sandra J. Catarino, Hellen C. Mendes, Stefanie E. Boschmann, Isabela Goeldner, Iara Messias-Reason

Mol Immunol. 2015 Sep; 67(1): 85–100. Published online 2015 Apr 8. doi: 10.1016/j.molimm.2015.03.245

PMCID:: PMC7112674

Abstract Article PDF–1.1M

Select item 689686018.

Mannose-Binding Lectin and Mannose-Binding Lectin-Associated Serine Protease-2 Genotypes and Serum Levels in Patients with Sporotrichosis

Fangfang Bao, Xi’an Fu, Gongqi Yu, Zhenzhen Wang, Hong Liu, Furen Zhang

Am J Trop Med Hyg. 2019 Dec; 101(6): 1322–1324. Published online 2019 Sep 23. doi: 10.4269/ajtmh.19-0470

PMCID:: PMC6896860

Abstract Article PDF–212K

Select item 652715419.

Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors

Dávid Szakács, Andrea Kocsis, Róbert Szász, Péter Gál, Gábor Pál

J Biol Chem. 2019 May 17; 294(20): 8227–8237. Published online 2019 Apr 5. doi: 10.1074/jbc.RA119.008315

PMCID:: PMC6527154

Abstract Article PDF–1.3M

Select item 648810020.

Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease

Thaisa Lucas Sandri, Fabiana Antunes Andrade, Kárita Cláudia Freitas Lidani, Elias Einig, Angelica Beate Winter Boldt, Benjamin Mordmüller, Meral Esen, Iara J. Messias-Reason

PLoS Negl Trop Dis. 2019 Apr; 13(4): e0007324. Published online 2019 Apr 17. doi: 10.1371/journal.pntd.0007324