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Select item 110638391.

Profiling the activity of the para-caspase MALT1 in B-cell acute lymphoblastic leukemia for potential targeted therapeutic application

Firas M. Safa, Terri Rasmussen, Lorena Fontan, Min Xia, Ari Melnick, Adrian Wiestner, Patricia Lobelle-Rich, Jan A. Burger, Yara Mouawad, Hana Safah, Erik K Flemington, Nakhle S. Saba

Haematologica. 2024 May 1; 109(5): 1348–1358. Published online 2023 Sep 28. doi: 10.3324/haematol.2023.283178

PMCID:: PMC11063839

Abstract Article PDF–4.6M

Select item 109023462.

Long-term monitoring of gastric mucosa-associated lymphoid tissue lymphoma in patients with extra copies of the MALT1 gene

Masaya Iwamuro, Ryuta Takenaka, Koji Miyahara, Shotaro Okanoue, Masao Yoshioka, Chihiro Sakaguchi, Kumiko Yamamoto, Yoshinari Kawai, Tatsuya Toyokawa, Takehiro Tanaka, Motoyuki Otsuka

Sci Rep. 2024; 14: 4953. Published online 2024 Feb 29. doi: 10.1038/s41598-024-55663-9

PMCID:: PMC10902346

Abstract Article PDF–1012K

Select item 107338373.

Oncogene-induced MALT1 protease activity drives posttranscriptional gene expression in malignant lymphomas

Nicole Wimberger, Franziska Ober, Göksu Avar, Michael Grau, Wendan Xu, Georg Lenz, Michael P. Menden, Daniel Krappmann

Blood. 2023 Dec 7; 142(23): 1985–2001. Published online 2023 Aug 28. doi: 10.1182/blood.2023021299

PMCID:: PMC10733837

Abstract Article

Select item 95101104.

Assignment of IVL-Methyl side chain of the ligand-free monomeric human MALT1 paracaspase-IgL₃ domain in solution

Xiao Han, Maria Levkovets, Dmitry Lesovoy, Renhua Sun, Johan Wallerstein, Tatyana Sandalova, Tatiana Agback, Adnane Achour, Peter Agback, Vladislav Yu. Orekhov

Biomol NMR Assign. 2022; 16(2): 363–371. Published online 2022 Sep 12. doi: 10.1007/s12104-022-10105-3

PMCID:: PMC9510110

Abstract Article PDF–1.8M

Select item 93676915.

MALT1 regulates Th2 and Th17 differentiation via NF-κB and JNK pathways, as well as correlates with disease activity and treatment outcome in rheumatoid arthritis

Qiubo Wang, Yapeng Wang, Qingyang Liu, Ying Chu, Rui Mi, Fengying Jiang, Jingjing Zhao, Kelong Hu, Ran Luo, Yufeng Feng, Harrison Lee, Dong Zhou, Jingyi Mi, Ruoyu Deng

Front Immunol. 2022; 13: 913830. Published online 2022 Jul 28. doi: 10.3389/fimmu.2022.913830

PMCID:: PMC9367691

Abstract Article PDF–6.3M

Select item 92799676.

MALT1 positively relates to Th17 cells, inflammation/activity degree, and its decrement along with treatment reflects TNF inhibitor response in ankylosing spondylitis patients

Jie Yuan, Lei Xiang, Feng Wang, Lin Zhang, Gaozhan Liu, Xiuli Chang, Anbing Zhang, Ying Tao

J Clin Lab Anal. 2022 Jul; 36(7): e24472. Published online 2022 May 27. doi: 10.1002/jcla.24472

PMCID:: PMC9279967

Abstract Article PDF–3.3M

Select item 91691667.

Mucosa‐associated lymphoid tissue lymphoma translocation protein 1 in rheumatoid arthritis: Longitudinal change after treatment and correlation with treatment efficacy of tumor necrosis factor inhibitors

Feng Wang, Gaozhan Liu, Lei Xiang, Jie Yuan, Ying Tao, Lin Zhang, Anbing Zhang, Xiuli Chang

J Clin Lab Anal. 2022 Jun; 36(6): e24449. Published online 2022 May 2. doi: 10.1002/jcla.24449

PMCID:: PMC9169166

Abstract Article PDF–3.9M

Select item 91025278.

MALT1 in asthma children: A potential biomarker for monitoring exacerbation risk and Th1/Th2 imbalance‐mediated inflammation

Liying Liu, Yang Gao, Yonghua Si, Baohuan Liu, Xingyue Liu, Guanhui Li, Rong Wang

J Clin Lab Anal. 2022 May; 36(5): e24379. Published online 2022 Mar 30. doi: 10.1002/jcla.24379

PMCID:: PMC9102527

Abstract Article PDF–4.0M

Select item 89936589.

Aberrant blood MALT1 and its relevance with multiple organic dysfunctions, T helper cells, inflammation, and mortality risk of sepsis patients

Yibin Wang, Qinghe Huang, Fuyun He

J Clin Lab Anal. 2022 Apr; 36(4): e24331. Published online 2022 Mar 9. doi: 10.1002/jcla.24331

PMCID:: PMC8993658

Abstract Article PDF–768K

Select item 889827110.

MALT1 is a Targetable Driver of Epithelial-to-Mesenchymal Transition in Claudin-low, Triple-Negative Breast Cancer

Jia-Ying (Lloyd) Lee, Prasanna Ekambaram, Neil M. Carleton, Dong Hu, Linda R. Klei, Zongyou Cai, Max I. Myers, Nathaniel E. Hubel, Lidija Covic, Sameer Agnihotri, Daniel Krappmann, Frédéric Bornancin, Adrian V. Lee, Steffi Oesterreich, Linda M. McAllister-Lucas, Peter C. Lucas

Mol Cancer Res. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Mol Cancer Res. 2022 Mar 1; 20(3): 373–386. doi: 10.1158/1541-7786.MCR-21-0208

PMCID:: PMC8898271

Abstract Article PDF–3.2M

Select item 876143611.

Blood MALT1, Th1, and Th17 cells are dysregulated, inter‐correlated, and correlated with disease activity in rheumatoid arthritis patients; meanwhile, MALT1 decline during therapy relates to treatment outcome

Zhuang Ye, Lu Chen, Ying Fang, Ling Zhao

J Clin Lab Anal. 2022 Jan; 36(1): e24112. Published online 2021 Nov 17. doi: 10.1002/jcla.24112

PMCID:: PMC8761436

Abstract Article PDF–736K

Select item 856170012.

Progressive B cell depletion in human MALT1 deficiency

Motoshi Sonoda, Masataka Ishimura, Katsuhide Eguchi, Yutaro Yada, Nina Lenhartová, Akira Shiraishi, Tamami Tanaka, Yasunari Sakai, Shouichi Ohga

Clin Exp Immunol. 2021 Dec; 206(3): 237–247. Published online 2021 Oct 7. doi: 10.1111/cei.13662

PMCID:: PMC8561700

Abstract Article PDF–1.5M

Select item 855204113.

MALT1-Dependent Cleavage of HOIL1 Modulates Canonical NF-κB Signaling and Inflammatory Responsiveness

Shan-Yu Fung, Henry Y. Lu, Mehul Sharma, Ashish A. Sharma, Aabida Saferali, Alicia Jia, Libin Abraham, Theo Klein, Michael R. Gold, Luigi D. Noterangelo, Christopher M. Overall, Stuart E. Turvey

Front Immunol. 2021; 12: 749794. Published online 2021 Oct 14. doi: 10.3389/fimmu.2021.749794

PMCID:: PMC8552041

Abstract Article PDF–8.8M

Select item 841846314.

MALT1 positively correlates with Th1 cells, Th17 cells, and their secreted cytokines and also relates to disease risk, severity, and prognosis of acute ischemic stroke

Xia Chen, Xuemei Zhang, Ling Lan, Guoyao Xu, Yanchun Li, Shaoming Huang

J Clin Lab Anal. 2021 Sep; 35(9): e23903. Published online 2021 Jul 17. doi: 10.1002/jcla.23903

PMCID:: PMC8418463

Abstract Article PDF–1.0M

Select item 788582615.

Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL

Lorena Fontan, Rebecca Goldstein, Gabriella Casalena, Matthew Durant, Matthew R. Teater, Jimmy Wilson, Jude Phillip, Min Xia, Shivem Shah, Ilkay Us, Himaly Shinglot, Ankur Singh, Giorgio Inghirami, Ari Melnick

Blood. 2021 Feb 11; 137(6): 788–800. Prepublished online 2020 Aug 12. doi: 10.1182/blood.2019004713

PMCID:: PMC7885826

Abstract Article

Select item 744554916.

Human immune disorder associated with homozygous hypomorphic mutation affecting MALT1B splice variant

Necil Kutukculer, Thomas Seeholzer, Thomas J. O’Neill, Carina Graß, Ayca Aykut, Neslihan Edeer Karaca, Asude Durmaz, Ozgur Cogulu, Guzide Aksu, Torben Gehring, Andreas Gewies, Daniel Krappmann

J Allergy Clin Immunol. 2021 Feb; 147(2): 775–778.e8. Published online 2020 Aug 25. doi: 10.1016/j.jaci.2020.07.034

PMCID:: PMC7445549

Article PDF–1.2M

Select item 655640617.

The MALT1 locus and Peanut Avoidance in the Risk for Peanut Allergy

Alexandra Winters, Henry T Bahnson, Ingo Ruczinski, Meher P Boorgula, Claire Malley, Ali R Keramati, Sameer Chavan, David Larson, Karen Cerosaletti, Peter H Sayre, Marshall Plaut, George Du Toit, Gideon Lack, Kathleen C Barnes, Gerald T Nepom, Rasika A Mathias, Immune Tolerance Network LEAP Study Team

J Allergy Clin Immunol. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: J Allergy Clin Immunol. 2019 Jun; 143(6): 2326–2329. Published online 2019 Feb 27. doi: 10.1016/j.jaci.2019.02.016

PMCID:: PMC6556406

Abstract Article PDF–621K

Select item 615998318.

Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth

Lorena Fontán, Qi Qiao, John M. Hatcher, Gabriella Casalena, Ilkay Us, Matt Teater, Matt Durant, Guangyan Du, Min Xia, Natalia Bilchuk, Spandan Chennamadhavuni, Giuseppe Palladino, Giorgio Inghirami, Ulrike Philippar, Hao Wu, David A. Scott, Nathanael S. Gray, Ari Melnick

J Clin Invest. 2018 Oct 1; 128(10): 4397–4412. Published online 2018 Jul 19. doi: 10.1172/JCI99436

PMCID:: PMC6159983

Abstract Article PDF–6.8M

Select item 612532819.

Holding All the CARDs: How MALT1 Controls CARMA/CARD-Dependent Signaling

Mélanie Juilland, Margot Thome

Front Immunol. 2018; 9: 1927. Published online 2018 Aug 30. doi: 10.3389/fimmu.2018.01927

PMCID:: PMC6125328

Abstract Article PDF–2.4M

Select item 589151520.

Achromobacter Infection Is Rare in Japanese Patients with Pulmonary B-cell Lymphoma

Satsuki Aoyama, Ayako Masaki, Yuma Sakamoto, Hisashi Takino, Takayuki Murase, Koichi Ohshima, Tadashi Yoshino, Seiichi Kato, Hiroshi Inagaki

Intern Med. 2018 Mar 15; 57(6): 789–794. Published online 2017 Nov 20. doi: 10.2169/internalmedicine.9430-17

PMCID:: PMC5891515

Abstract Article PDF–290K

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PMC Links for Gene (Select 10892) (151)
PMC
PREDICTED: Homo sapiens MALT1 paracaspase (MALT1), transcript variant X1, misc_R...
PREDICTED: Homo sapiens MALT1 paracaspase (MALT1), transcript variant X1, misc_RNA
gi|2217316083|ref|XR_007066087.1|

Nucleotide
RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1...
RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1; AltName: Full=MALT lymphoma-associated translocation; AltName: Full=Paracaspase
gi|20455075|sp|Q9UDY8.1|MALT1_HUMAN

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