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Select item 44402561.

A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway

Lihua Sun, Chao Xu, Guoqing Chen, Min Yu, Songwei Yang, Yuan Qiu, Ke Peng, Wensheng Wang, Weidong Xiao, Hua Yang

Int J Biol Sci. 2015; 11(6): 664–671. Published online 2015 Apr 27. doi: 10.7150/ijbs.10783

PMCID:: PMC4440256

Abstract Article PDF–1.2M

Select item 59355222.

Redundant and antagonistic roles of XTP3B and OS9 in decoding glycan and non-glycan degrons in ER-associated degradation

Annemieke T. van der Goot, Margaret M. P. Pearce, Dara E. Leto, Thomas A. Shaler, Ron R. Kopito

Mol Cell. Author manuscript; available in PMC 2019 May 3.

Published in final edited form as: Mol Cell. 2018 May 3; 70(3): 516–530.e6. Published online 2018 Apr 26. doi: 10.1016/j.molcel.2018.03.026

PMCID:: PMC5935522

Abstract Article PDF–1.9M

Select item 42600353.

A novel long non-coding RNA ENST00000480739 suppresses tumour cell invasion by regulating OS-9 and HIF-1α in pancreatic ductal adenocarcinoma

Y-W Sun, Y-F Chen, J Li, Y-M Huo, D-J Liu, R Hua, J-F Zhang, W Liu, J-Y Yang, X-L Fu, T Yan, J Hong, H Cao

Br J Cancer. 2014 Nov 25; 111(11): 2131–2141. Published online 2014 Oct 14. doi: 10.1038/bjc.2014.520

PMCID:: PMC4260035

Abstract Article PDF–1.7M

Select item 447594.

Direct isolation of genes encoded within a homogeneously staining region by chromosome microdissection.

Y A Su, J M Trent, X Y Guan, P S Meltzer

Proc Natl Acad Sci U S A. 1994 Sep 13; 91(19): 9121–9125. doi: 10.1073/pnas.91.19.9121

PMCID:: PMC44759

Summary Page Browse PDF–1.3M

Select item 61096145.

Abnormal Expression of ER Quality Control and ER Associated Degradation Proteins in the Dorsolateral Prefrontal Cortex in Schizophrenia

Pitna Kim, Madeline R. Scott, James H. Meador-Woodruff

Schizophr Res. Author manuscript; available in PMC 2019 Jul 30.

Published in final edited form as: Schizophr Res. 2018 Jul; 197: 484–491. Published online 2018 Feb 26. doi: 10.1016/j.schres.2018.02.010

PMCID:: PMC6109614

Abstract Article PDF–743K

Select item 27193446.

Human OS-9, a Lectin Required for Glycoprotein Endoplasmic Reticulum-associated Degradation, Recognizes Mannose-trimmed N-Glycans

Nobuko Hosokawa, Yukiko Kamiya, Daiki Kamiya, Koichi Kato, Kazuhiro Nagata

J Biol Chem. 2009 Jun 19; 284(25): 17061–17068. Published online 2009 Apr 3. doi: 10.1074/jbc.M809725200

PMCID:: PMC2719344

Abstract Article PDF–602K

Select item 48134767.

OS9 Protein Interacts with Na-K-2Cl Co-transporter (NKCC2) and Targets Its Immature Form for the Endoplasmic Reticulum-associated Degradation Pathway

Elie Seaayfan, Nadia Defontaine, Sylvie Demaretz, Nancy Zaarour, Kamel Laghmani

J Biol Chem. 2016 Feb 26; 291(9): 4487–4502. Published online 2015 Dec 31. doi: 10.1074/jbc.M115.702514

PMCID:: PMC4813476

Abstract Article PDF–2.3M

Select item 32040578.

Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1

Efrat Ron, Marina Shenkman, Bella Groisman, Yana Izenshtein, Julia Leitman, Gerardo Z. Lederkremer

Mol Biol Cell. 2011 Nov 1; 22(21): 3945–3954. doi: 10.1091/mbc.E10-12-0944

PMCID:: PMC3204057

Abstract Article PDF–2.1M

Select item 41162979.

OS-9 facilitates turnover of nonnative GRP94 marked by hyperglycosylation

Devin Dersh, Stephanie M. Jones, Davide Eletto, John C. Christianson, Yair Argon

Mol Biol Cell. 2014 Aug 1; 25(15): 2220–2234. doi: 10.1091/mbc.E14-03-0805

PMCID:: PMC4116297

Abstract Article PDF–4.3M

Select item 376255910.

A Dual Task for the Xbp1-responsive OS-9 Variants in the Mammalian Endoplasmic Reticulum: Inhibiting Secretion of Misfolded Protein Conformers and Enhancing their Disposal

Riccardo Bernasconi, Thomas Pertel, Jeremy Luban, Maurizio Molinari

J Biol Chem. 2008 Jun 13; 283(24): 16446–16454. Published online 2008 Apr 15. doi: 10.1074/jbc.M802272200

PMCID:: PMC3762559

Abstract Article PDF–491K

Select item 308476111.

The Function of Hypoxia-Inducible Factor (HIF) Is Independent of the Endoplasmic Reticulum Protein OS-9

Ulf Brockmeier, Corinna Platzek, Kirsten Schneider, Pauline Patak, André Bernardini, Joachim Fandrey, Eric Metzen

PLoS One. 2011; 6(4): e19151. Published online 2011 Apr 29. doi: 10.1371/journal.pone.0019151

PMCID:: PMC3084761

Abstract Article PDF–750K

Select item 566544012.

Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD)

Jasmin Schulz, Dönem Avci, Markus A. Queisser, Aljona Gutschmidt, Lena-Sophie Dreher, Emma J. Fenech, Norbert Volkmar, Yuki Hayashi, Thorsten Hoppe, John C. Christianson

J Cell Sci. 2017 Oct 1; 130(19): 3322–3335. doi: 10.1242/jcs.206847

PMCID:: PMC5665440

Abstract Article

Select item 273641313.

A luminal flavoprotein in endoplasmic reticulum-associated degradation

Jan Riemer, Christian Appenzeller-Herzog, Linda Johansson, Bernd Bodenmiller, Rasmus Hartmann-Petersen, Lars Ellgaard

Proc Natl Acad Sci U S A. 2009 Sep 1; 106(35): 14831–14836. Published online 2009 Aug 19. doi: 10.1073/pnas.0900742106

PMCID:: PMC2736413

Abstract Article PDF–1.2M

Select item 404959114.

EDEM2 and OS-9 Are Required for ER-Associated Degradation of Non-Glycosylated Sonic Hedgehog

Hsiang-Yun Tang, Chih-Hsiang Huang, Ya-Han Zhuang, John C. Christianson, Xin Chen

PLoS One. 2014; 9(6): e92164. Published online 2014 Jun 9. doi: 10.1371/journal.pone.0092164

PMCID:: PMC4049591

Abstract Article PDF–5.9M

Select item 308953615.

SEL1L Protein Critically Determines the Stability of the HRD1-SEL1L Endoplasmic Reticulum-associated Degradation (ERAD) Complex to Optimize the Degradation Kinetics of ERAD Substrates

Yasutaka Iida, Tsutomu Fujimori, Katsuya Okawa, Kazuhiro Nagata, Ikuo Wada, Nobuko Hosokawa

J Biol Chem. 2011 May 13; 286(19): 16929–16939. Published online 2011 Mar 24. doi: 10.1074/jbc.M110.215871

PMCID:: PMC3089536

Abstract Article PDF–2.6M

Select item 500007316.

Lunapark Is a Component of a Ubiquitin Ligase Complex Localized to the Endoplasmic Reticulum Three-way Junctions

Yupeng Zhao, Ting Zhang, Huanhuan Huo, Yihong Ye, Yanfen Liu

J Biol Chem. 2016 Aug 26; 291(35): 18252–18262. Published online 2016 Jul 7. doi: 10.1074/jbc.M116.737783

PMCID:: PMC5000073

Abstract Article PDF–3.2M

Select item 485029217.

Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABA_A) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation

Xiao-Jing Di, Ya-Juan Wang, Dong-Yun Han, Yan-Lin Fu, Adam S. Duerfeldt, Brian S. J. Blagg, Ting-Wei Mu

J Biol Chem. 2016 Apr 29; 291(18): 9526–9539. Published online 2016 Mar 4. doi: 10.1074/jbc.M115.705004

PMCID:: PMC4850292

Abstract Article PDF–3.1M

Select item 467024018.

IRE1a is an endogenous substrate of endoplasmic reticulum-associated degradation

Shengyi Sun, Guojun Shi, Haibo Sha, Yewei Ji, Xuemei Han, Xin Shu, Hongming Ma, Takamasa Inoue, Beixue Gao, Hana Kim, Pengcheng Bu, Robert D. Guber, Xiling Shen, Ann-Hwee Lee, Takao Iwawaki, Adrienne W. Paton, James C. Paton, Deyu Fang, Billy Tsai, John R. Yates, III, Haoquan Wu, Sander Kersten, Qiaoming Long, Gerald E. Duhamel, Kenneth W. Simpson, Ling Qi

Nat Cell Biol. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Nat Cell Biol. 2015 Dec; 17(12): 1546–1555. Published online 2015 Nov 9. doi: 10.1038/ncb3266

PMCID:: PMC4670240

Abstract Article PDF–2.5M

Select item 325895019.

Human XTP3-B Forms an Endoplasmic Reticulum Quality Control Scaffold with the HRD1-SEL1L Ubiquitin Ligase Complex and BiP

Nobuko Hosokawa, Ikuo Wada, Koji Nagasawa, Tatsuya Moriyama, Katsuya Okawa, Kazuhiro Nagata

J Biol Chem. 2008 Jul 25; 283(30): 20914–20924. doi: 10.1074/jbc.M709336200

PMCID:: PMC3258950

Abstract Article PDF–884K

Select item 252791020.

SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins

Britta Mueller, Elizabeth J. Klemm, Eric Spooner, Jasper H. Claessen, Hidde L. Ploegh

Proc Natl Acad Sci U S A. 2008 Aug 26; 105(34): 12325–12330. Published online 2008 Aug 18. doi: 10.1073/pnas.0805371105

PMCID:: PMC2527910

Abstract Article PDF–933K

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PMC Links for Gene (Select 10956) (72)
PMC
Homo sapiens OS9 endoplasmic reticulum lectin (OS9), transcript variant 4, mRNA
Homo sapiens OS9 endoplasmic reticulum lectin (OS9), transcript variant 4, mRNA
gi|1890266940|ref|NM_001017958.3|

Nucleotide
protein OS-9 isoform 4 precursor [Homo sapiens]
protein OS-9 isoform 4 precursor [Homo sapiens]
gi|63252870|ref|NP_001017958.1|

Protein
protein OS-9 isoform 11 precursor [Homo sapiens]
protein OS-9 isoform 11 precursor [Homo sapiens]
gi|2287780839|ref|NP_001397909.1|

Protein
RecName: Full=Protein OS-9; AltName: Full=Amplified in osteosarcoma 9; Flags: Pr...
RecName: Full=Protein OS-9; AltName: Full=Amplified in osteosarcoma 9; Flags: Precursor
gi|3024310|sp|Q13438.1|OS9_HUMAN

Protein

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