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Select item 107786011.

MLLT11 Regulates Endometrial Stroma Cell Adhesion, Proliferation and Survival in Ectopic Lesions of Women with Advanced Endometriosis

Katharina Proestling, Heinrich Husslein, Quanah James Hudson, Matthias Witzmann-Stern, Barbara Widmar, Zsuzsanna Bagó-Horváth, Lejla Sandrieser, Alexandra Perricos, René Wenzl, Iveta Yotova

Int J Mol Sci. 2024 Jan; 25(1): 439. Published online 2023 Dec 28. doi: 10.3390/ijms25010439

PMCID:: PMC10778601

Abstract Article PDF–2.6M

Select item 107089522.

MLLT11 siRNA Inhibits the Migration and Promotes the Apoptosis of MDA-MB-231 Breast Cancer Cells

Xiangrong Liu, Wenqi Bai, Jianrong Li, Jinfeng Ma, Yan Liu, Zhixiang Wang, Linjie Hu, Zheng Li, Dimitri Papukashvili, Nino Rcheulishvili, Fusheng Wang, Xiaoqing Lu

Breast J. 2023; 2023: 6282654. Published online 2023 Dec 1. doi: 10.1155/2023/6282654

PMCID:: PMC10708952

Abstract Article PDF–2.1M

Select item 72422613.

AF1q Expression Associates with CD44 and STAT3 and Impairs Overall Survival in Adenoid Cystic Carcinoma of the Head and Neck

Lorenz C. Kadletz, Faris F. Brkic, Bernhard J. Jank, Sven Schneider, Julia Cede, Rudolf Seemann, Elisabeth S. Gruber, Elisabeth Gurnhofer, Gregor Heiduschka, Lukas Kenner

Pathol Oncol Res. 2020; 26(2): 1287–1292. Published online 2019 Jul 4. doi: 10.1007/s12253-019-00696-z

PMCID:: PMC7242261

Abstract Article PDF–1.0M

Select item 69128244.

The Oncogene AF1Q is Associated with WNT and STAT Signaling and Offers a Novel Independent Prognostic Marker in Patients with Resectable Esophageal Cancer

Elisabeth S. Gruber, Georg Oberhuber, Peter Birner, Michaela Schlederer, Michael Kenn, Wolfgang Schreiner, Gerd Jomrich, Sebastian F. Schoppmann, Michael Gnant, William Tse, Lukas Kenner

Cells. 2019 Nov; 8(11): 1357. Published online 2019 Oct 30. doi: 10.3390/cells8111357

Correction in:: Cells. 2020 Dec; 9(12): 2724.

PMCID:: PMC6912824

Abstract Article PDF–2.0M

Select item 61132875.

Novel AF1q/MLLT11 favorably affects imatinib resistance and cell survival in chronic myeloid leukemia

Wei Li, Min Ji, Fei Lu, Yihua Pang, Xin Dong, Jingru Zhang, Peng Li, Jingjing Ye, Shaolei Zang, Daoxin Ma, Chunyan Ji

Cell Death Dis. 2018 Sep; 9(9): 855. Published online 2018 Aug 28. doi: 10.1038/s41419-018-0900-7

PMCID:: PMC6113287

Abstract Article PDF–1.2M

Select item 54549006.

AF1q Mediates Tumor Progression in Colorectal Cancer by Regulating AKT Signaling

Jingwei Hu, Guodong Li, Liang Liu, Yatao Wang, Xiaolan Li, Jianping Gong

Int J Mol Sci. 2017 May; 18(5): 987. Published online 2017 May 5. doi: 10.3390/ijms18050987

PMCID:: PMC5454900

Abstract Article PDF–6.2M

Select item 54103017.

Involvement of AF1q/MLLT11 in the progression of ovarian cancer

Paola Tiberio, Ludmila Lozneanu, Valentina Angeloni, Elena Cavadini, Patrizia Pinciroli, Maurizio Callari, Maria Luisa Carcangiu, Domenica Lorusso, Francesco Raspagliesi, Valentina Pala, Maria Grazia Daidone, Valentina Appierto

Oncotarget. 2017 Apr 4; 8(14): 23246–23264. Published online 2017 Feb 21. doi: 10.18632/oncotarget.15574

PMCID:: PMC5410301

Abstract Article PDF–4.4M

Select item 33837058.

AF1q: A Novel Mediator of Basal and 4-HPR-Induced Apoptosis in Ovarian Cancer Cells

Paola Tiberio, Elena Cavadini, Maurizio Callari, Maria Grazia Daidone, Valentina Appierto

PLoS One. 2012; 7(6): e39968. Published online 2012 Jun 26. doi: 10.1371/journal.pone.0039968

PMCID:: PMC3383705

Abstract Article PDF–849K

Select item 31587139.

AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway

Aude Parcelier, Nesrine Maharzi, Marc Delord, Macarena Robledo-Sarmiento, Elisabeth Nelson, Halima Belakhdar-Mekid, Marika Pla, Klaudia Kuranda, Veronique Parietti, Michele Goodhardt, Nicolas Legrand, Irwin D. Bernstein, Jean Claude Gluckman, François Sigaux, Bruno Canque

Blood. 2011 Aug 18; 118(7): 1784–1796. Prepublished online 2011 Jun 28. doi: 10.1182/blood-2011-01-333179

PMCID:: PMC3158713

Abstract Article

Select item 890375810.

MLLT11-TRIL complex promotes the progression of endometrial cancer through PI3K/AKT/mTOR signaling pathway

Jingnan Liao, Huan Chen, Mingming Qi, Jinjin Wang, Mingyuan Wang

Cancer Biol Ther. 2022; 23(1): 211–224. Published online 2022 Mar 6. doi: 10.1080/15384047.2022.2046450

PMCID:: PMC8903758

Abstract Article PDF–4.0M

Select item 861816711.

A Monoallelic Variant in REST Is Associated with Non-Syndromic Autosomal Dominant Hearing Impairment in a South African Family

Noluthando Manyisa, Isabelle Schrauwen, Leonardo Alves de Souza Rios, Shaheen Mowla, Cedrik Tekendo-Ngongang, Kalinka Popel, Kevin Esoh, Thashi Bharadwaj, Liz M. Nouel-Saied, Anushree Acharya, Abdul Nasir, Edmond Wonkam-Tingang, Carmen de Kock, Collet Dandara, Suzanne M. Leal, Ambroise Wonkam

Genes (Basel) 2021 Nov; 12(11): 1765. Published online 2021 Nov 6. doi: 10.3390/genes12111765

PMCID:: PMC8618167

Abstract Article PDF–8.4M

Select item 456086112.

RE1 silencing transcription factor (REST) negatively regulates ALL1-fused from chromosome 1q (AF1q) gene transcription

Yuanyuan Hu, Qianwen Sun, Chen Zhang, Qingquan Sha, Xiulian Sun

BMC Mol Biol. 2015; 16: 15. Published online 2015 Sep 5. doi: 10.1186/s12867-015-0043-7

PMCID:: PMC4560861

Abstract Article PDF–1.3M

Select item 465303613.

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

Jino Park, Michaela Schlederer, Martin Schreiber, Ryan Ice, Olaf Merkel, Martin Bilban, Sebastian Hofbauer, Soojin Kim, Joseph Addison, Jie Zou, Chunyan Ji, Silvia T. Bunting, Zhengqi Wang, Menachem Shoham, Gang Huang, Zsuzsanna Bago-Horvath, Laura F. Gibson, Yon Rojanasakul, Scot Remick, Alexey Ivanov, Elena Pugacheva, Kevin D. Bunting, Richard Moriggl, Lukas Kenner, William Tse

Oncotarget. 2015 Aug 21; 6(24): 20697–20710. Published online 2015 Jun 7. doi: 10.18632/oncotarget.4136

PMCID:: PMC4653036

Abstract Article PDF–6.2M

Select item 519007114.

MLLT11/AF1q boosts oncogenic STAT3 activity through Src-PDGFR tyrosine kinase signaling

Jino Park, Soojin Kim, Joongho Joh, Scot C. Remick, Donald M. Miller, Jun Yan, Zeyad Kanaan, Ju-Hsien Chao, Maxwell M. Krem, Soumit K. Basu, Shotaro Hagiwara, Lukas Kenner, Richard Moriggl, Kevin D. Bunting, William Tse

Oncotarget. 2016 Jul 12; 7(28): 43960–43973. Published online 2016 Jun 1. doi: 10.18632/oncotarget.9759

PMCID:: PMC5190071

Abstract Article PDF–6.8M

Select item 614100915.

The Shieldin complex mediates 53BP1-dependent DNA repair

Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J. Pettitt, Alexanda K. Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann, Stefano Annunziato, Dragomir B. Krastev, Feifei Song, Inger Brandsma, Jessica Frankum, Rachel Brough, Alana Sherker, Sébastien Landry, Rachel K. Szilard, Meagan M. Munro, Andrea McEwan, Théo Goullet de Rugy, Zhen-Yuan Lin, Traver Hart, Jason Moffat, Anne-Claude Gingras, Alberto Martin, Haico van Attikum, Jos Jonkers, Christopher J. Lord, Sven Rottenberg, Daniel Durocher

Nature. Author manuscript; available in PMC 2019 Jan 18.

Published in final edited form as: Nature. 2018 Aug; 560(7716): 117–121. Published online 2018 Jul 18. doi: 10.1038/s41586-018-0340-7

PMCID:: PMC6141009

Abstract Article PDF–5.1M

Select item 613844116.

CRL4^AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling

Si‐Han Chen, Gwendolyn M Jang, Ruth Hüttenhain, David E Gordon, Dan Du, Billy W Newton, Jeffrey R Johnson, Joseph Hiatt, Judd F Hultquist, Tasha L Johnson, Yi‐Liang Liu, Lily A Burton, Jordan Ye, Kurt M Reichermeier, Robert M Stroud, Alexander Marson, Jayanta Debnath, John D Gross, Nevan J Krogan

EMBO J. 2018 Sep 14; 37(18): e97508. Published online 2018 Aug 30. doi: 10.15252/embj.201797508

PMCID:: PMC6138441

Abstract Article PDF–1.7M

Select item 857430717.

Interactome profiling reveals interaction of SARS-CoV-2 NSP13 with host factor STAT1 to suppress interferon signaling

Kuan Feng, Yuan-Qin Min, Xiulian Sun, Fei Deng, Peiqing Li, Hualin Wang, Yun-Jia Ning

J Mol Cell Biol. 2021 Oct; 13(10): 760–762. Published online 2021 Oct 23. doi: 10.1093/jmcb/mjab068

PMCID:: PMC8574307

Article PDF–764K

Select item 711512818.

Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan

Chen Khuan Wong, Arthur William Lambert, Sait Ozturk, Panagiotis Papageorgis, Delia Lopez, Ning Shen, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Hui Feng, Sam Thiagalingam

Mol Cancer Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 414–423. Published online 2020 Jan 13. doi: 10.1158/1541-7786.MCR-19-0525

PMCID:: PMC7115128

Abstract Article PDF–1.6M

Select item 738231319.

MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation

Gayoung Seo, Han Han, Rebecca Elizabeth Vargas, Bing Yang, Xu Li, Wenqi Wang

Cell Rep. Author manuscript; available in PMC 2020 Jul 25.

Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107860. doi: 10.1016/j.celrep.2020.107860

PMCID:: PMC7382313

Abstract Article PDF–2.6M

Select item 936044320.

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner

Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas

Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3

PMCID:: PMC9360443

Abstract Article PDF–5.8M

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