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Select item 110941981.

Bax Inhibitor-1 preserves pancreatic β-cell proteostasis by limiting proinsulin misfolding and programmed cell death

Marina Blanc, Lama Habbouche, Peng Xiao, Cynthia Lebeaupin, Marion Janona, Nathalie Vaillant, Marie Irondelle, Jérôme Gilleron, Florent Murcy, Déborah Rousseau, Carmelo Luci, Thibault Barouillet, Sandrine Marchetti, Sandra Lacas-Gervais, Laurent Yvan-Charvet, Philippe Gual, Alessandra K. Cardozo, Béatrice Bailly-Maitre

Cell Death Dis. 2024 May; 15(5): 334. Published online 2024 May 14. doi: 10.1038/s41419-024-06701-x

PMCID:: PMC11094198

Abstract Article PDF–4.9M

Select item 103365802.

TMBIM6 deficiency leads to bone loss by accelerating osteoclastogenesis

Sun-Ju Yi, You-Jee Jang, Seokchan Lee, Sung-Jin Cho, Kyuho Kang, Jae-Il Park, Han-Jung Chae, Hyung-Ryong Kim, Kyunghwan Kim

Redox Biol. 2023 Aug; 64: 102804. Published online 2023 Jun 28. doi: 10.1016/j.redox.2023.102804

Correction in:: Redox Biol. 2023 Oct; 66: 102844.

PMCID:: PMC10336580

Abstract Article PDF–9.5M

Select item 72978313.

Bax inhibitor-1 deficiency leads to obesity by increasing Ca²⁺-dependent insulin secretion

Koenraad Philippaert, Michael Roden, Dmitrij Lisak, Diones Bueno, Tomas Jelenik, Konstantin Radyushkin, Teresa Schacht, Margot Mesuere, Verena Wüllner, Ann-Kathrin Herrmann, Jan Baumgart, Rudi Vennekens, Axel Methner

J Mol Med (Berl) 2020; 98(6): 849–862. Published online 2020 May 11. doi: 10.1007/s00109-020-01914-x

PMCID:: PMC7297831

Abstract Article PDF–2.4M

Select item 47162984.

BAX inhibitor-1 is a Ca²⁺ channel critically important for immune cell function and survival

D Lisak, T Schacht, A Gawlitza, P Albrecht, O Aktas, B Koop, M Gliem, H H Hofstetter, K Zanger, G Bultynck, J B Parys, H De Smedt, T Kindler, P Adams-Quack, M Hahn, A Waisman, J C Reed, N Hövelmeyer, A Methner

Cell Death Differ. 2016 Feb; 23(2): 358–368. Published online 2015 Oct 16. doi: 10.1038/cdd.2015.115

PMCID:: PMC4716298

Abstract Article PDF–3.4M

Select item 38449655.

The protective role of Bax Inhibitor-1 against chronic mild stress through the inhibition of monoamine oxidase A

Hwa-Young Lee, Geum-Hwa Lee, Anu Marahatta, Shun-Mei Lin, Mi-Rin Lee, Kyu Yun Jang, Kyung Min Kim, Hee Jae Lee, Jae-Won Lee, Tarique Rajasaheb Bagalkot, Young-Chul Chung, Yong-Chul Lee, Hyung-Ryong Kim, Han-Jung Chae

Sci Rep. 2013; 3: 3398. Published online 2013 Dec 2. doi: 10.1038/srep03398

PMCID:: PMC3844965

Abstract Article PDF–1.6M

Select item 31341616.

Bax inhibitor 1, a modulator of calcium homeostasis, confers affective resilience

Joshua G. Hunsberger, Rodrigo Machado-Vieira, Daniel R. Austin, Carlos Zarate, De-Maw Chuang, Guang Chen, John C. Reed, Husseini K. Manji

Brain Res. Author manuscript; available in PMC 2012 Jul 27.

Published in final edited form as: Brain Res. 2011 Jul 27; 1403: 19–27. Published online 2011 Jun 12. doi: 10.1016/j.brainres.2011.05.067

PMCID:: PMC3134161

Abstract Article PDF–1.5M

Select item 28402887.

NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection

Cordula Hemrajani, Cedric N. Berger, Keith S. Robinson, Olivier Marchès, Aurelie Mousnier, Gad Frankel

Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7): 3129–3134. Published online 2010 Jan 26. doi: 10.1073/pnas.0911609106

PMCID:: PMC2840288

Abstract Article PDF–689K

Select item 14137738.

Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury

Béatrice Bailly-Maitre, Constantino Fondevila, Fady Kaldas, Nathalie Droin, Fréderic Luciano, Jean-Ehrland Ricci, Rhonda Croxton, Maryla Krajewska, Juan M. Zapata, Jerzy W. Kupiec-Weglinski, Douglas Farmer, John C. Reed

Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8): 2809–2814. Published online 2006 Feb 14. doi: 10.1073/pnas.0506854103

PMCID:: PMC1413773

Abstract Article PDF–448K

Select item 100086879.

Transmembrane BAX inhibitor motif containing 6 suppresses presenilin-2 to preserve mitochondrial integrity after myocardial ischemia-reperfusion injury

Li Ma, Lihan Liao, Na Zhou, Huikang Tao, Hao Zhou, Ying Tan, Weidan Chen, Fan Cao, Xinxin Chen

Int J Biol Sci. 2023; 19(4): 1228–1240. Published online 2023 Feb 13. doi: 10.7150/ijbs.81100

PMCID:: PMC10008687

Abstract Article PDF–7.2M

Select item 901098010.

Bax抑制因子1通过促进视神经萎缩蛋白1表达抑制小鼠动脉血管钙化

陈韦任, 杜辉, 钱赓, 周玉杰, 陈韵岱, 马茜, 吴雪萍, 沙媛

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Mar 20; 42(3): 330–337. Chinese. doi: 10.12122/j.issn.1673-4254.2022.03.03

PMCID:: PMC9010980

Abstract Article PDF–2.0M

Select item 803225111.

TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium

Hyun-Kyoung Kim, Geum-Hwa Lee, Kashi Raj Bhattarai, Myung-Shik Lee, Sung Hoon Back, Hyung-Ryong Kim, Han-Jung Chae

Autophagy. 2021; 17(3): 761–778. Published online 2020 Mar 13. doi: 10.1080/15548627.2020.1732161

PMCID:: PMC8032251

Abstract Article PDF–6.1M

Select item 500605712.

Effect of BI-1 on insulin resistance through regulation of CYP2E1

Geum-Hwa Lee, Kyoung-Jin Oh, Hyung-Ryong Kim, Hye-Sook Han, Hwa-Young Lee, Keun-Gyu Park, Ki-Hoan Nam, Seung-Hoi Koo, Han-Jung Chae

Sci Rep. 2016; 6: 32229. Published online 2016 Aug 31. doi: 10.1038/srep32229

Correction in:: Sci Rep. 2018; 8: 17990.

PMCID:: PMC5006057

Abstract Article PDF–2.5M

Select item 490629413.

Bax Inhibitor-1 regulates hepatic lipid accumulation via ApoB secretion

Hwa Young Lee, Geum-Hwa Lee, Kashi Raj Bhattarai, Byung-Hyun Park, Seung-Hoi Koo, Hyung-Ryong Kim, Han Jung Chae

Sci Rep. 2016; 6: 27799. Published online 2016 Jun 14. doi: 10.1038/srep27799

Correction in:: Sci Rep. 2023; 13: 22864.

PMCID:: PMC4906294

Abstract Article PDF–3.1M

Select item 397324014.

BAX inhibitor-1-associated V-ATPase glycosylation enhances collagen degradation in pulmonary fibrosis

M-R Lee, G-H Lee, H-Y Lee, D-S Kim, M J Chung, Y C Lee, H-R Kim, H-J Chae

Cell Death Dis. 2014 Mar; 5(3): e1113. Published online 2014 Mar 13. doi: 10.1038/cddis.2014.86

PMCID:: PMC3973240

Abstract Article PDF–5.5M

Select item 336056015.

Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy

Renata Sano, Ying-Chen Claire Hou, Michael Hedvat, Ricardo G. Correa, Chih-Wen Shu, Maryla Krajewska, Paul W. Diaz, Craig M. Tamble, Giovanni Quarato, Roberta A. Gottlieb, Masaya Yamaguchi, Victor Nizet, Russell Dahl, David D. Thomas, Stephen W. Tait, Douglas R. Green, Paul B. Fisher, Shu-Ichi Matsuzawa, John C. Reed

Genes Dev. 2012 May 15; 26(10): 1041–1054. doi: 10.1101/gad.184325.111

PMCID:: PMC3360560

Abstract Article PDF–1.5M

Select item 326841416.

The C Terminus of Bax Inhibitor-1 Forms a Ca²⁺-permeable Channel Pore

Geert Bultynck, Santeri Kiviluoto, Nadine Henke, Hristina Ivanova, Lars Schneider, Volodymyr Rybalchenko, Tomas Luyten, Koen Nuyts, Wim De Borggraeve, Ilya Bezprozvanny, Jan B. Parys, Humbert De Smedt, Ludwig Missiaen, Axel Methner

J Biol Chem. 2012 Jan 20; 287(4): 2544–2557. Published online 2011 Nov 28. doi: 10.1074/jbc.M111.275354

PMCID:: PMC3268414

Abstract Article PDF–3.0M

Select item 313705017.

Enhanced Lysosomal Activity Is Involved in Bax Inhibitor-1-induced Regulation of the Endoplasmic Reticulum (ER) Stress Response and Cell Death against ER Stress: INVOLVEMENT OF VACUOLAR H⁺-ATPASE (V-ATPASE)

Geum-Hwa Lee, Do-Sung Kim, Hyung-Tae Kim, Jung-Wook Lee, Chin-Ha Chung, Taeho Ahn, Jung Min Lim, In-Ki Kim, Han-Jung Chae, Hyung-Ryong Kim

J Biol Chem. 2011 Jul 15; 286(28): 24743–24753. Published online 2011 May 17. doi: 10.1074/jbc.M110.167734

PMCID:: PMC3137050

Abstract Article PDF–2.2M

Select item 283807118.

Bax Inhibitor 1 Increases Cell Adhesion through Actin Polymerization: Involvement of Calcium and Actin Binding

Geum-Hwa Lee, Taeho Ahn, Do-Sung Kim, Seoung Ju Park, Yong Chul Lee, Wan Hee Yoo, Sung Jun Jung, Jae-Seong Yang, Sanguk Kim, Andras Muhlrad, Young-Rok Seo, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae

Mol Cell Biol. 2010 Apr; 30(7): 1800–1813. Published online 2010 Feb 1. doi: 10.1128/MCB.01357-09

PMCID:: PMC2838071

Abstract Article PDF–3.5M

Select item 847645019.

TMBIM6 regulates redox-associated posttranslational modifications of IRE1α and ER stress response failure in aging mice and humans

Kashi Raj Bhattarai, Hyun-Kyoung Kim, Manoj Chaudhary, Mohammad Mamun Ur Rashid, Jisun Kim, Hyung-Ryong Kim, Han-Jung Chae

Redox Biol. 2021 Nov; 47: 102128. Published online 2021 Sep 9. doi: 10.1016/j.redox.2021.102128

PMCID:: PMC8476450

Abstract Article PDF–16M

Select item 301925820.

Endoplasmic Reticulum Protein BI-1 Modulates Unfolded Protein Response Signaling and Protects Against Stroke and Traumatic Brain Injury

Maryla Krajewska, Lucy Xu, Wenjie Xu, Stan Krajewski, Christina L. Kress, Janice Cui, Li Yang, Fumitoshi Irie, Yu Yamaguchi, Stuart A. Lipton, John C. Reed

Brain Res. Author manuscript; available in PMC 2012 Jan 25.

Published in final edited form as: Brain Res. 2011 Jan 25; 1370: 227–237. Published online 2010 Nov 12. doi: 10.1016/j.brainres.2010.11.015

PMCID:: PMC3019258

Abstract Article PDF–1.0M

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PMC Links for Gene (Select 110213) (41)
PMC
MAG: hypothetical protein B6D60_00420 [candidate division KSB1 bacterium 4484_87...
MAG: hypothetical protein B6D60_00420 [candidate division KSB1 bacterium 4484_87]
gi|1176173703|gb|OQX89007.1||gnl|WG N|B6D60_00420

Protein
MAG: ribonuclease HIII [candidate division KSB1 bacterium 4484_87]
MAG: ribonuclease HIII [candidate division KSB1 bacterium 4484_87]
gi|1176173692|gb|OQX88996.1||gnl|WG N|B6D60_00365

Protein
Mus musculus transmembrane BAX inhibitor motif containing 6 (Tmbim6), transcript...
Mus musculus transmembrane BAX inhibitor motif containing 6 (Tmbim6), transcript variant 2, mRNA
gi|283945626|ref|NM_001171035.1|

Nucleotide
bax inhibitor 1 isoform X1 [Mus musculus]
bax inhibitor 1 isoform X1 [Mus musculus]
gi|1907109024|ref|XP_036014961.1|

Protein

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