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Select item 78092551.

A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress

Xia Li, Sha Sun, Suhila Appathurai, Arunkumar Sundaram, Rachel Plumb, Malaiyalam Mariappan

Cell Rep. Author manuscript; available in PMC 2021 Jan 15.

Published in final edited form as: Cell Rep. 2020 Dec 29; 33(13): 108563. doi: 10.1016/j.celrep.2020.108563

PMCID:: PMC7809255

Article PDF–1.7M

Select item 34995402.

Role of Human Sec63 in Modulating the Steady-State Levels of Multi-Spanning Membrane Proteins

Andreas Mades, Katherina Gotthardt, Karin Awe, Jens Stieler, Tatjana Döring, Sabine Füser, Reinhild Prange

PLoS One. 2012; 7(11): e49243. Published online 2012 Nov 15. doi: 10.1371/journal.pone.0049243

PMCID:: PMC3499540

Article PDF–1.0M

Select item 12213903.

Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction.

C P Ponting

Biochem J. 2000 Oct 15; 351(Pt 2): 527–535.

PMCID:: PMC1221390

Summary PDF–604K

Select item 101505314.

Activation of ACLY by SEC63 deploys metabolic reprogramming to facilitate hepatocellular carcinoma metastasis upon endoplasmic reticulum stress

Chenyu Hu, Zechang Xin, Xiaoyan Sun, Yang Hu, Chunfeng Zhang, Rui Yan, Yuying Wang, Min Lu, Jing Huang, Xiaojuan Du, Baocai Xing, Xiaofeng Liu

J Exp Clin Cancer Res. 2023; 42: 108. Published online 2023 May 1. doi: 10.1186/s13046-023-02656-7

PMCID:: PMC10150531

Article PDF–14M

Select item 41278115.

Secondary and tertiary structure modeling reveals effects of novel mutations in polycystic liver disease genes PRKCSH and SEC63

E Waanders, H Venselaar, RHM te Morsche, DB de Koning, PS Kamath, VE Torres, S Somlo, JPH Drenth

Clin Genet. Author manuscript; available in PMC 2014 Aug 11.

Published in final edited form as: Clin Genet. 2010 Jul; 78(1): 47–56. Published online 2010 Jan 20. doi: 10.1111/j.1399-0004.2009.01353.x

PMCID:: PMC4127811

Article PDF–291K

Select item 35089946.

Loss of Heterozygosity Is Present in SEC63 Germline Carriers with Polycystic Liver Disease

Manoe J. Janssen, Jody Salomon, René H. M. te Morsche, Joost P. H. Drenth

PLoS One. 2012; 7(11): e50324. Published online 2012 Nov 28. doi: 10.1371/journal.pone.0050324

PMCID:: PMC3508994

Article PDF–334K

Select item 54491877.

The Sec61 translocon limits IRE1α signaling during the unfolded protein response

Arunkumar Sundaram, Rachel Plumb, Suhila Appathurai, Malaiyalam Mariappan

eLife. 2017; 6: e27187. Published online 2017 May 15. doi: 10.7554/eLife.27187

PMCID:: PMC5449187

Article PDF–4.3M

Select item 83849958.

Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth

Johanna M. Huusko, Heli Tiensuu, Antti M. Haapalainen, Anu Pasanen, Pinja Tissarinen, Minna K. Karjalainen, Ge Zhang, Kaare Christensen, Kelli K. Ryckman, Bo Jacobsson, Jeffrey C. Murray, Stephen F. Kingsmore, Mikko Hallman, Louis J. Muglia, Mika Rämet

Sci Rep. 2021; 11: 17115. Published online 2021 Aug 24. doi: 10.1038/s41598-021-96374-9

PMCID:: PMC8384995

Article PDF–2.6M

Select item 45131209.

Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum

Stefan Schorr, Marie-Christine Klein, Igor Gamayun, Armin Melnyk, Martin Jung, Nico Schäuble, Qian Wang, Birgit Hemmis, Florian Bochen, Markus Greiner, Pavel Lampel, Sabine Katharina Urban, Sarah Hassdenteufel, Johanna Dudek, Xing-Zhen Chen, Richard Wagner, Adolfo Cavalié, Richard Zimmermann

J Biol Chem. 2015 Jul 24; 290(30): 18621–18635. Published online 2015 Jun 17. doi: 10.1074/jbc.M115.636639

PMCID:: PMC4513120

Article PDF–2.7M

Select item 594645610.

Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier

Sarah Haßdenteufel, Nicholas Johnson, Adrienne W. Paton, James C. Paton, Stephen High, Richard Zimmermann

Cell Rep. 2018 May 1; 23(5): 1373–1386. Published online 2018 May 2. doi: 10.1016/j.celrep.2018.03.122

PMCID:: PMC5946456

Article PDF–3.7M

Select item 185491611.

Selective Translational Repression of Truncated Proteins from Frameshift Mutation-Derived mRNAs in Tumors

Kwon Tae You, Long Shan Li, Nam-Gyun Kim, Hyun Ju Kang, Kwi Hye Koh, Yong-Joon Chwae, Kyoung Mi Kim, Yoon Ki Kim, Sung Mi Park, Sung Key Jang, Hoguen Kim

PLoS Biol. 2007 May; 5(5): e109. Published online 2007 Apr 24. doi: 10.1371/journal.pbio.0050109

PMCID:: PMC1854916

Article PDF–649K

Select item 407421512.

Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells

Sven Lang, Julia Benedix, Sorin V. Fedeles, Stefan Schorr, Claudia Schirra, Nico Schäuble, Carolin Jalal, Markus Greiner, Sarah Haßdenteufel, Jörg Tatzelt, Birgit Kreutzer, Ludwig Edelmann, Elmar Krause, Jens Rettig, Stefan Somlo, Richard Zimmermann, Johanna Dudek

J Cell Sci. 2012 Apr 15; 125(8): 1958–1969. doi: 10.1242/jcs.096727

PMCID:: PMC4074215

Article

Select item 558887313.

Human GW182 Paralogs are the Central Organizers for RNA-Mediated Control of Transcription

Jessica A. Hicks, Liande Li, Masayuki Matsui, Yongjun Chu, Oleg Volkov, Krystal C. Johnson, David R. Corey

Cell Rep. Author manuscript; available in PMC 2017 Sep 7.

Published in final edited form as: Cell Rep. 2017 Aug 15; 20(7): 1543–1552. doi: 10.1016/j.celrep.2017.07.058

PMCID:: PMC5588873

Article PDF–1.3M

Select item 470715814.

SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation

Ming Wang, Jing Sang, Yanhua Ren, Kejia Liu, Xinyi Liu, Jian Zhang, Haolu Wang, Jian Wang, Amir Orian, Jie Yang, Jing Yi

Protein Cell. 2016 Jan; 7(1): 63–77. Published online 2015 Oct 28. doi: 10.1007/s13238-015-0216-7

PMCID:: PMC4707158

Article PDF–1.3M

Select item 579419015.

Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome

Soham Gupta, Päivi Ylä-Anttila, Simone Callegari, Ming-Han Tsai, Henri-Jacques Delecluse, Maria G. Masucci

PLoS Pathog. 2018 Jan; 14(1): e1006852. Published online 2018 Jan 22. doi: 10.1371/journal.ppat.1006852

PMCID:: PMC5794190

Article PDF–7.4M

Select item 962397916.

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality

Arti T. Navare, Fred D. Mast, Jean Paul Olivier, Thierry Bertomeu, Maxwell L. Neal, Lindsay N. Carpp, Alexis Kaushansky, Jasmin Coulombe-Huntington, Mike Tyers, John D. Aitchison

J Cell Biol. 2022 Nov 7; 221(11): e202011050. Published online 2022 Oct 28. doi: 10.1083/jcb.202011050

PMCID:: PMC9623979

Article PDF–3.7M

Select item 554619817.

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Joanna K. Lempiäinen, Einari A. Niskanen, Kaisa-Mari Vuoti, Riikka E. Lampinen, Helka Göös, Markku Varjosalo, Jorma J. Palvimo

Mol Cell Proteomics. 2017 Aug; 16(8): 1462–1474. Published online 2017 Jun 13. doi: 10.1074/mcp.M117.067488

PMCID:: PMC5546198

Article PDF–3.1M

Select item 352727618.

A Synthetic Interaction Screen Identifies Factors Selectively Required for Proliferation and TERT Transcription in p53-Deficient Human Cancer Cells

Li Xie, Claude Gazin, Sung Mi Park, Lihua J. Zhu, Marie-anne Debily, Ellen L. W. Kittler, Maria L. Zapp, David Lapointe, Stephane Gobeil, Ching-Man Virbasius, Michael R. Green

PLoS Genet. 2012 Dec; 8(12): e1003151. Published online 2012 Dec 20. doi: 10.1371/journal.pgen.1003151

PMCID:: PMC3527276

Article PDF–1.8M

Select item 669962319.

The human regulatory protein Ki-1/57 is a target of SUMOylation and affects PML nuclear bodies formation

Ângela Saito, Edmarcia E. Souza, Fernanda C. Costa, Gabriela V. Meirelles, Kaliandra A. Gonçalves, Marcos T. Santos, Gustavo C. Bressan, Mark E. McComb, Catherine E. Costello, Stephen A. Whelan, Jörg Kobarg

J Proteome Res. Author manuscript; available in PMC 2019 Aug 19.

Published in final edited form as: J Proteome Res. 2017 Sep 1; 16(9): 3147–3157. Published online 2017 Jul 31. doi: 10.1021/acs.jproteome.7b00001