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Select item 111483291.

The human alpha7 nicotinic acetylcholine receptor is a host target for the rabies virus glycoprotein

Brittany C. V. O’Brien, Shelly Thao, Lahra Weber, Helen L. Danielson, Agatha D. Boldt, Karsten Hueffer, Maegan M. Weltzin

Front Cell Infect Microbiol. 2024; 14: 1394713. Published online 2024 May 21. doi: 10.3389/fcimb.2024.1394713

PMCID:: PMC11148329

Abstract Article PDF–4.4M

Select item 100417672.

α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect

Huiyang Liu, Xiaomei Zhang, Peng Shi, Jiyuan Yuan, Qiang Jia, Chao Pi, Tao Chen, Linjin Xiong, Jinglin Chen, Jia Tang, Ruxu Yue, Zerong Liu, Hongping Shen, Ying Zuo, Yumeng Wei, Ling Zhao

J Neuroinflammation. 2023; 20: 84. Published online 2023 Mar 27. doi: 10.1186/s12974-023-02768-z

PMCID:: PMC10041767

Abstract Article PDF–2.2M

Select item 98501333.

The holistic approach to the CHRNA7 gene, hsa-miR-3158-5p, and 15q13.3 hotspot CNVs in migraineurs

Sedat Yasin, Şenay Görücü Yılmaz, Sırma Geyik, Sibel Oğuzkan Balcı

Mol Pain. 2023; 19: 17448069231152104. Published online 2023 Jan 17. doi: 10.1177/17448069231152104

PMCID:: PMC9850133

Abstract Article PDF–1.6M

Select item 89291004.

Screening for Copy Number Variations of the 15q13.3 Hotspot in CHRNA7 Gene and Expression in Patients with Migraines

Mehmet Fatih Özaltun, Sırma Geyik, Şenay Görücü Yılmaz

Curr Issues Mol Biol. 2021 Sep; 43(2): 1090–1113. Published online 2021 Sep 7. doi: 10.3390/cimb43020078

PMCID:: PMC8929100

Abstract Article PDF–927K

Select item 88315965.

Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor

Vasyl Bondarenko, Marta M. Wells, Qiang Chen, Tommy S. Tillman, Kevin Singewald, Matthew J. Lawless, Joel Caporoso, Nicole Brandon, Jonathan A. Coleman, Sunil Saxena, Erik Lindahl, Yan Xu, Pei Tang

Nat Commun. 2022; 13: 793. Published online 2022 Feb 10. doi: 10.1038/s41467-022-28400-x

PMCID:: PMC8831596

Abstract Article PDF–1.7M

Select item 83173526.

Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7

Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner, John N. Constantino, Kristen L. Kroll

BMC Biol. 2021; 19: 147. Published online 2021 Jul 28. doi: 10.1186/s12915-021-01080-7

PMCID:: PMC8317352

Abstract Article PDF–14M

Select item 81833927.

Nicotinic α7 Acetylcholine Receptor (α7nAChR) in Human Airway Smooth Muscle

Niyati A. Borkar, Benjamin Roos, Y.S. Prakash, Venkatachalem Sathish, Christina M. Pabelick

Arch Biochem Biophys. Author manuscript; available in PMC 2022 Jul 30.

Published in final edited form as: Arch Biochem Biophys. 2021 Jul 30; 706: 108897. Published online 2021 May 15. doi: 10.1016/j.abb.2021.108897

PMCID:: PMC8183392

Abstract Article PDF–1.5M

Select item 80119278.

Thermodynamics and Kinetics of Ion Permeation in Wild-Type and Mutated Open Active Conformation of the Human α7 Nicotinic Receptor

Grazia Cottone, Letizia Chiodo, Luca Maragliano

J Chem Inf Model. 2020 Oct 26; 60(10): 5045–5056. Published online 2020 Aug 17. doi: 10.1021/acs.jcim.0c00549

PMCID:: PMC8011927

Abstract Article PDF–4.7M

Select item 77467199.

The neuroprotective effects of activated α7 nicotinic acetylcholine receptor against mutant copper–zinc superoxide dismutase 1-mediated toxicity

Taisei Ito, Masatoshi Inden, Tomoyuki Ueda, Yuta Asaka, Hisaka Kurita, Isao Hozumi

Sci Rep. 2020; 10: 22157. Published online 2020 Dec 17. doi: 10.1038/s41598-020-79189-y

PMCID:: PMC7746719

Abstract Article PDF–6.0M

Select item 741140410.

Expression levels of the α7 nicotinic acetylcholine receptor in the brains of patients with Alzheimer's disease and their effect on synaptic proteins in SH-SY5Y cells

Jia-Mou Ren, Shu-Li Zhang, Xiao-Ling Wang, Zhi-Zhong Guan, Xiao-Lan Qi

Mol Med Rep. 2020 Sep; 22(3): 2063–2075. Published online 2020 Jun 18. doi: 10.3892/mmr.2020.11253

PMCID:: PMC7411404

Abstract Article PDF–1.4M

Select item 739719611.

Profile of the Nicotinic Cholinergic Receptor Alpha 7 Subunit Gene Expression is Associated with Response to Varenicline Treatment

Juliana Rocha Santos, Paulo Roberto Xavier Tomaz, Jaqueline Ribeiro Scholz, Patrícia Viviane Gaya, Tânia Ogawa Abe, José Eduardo Krieger, Alexandre Costa Pereira, Paulo Caleb Júnior de Lima Santos

Genes (Basel) 2020 Jul; 11(7): 746. Published online 2020 Jul 6. doi: 10.3390/genes11070746

PMCID:: PMC7397196

Abstract Article PDF–437K

Select item 724271612.

Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3β4 and α7 nicotinic acetylcholine receptors

Madhan Kumar Mohan, Nikita Abraham, Rajesh R P, Benjamin Franklin Jayaseelan, Lotten Ragnarsson, Richard J. Lewis, Siddhartha P. Sarma

J Biol Chem. 2020 May 15; 295(20): 7096–7112. Published online 2020 Mar 31. doi: 10.1074/jbc.RA119.012098

Correction in:: J Biol Chem. 2020 Jun 26; 295(26): 8872.

PMCID:: PMC7242716

Abstract Article PDF–4.3M

Select item 706878513.

Nicotinic Acetylcholine Receptor Expression and Susceptibility to Cholinergic Immunomodulation in Human Monocytes of Smoking Individuals

Esmerij P. van der Zanden, Francisca W. Hilbers, Caroline Verseijden, Rene M. van den Wijngaard, Mike Skynner, Kevin Lee, Luis Ulloa, Guy E. Boeckxstaens, Wouter J. de Jonge

Neuroimmunomodulation. 2012 Mar; 19(4): 255–265. Published online 2012 Mar 21. doi: 10.1159/000335185

PMCID:: PMC7068785

Abstract Article

Select item 653122314.

Mining and validating the expression pattern and prognostic value of acetylcholine receptors in non-small cell lung cancer

Guoyuan Ma, Delin Ji, Xiao Qu, Shaorui Liu, Xudong Yang, Guanghui Wang, Qi Liu, Jiajun Du

Medicine (Baltimore) 2019 May; 98(20): e15555. Published online 2019 May 17. doi: 10.1097/MD.0000000000015555

PMCID:: PMC6531223

Abstract Article PDF–317K

Select item 647538815.

Uniquely human CHRFAM7A gene increases the hematopoietic stem cell reservoir in mice and amplifies their inflammatory response

Todd W. Costantini, Theresa W. Chan, Olga Cohen, Simone Langness, Sabrina Treadwell, Elliot Williams, Brian P. Eliceiri, Andrew Baird

Proc Natl Acad Sci U S A. 2019 Apr 16; 116(16): 7932–7940. Published online 2019 Apr 3. doi: 10.1073/pnas.1821853116

PMCID:: PMC6475388

Abstract Article PDF–1.8M

Select item 627347916.

CHRNA7 Deletions are Enriched in Risperidone-Treated Children and Adolescents

Madelyn A. Gillentine, Janson J. White, Christopher M. Grochowski, James R. Lupski, Christian P. Schaaf, Chadi A. Calarge

J Affect Disord. Author manuscript; available in PMC 2019 Apr 15.

Published in final edited form as: J Affect Disord. 2018 Oct 15; 239: 247–252. Published online 2018 Jul 11. doi: 10.1016/j.jad.2018.07.017

PMCID:: PMC6273479

Abstract Article PDF–717K

Select item 613095417.

Interaction of the α7-nicotinic subunit with its human-specific duplicated dupα7 isoform in mammalian cells: Relevance in human inflammatory responses

María C. Maldifassi, Carolina Martín-Sánchez, Gema Atienza, José L. Cedillo, Francisco Arnalich, Anna Bordas, Francisco Zafra, Cecilio Giménez, María Extremera, Jaime Renart, Carmen Montiel

J Biol Chem. 2018 Sep 7; 293(36): 13874–13888. Published online 2018 Jul 13. doi: 10.1074/jbc.RA118.003443

PMCID:: PMC6130954

Abstract Article PDF–2.1M

Select item 597975218.

Persistent activation of α7 nicotinic ACh receptors associated with stable induction of different desensitized states

Roger L Papke, Clare Stokes, M Imad Damaj, Ganesh A Thakur, Khan Manther, Millet Treinin, Deniz Bagdas, Abhijit R Kulkarni, Nicole A Horenstein

Br J Pharmacol. 2018 Jun; 175(11): 1838–1854. Published online 2017 Jun 8. doi: 10.1111/bph.13851

PMCID:: PMC5979752

Abstract Article PDF–1.4M

Select item 581819019.

An allosteric binding site of the α7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein

Florian Delbart, Marijke Brams, Fabian Gruss, Sam Noppen, Steve Peigneur, Sandro Boland, Patrick Chaltin, Jose Brandao-Neto, Frank von Delft, Wouter G. Touw, Robbie P. Joosten, Sandra Liekens, Jan Tytgat, Chris Ulens

J Biol Chem. 2018 Feb 16; 293(7): 2534–2545. Published online 2017 Dec 13. doi: 10.1074/jbc.M117.815316