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Items: 1 to 20 of 63

1.
Human Tobacco Smokers in Early Abstinence Have Higher Levels of β2* Nicotinic Acetylcholine Receptors than Nonsmokers
Julie K. Staley, Suchitra Krishnan-Sarin, Kelly P. Cosgrove, Erica Krantzler, Erin Frohlich, Edward Perry, Joel A. Dubin, Kristina Estok, Eric Brenner, Ronald M. Baldwin, Gilles D. Tamagnan, John P. Seibyl, Peter Jatlow, Marina R. Picciotto, Edythe D. London, Stephanie O'Malley, Christopher H. van Dyck
J Neurosci. 2006 Aug 23; 26(34): 8707–8714. doi: 10.1523/JNEUROSCI.0546-06.2006
PMCID:
PMC6674379
AbstractArticlePDF–282K
2.
Age-related decline in nicotinic receptor availability with [123I]5-IA-85380 SPECT
Effie M. Mitsis, Kelly P. Cosgrove, Julie K. Staley, Frederic Bois, Erin B. Frohlich, Gilles D. Tamagnan, Kristina M. Estok, John P. Seibyl, Christopher H. van Dyck
Neurobiol Aging. Author manuscript; available in PMC 2012 Dec 17.
Published in final edited form as: Neurobiol Aging. 2009 Sep; 30(9): 1490–1497. Published online 2008 Feb 1. doi: 10.1016/j.neurobiolaging.2007.12.008
PMCID:
PMC3523217
AbstractArticlePDF–470K
3.
Varenicline for Smoking Cessation: Nausea Severity and Variation in Nicotinic Receptor Genes
Gary E. Swan, Harold S. Javitz, Lisa M. Jack, Jennifer Wessel, Martha Michel, David A. Hinds, Renee P. Stokowksi, Jennifer B. McClure, Sheryl L. Catz, Julie Richards, Susan M. Zbikowski, Mona Deprey, Tim McAfee, David V. Conti, Andrew W. Bergen
Pharmacogenomics J. Author manuscript; available in PMC 2013 Feb 1.
Published in final edited form as: Pharmacogenomics J. 2012 Aug; 12(4): 349–358. Published online 2011 May 24. doi: 10.1038/tpj.2011.19
PMCID:
PMC3405554
AbstractArticlePDF–352K
4.
NMR Structure of the Transmembrane Domain of the n-Acetylcholine Receptor β2 Subunit
Vasyl Bondarenko, Tommy Tillman, Yan Xu, Pei Tang
Biochim Biophys Acta. Author manuscript; available in PMC 2011 Aug 1.
Published in final edited form as: Biochim Biophys Acta. 2010 Aug; 1798(8): 1608–1614. Published online 2010 May 2. doi: 10.1016/j.bbamem.2010.04.014
PMCID:
PMC2885491
AbstractArticlePDF–3.0M
5.
Beta2* nicotinic acetylcholine receptors modulate pain sensitivity in acutely abstinent tobacco smokers
Kelly P. Cosgrove, Irina Esterlis, Sherry McKee, Frederic Bois, David Alagille, Gilles D. Tamagnan, John P. Seibyl, Suchitra Krishnan-Sarin, Julie K. Staley
Nicotine Tob Res. 2010 May; 12(5): 535–539. Published online 2010 Apr 6. doi: 10.1093/ntr/ntq040
PMCID:
PMC2861889
AbstractArticlePDF–100K
6.
NICOTINIC ACETYLCHOLINE RECEPTOR β2 SUBUNIT (CHRNB2) GENE AND SHORT-TERM ABILITY TO QUIT SMOKING IN RESPONSE TO NICOTINE PATCH
Kenneth A. Perkins, Caryn Lerman, Melissa Mercincavage, Carolyn A. Fonte, Jessica L. Briski
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2010 Oct 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 Oct; 18(10): 2608–2612. Published online 2009 Sep 15. doi: 10.1158/1055-9965.EPI-09-0166
PMCID:
PMC2759850
AbstractArticlePDF–324K
7.
Nicotinic acetylcholine receptor β2 subunit gene implicated in a systems-based candidate gene study of smoking cessation
David V. Conti, Won Lee, Dalin Li, Jinghua Liu, David Van Den Berg, Paul D. Thomas, Andrew W. Bergen, Gary E. Swan, Rachel F. Tyndale, Neal L. Benowitz, Caryn Lerman
Hum Mol Genet. 2008 Sep 15; 17(18): 2834–2848. Published online 2008 Jul 1. doi: 10.1093/hmg/ddn181
PMCID:
PMC2525499
AbstractArticlePDF–465K
8.
Nucleotide sequence of the human nicotinic acetylcholine receptor beta 2 subunit gene.
R Anand, J Lindstrom
Nucleic Acids Res. 1990 Jul 25; 18(14): 4272. doi: 10.1093/nar/18.14.4272
PMCID:
PMC331211
SummaryPage BrowsePDF–167K
9.
Sleep-related hypermotor epilepsy associated mutations uncover important kinetic roles of α4β2- nicotinic acetylcholine receptor intracellular structures
Maegan M. Weltzin, Andrew A. George, Ronald J. Lukas, Paul Whiteaker
PLoS One. 2021; 16(3): e0247825. Published online 2021 Mar 3. doi: 10.1371/journal.pone.0247825
PMCID:
PMC7928491
AbstractArticlePDF–4.5M
10.
Association of idiopathic generalized epilepsy with polymorphisms in the neuronal nicotinic acetylcholine receptor subunits
Cheng‐Chun Lee, I‐Ching Chou, Chang‐Hai Tsai, Lei Wan, Yu‐An Shu, Yuhsin Tsai, Tsai‐Chung Li, Fuu‐Jen Tsai
J Clin Lab Anal. 2007; 21(2): 67–70. Published online 2007 Mar 26. doi: 10.1002/jcla.20155
PMCID:
PMC6648989
AbstractArticlePDF–119K
11.
Structural principles of distinct assemblies of the human α4β2 nicotinic receptor
Richard M. Walsh, Jr., Soung-Hun Roh, Anant Gharpure, Claudio L. Morales-Perez, Jinfeng Teng, Ryan E. Hibbs
Nature. Author manuscript; available in PMC 2018 Nov 2.
Published in final edited form as: Nature. 2018 May; 557(7704): 261–265. Published online 2018 May 2. doi: 10.1038/s41586-018-0081-7
PMCID:
PMC6132059
AbstractArticlePDF–2.9M
12.
The fifth subunit of the (α4β2)2β2 nicotinic ACh receptor modulates maximal ACh responses
Karina New, Silvia Garcia Del Villar, Simone Mazzaferro, Constanza Alcaino, Isabel Bermudez
Br J Pharmacol. 2018 Jun; 175(11): 1822–1837. Published online 2017 Jul 14. doi: 10.1111/bph.13905
PMCID:
PMC5978951
AbstractArticlePDF–1.5M
13.
Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2)2-type nicotinic acetylcholine receptor responses
Ze-Jun Wang, Farah Deba, Tasnim S. Mohamed, David C. Chiara, Kara Ramos, Ayman K. Hamouda
J Biol Chem. 2017 Jun 16; 292(24): 9988–10001. Published online 2017 Apr 26. doi: 10.1074/jbc.M116.771246
PMCID:
PMC5473250
AbstractArticlePDF–4.9M
14.
The E Loop of the Transmitter Binding Site Is a Key Determinant of the Modulatory Effects of Physostigmine on Neuronal Nicotinic α4β2 Receptors
Xiaochun Jin, Megan M. McCollum, Allison L. Germann, Gustav Akk, Joe Henry Steinbach
Mol Pharmacol. 2017 Feb; 91(2): 100–109. Published online 2017 Feb. doi: 10.1124/mol.116.106484
PMCID:
PMC5267520
AbstractArticlePDF–688K
15.
X-ray structure of the human a4ß2 nicotinic receptor
Claudio L. Morales-Perez, Colleen M. Noviello, Ryan E. Hibbs
Nature. Author manuscript; available in PMC 2017 Apr 3.
Published in final edited form as: Nature. 2016 Oct 20; 538(7625): 411–415. Published online 2016 Oct 3. doi: 10.1038/nature19785
PMCID:
PMC5161573
AbstractArticlePDF–3.7M
16.
Differential α4(+)/(−)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms
Linda M. Lucero, Maegan M. Weltzin, J. Brek Eaton, John F. Cooper, Jon M. Lindstrom, Ronald J. Lukas, Paul Whiteaker
J Biol Chem. 2016 Jan 29; 291(5): 2444–2459. Published online 2015 Dec 7. doi: 10.1074/jbc.M115.684373
PMCID:
PMC4732226
AbstractArticlePDF–3.2M
17.
Brain Nicotinic Acetylcholine Receptor Availability and Response to Smoking Cessation Treatment A Randomized Trial
Arthur L. Brody, Alexey G. Mukhin, Michael S. Mamoun, Trinh Luu, Meaghan Neary, Lidia Liang, Jennifer Shieh, Catherine A. Sugar, Jed E. Rose, Mark A. Mandelkern
JAMA Psychiatry. Author manuscript; available in PMC 2015 Nov 5.
Published in final edited form as: JAMA Psychiatry. 2014 Jul 1; 71(7): 797–805. doi: 10.1001/jamapsychiatry.2014.138
PMCID:
PMC4634637
AbstractArticlePDF–881K
18.
An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors
Jingyi Wang, Alexander Kuryatov, Aarati Sriram, Zhuang Jin, Theodore M. Kamenecka, Paul J. Kenny, Jon Lindstrom
J Biol Chem. 2015 May 29; 290(22): 13907–13918. Published online 2015 Apr 13. doi: 10.1074/jbc.M115.646786
PMCID:
PMC4447965
AbstractArticlePDF–1.7M
19.
Structural and Functional Studies of the Modulator NS9283 Reveal Agonist-like Mechanism of Action at α4β2 Nicotinic Acetylcholine Receptors
Jeppe A. Olsen, Philip K. Ahring, Jette S. Kastrup, Michael Gajhede, Thomas Balle
J Biol Chem. 2014 Sep 5; 289(36): 24911–24921. Published online 2014 Jun 30. doi: 10.1074/jbc.M114.568097
PMCID:
PMC4155659
AbstractArticlePDF–1.8M
20.
Treatment for Tobacco Dependence: Effect on Brain Nicotinic Acetylcholine Receptor Density
Arthur L Brody, Alexey G Mukhin, Stephanie Shulenberger, Michael S Mamoun, Maggie Kozman, Jonathan Phuong, Meaghan Neary, Trinh Luu, Mark A Mandelkern
Neuropsychopharmacology. 2013 Jul; 38(8): 1548–1556. Prepublished online 2013 Feb 21. Published online 2013 Mar 20. doi: 10.1038/npp.2013.53
PMCID:
PMC3682149
AbstractArticlePDF–436K

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