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Items: 1 to 20 of 85

1.
Genetic modifiers of radon induced lung cancer risk - A genome-wide interaction study in former uranium miners
Albert Rosenberger, Rayjean J Hung, David C Christiani, Neil E Caporaso, Geoffrey Liu, Stig E Bojesen, Loic Le Marchand, Ch. A. Haiman, Demetrios Albanes, Melinda C Aldrich, Adonina Tardon, G. Fernández-Tardón, Gad Rennert, John K Field, B. Kiemeney, Philip Lazarus, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Hans Brunnsstöm, Gary E Goodman, Jennifer A Doherty, Chu Chen, M Dawn Teare, H-Erich Wichmann, Judith Manz, Angela Risch, Thomas R Muley, Mikael Johansson, Paul Brennan, Maria Teresa Landi, Christopher I Amos, Beate Pesch, Georg Johnen, Thomas Brüning, Heike Bickeböller, Maria Gomolka
Int Arch Occup Environ Health. Author manuscript; available in PMC 2019 Nov 1.
Published in final edited form as: Int Arch Occup Environ Health. 2018 Nov; 91(8): 937–950. Published online 2018 Jul 3. doi: 10.1007/s00420-018-1334-3
PMCID:
PMC6375683
AbstractArticlePDF–495K
2.
Functional Characterization Improves Associations between Rare Non-Synonymous Variants in CHRNB4 and Smoking Behavior
Gabe Haller, Ping Li, Caroline Esch, Simon Hsu, Alison M. Goate, Joe Henry Steinbach
PLoS One. 2014; 9(5): e96753. Published online 2014 May 7. doi: 10.1371/journal.pone.0096753
Correction in:
PLoS One. 2014; 9(6): e99748.
PMCID:
PMC4013067
AbstractArticlePDF–1.9M
3.
Alternative CHRNB4 3′-UTRs Mediate the Allelic Effects of SNP rs1948 on Gene Expression
Xavier Gallego, Ryan J. Cox, James R. Laughlin, Jerry A. Stitzel, Marissa A Ehringer
PLoS One. 2013; 8(5): e63699. Published online 2013 May 14. doi: 10.1371/journal.pone.0063699
PMCID:
PMC3653846
AbstractArticlePDF–1.0M
4.
Carboetomidate Inhibits Alpha4/Beta2 Neuronal Nicotinic Acetylcholine Receptors at Concentrations Affecting Animals
David W. Pierce, Ervin Pejo, Douglas E. Raines, Stuart A. Forman
Anesth Analg. Author manuscript; available in PMC 2013 Jul 1.
Published in final edited form as: Anesth Analg. 2012 Jul; 115(1): 70–72. Published online 2012 Apr 27. doi: 10.1213/ANE.0b013e318254273e
PMCID:
PMC3381859
AbstractArticlePDF–622K
5.
Variants Located Upstream of CHRNB4 on Chromosome 15q25.1 Are Associated with Age at Onset of Daily Smoking and Habitual Smoking
Manav Kapoor, Jen-Chyong Wang, Sarah Bertelsen, Kathy Bucholz, John P. Budde, Anthony Hinrichs, Arpana Agrawal, Andrew Brooks, David Chorlian, Danielle Dick, Victor Hesselbrock, Tatiana Foroud, John Kramer, Samuel Kuperman, Niklas Manz, John Nurnberger, Jr, Bernice Porjesz, John Rice, Jay Tischfield, Xiaoling Xuei, Marc Schuckit, Howard J. Edenberg, Laura J. Bierut, Alison M. Goate
PLoS One. 2012; 7(3): e33513. Published online 2012 Mar 16. doi: 10.1371/journal.pone.0033513
PMCID:
PMC3306405
AbstractArticlePDF–239K
6.
Nicotine-Modulated Subunit Stoichiometry Affects Stability and Trafficking of α3β4 Nicotinic Receptor
Francesca Mazzo, Francesco Pistillo, Giovanni Grazioso, Francesco Clementi, Nica Borgese, Cecilia Gotti, Sara Francesca Colombo
J Neurosci. 2013 Jul 24; 33(30): 12316–12328. doi: 10.1523/JNEUROSCI.2393-13.2013
PMCID:
PMC6618676
AbstractArticlePDF–2.4M
7.
Nicotinic Acetylcholine Receptor α7 and β4 Subunits Contribute to Nicotine-Induced Apoptosis in Periodontal Ligament Stem Cells
So Yeon Kim, Kyung Lhi Kang, Jeong-Chae Lee, Jung Sun Heo
Mol Cells. 2012 Apr 30; 33(4): 343–350. Published online 2012 Feb 29. doi: 10.1007/s10059-012-2172-x
PMCID:
PMC3887805
AbstractArticlePDF–652K
8.
Elucidation of Molecular Impediments in the α6 Subunit for in Vitro Expression of Functional α6β4* Nicotinic Acetylcholine Receptors
Anne B. Jensen, Kirsten Hoestgaard-Jensen, Anders A. Jensen
J Biol Chem. 2013 Nov 22; 288(47): 33708–33721. Published online 2013 Oct 1. doi: 10.1074/jbc.M113.509356
PMCID:
PMC3837116
AbstractArticlePDF–3.0M
9.
Epigenetic screen identifies genotype- specific promoter DNA methylation and oncogenic potential of CHRNB4
David B Scherf, Narek Sarkisyan, Hanna Jacobsson, Rainer Claus, Justo L Bermejo, Barbara Peil, Lei Gu, Thomas Muley, Michael Meister, Hendrik Dienemann, Christoph Plass, Angela Risch
Oncogene. Author manuscript; available in PMC 2014 Jan 11.
Published in final edited form as: Oncogene. 2013 Jul 11; 32(28): 3329–3338. Published online 2012 Sep 3. doi: 10.1038/onc.2012.344
PMCID:
PMC3710305
AbstractArticlePDF–1.1M
10.
Binding Interactions with the Complementary Subunit of Nicotinic Receptors
Angela P. Blum, Ethan B. Van Arnam, Laurel A. German, Henry A. Lester, Dennis A. Dougherty
J Biol Chem. 2013 Mar 8; 288(10): 6991–6997. Published online 2013 Jan 24. doi: 10.1074/jbc.M112.439968
PMCID:
PMC3591609
AbstractArticlePDF–676K
11.
Native α6β4* nicotinic receptors control exocytosis in human chromaffin cells of the adrenal gland
Alberto Pérez-Alvarez, Alicia Hernández-Vivanco, J. Michael McIntosh, Almudena Albillos
FASEB J. 2012 Jan; 26(1): 346–354. doi: 10.1096/fj.11-190223
PMCID:
PMC3250250
AbstractArticle
12.
Increased Sensitivity of the Neuronal Nicotinic Receptor α2 Subunit Causes Familial Epilepsy with Nocturnal Wandering and Ictal Fear
Paolo Aridon, Carla Marini, Chiara Di Resta, Elisa Brilli, Maurizio De Fusco, Fausta Politi, Elena Parrini, Irene Manfredi, Tiziana Pisano, Dario Pruna, Giulia Curia, Carlo Cianchetti, Massimo Pasqualetti, Andrea Becchetti, Renzo Guerrini, Giorgio Casari
Am J Hum Genet. 2006 Aug; 79(2): 342–350. Published online 2006 Jun 26. doi: 10.1086/506459
PMCID:
PMC1559502
AbstractArticlePDF–1.3M
13.
The relationship between CHRNA5/A3/B4 gene cluster polymorphisms and lung cancer risk: An updated meta-analysis and systematic review
Xingxu Yi, Wanzhen Li, Yiyuan Wang, Xueran Chen, Fang Ye, Gengyun Sun, Jingxian Chen
Medicine (Baltimore) 2021 Feb 12; 100(6): e24355. Published online 2021 Feb 12. doi: 10.1097/MD.0000000000024355
PMCID:
PMC7886493
AbstractArticlePDF–1.3M
14.
Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence
Sung-Ha Lee, Woo-Young Ahn, Michał Seweryn, Wolfgang Sadee
BMC Genomics. 2018; 19: 826. Published online 2018 Nov 20. doi: 10.1186/s12864-018-5219-3
PMCID:
PMC6245894
AbstractArticlePDF–817K
15.
The CHRNA5/CHRNA3/CHRNB4 nicotinic receptor regulome: genomic architecture, regulatory variants, and clinical associations
Elizabeth S. Barrie, Katherine Hartmann, Sung-Ha Lee, John T. Frater, Michal Seweryn, Danxin Wang, Wolfgang Sadee
Hum Mutat. Author manuscript; available in PMC 2018 Jan 1.
Published in final edited form as: Hum Mutat. 2017 Jan; 38(1): 112–119. Published online 2016 Nov 7. doi: 10.1002/humu.23135
PMCID:
PMC5154896
AbstractArticlePDF–2.0M
16.
Gene variance in the nicotinic receptor cluster (CHRNA5‐CHRNA3‐CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers
S. Halldén, M. Sjögren, B. Hedblad, G. Engström, V. Hamrefors, J. Manjer, O. Melander
J Intern Med. 2016 Apr; 279(4): 388–398. Published online 2015 Dec 22. doi: 10.1111/joim.12454
PMCID:
PMC5019278
AbstractArticlePDF–234K
17.
Chromosome 15q25 (CHRNA3-CHRNB4) Variation Indirectly Impacts Lung Cancer Risk in Chinese Males
Yalei Zhang, Mei Jiang, Qin Li, Wenhua Liang, Qihua He, Weiqing Chen, Jianxing He
PLoS One. 2016; 11(3): e0149946. Published online 2016 Mar 4. doi: 10.1371/journal.pone.0149946
PMCID:
PMC4778880
AbstractArticlePDF–946K
18.
Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking
Rachel F. Tyndale, Andy Z. X. Zhu, Tony P. George, Paul Cinciripini, Larry W. Hawk, Jr., Robert A. Schnoll, Gary E. Swan, Neal L. Benowitz, Daniel F. Heitjan, Caryn Lerman, PGRN-PNAT Research Group
PLoS One. 2015; 10(5): e0128109. Published online 2015 May 26. doi: 10.1371/journal.pone.0128109
PMCID:
PMC4444267
AbstractArticlePDF–875K
19.
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence
JC Wang, R Grucza, C Cruchaga, AL Hinrichs, S Bertelsen, JP Budde, L Fox, E Goldstein, O Reyes, N Saccone, S Saccone, X Xuei, K Bucholz, S Kuperman, J Nurnberger, Jr, JP Rice, M Schuckit, J Tischfield, V Hesselbrock, B Porjesz, HJ Edenberg, LJ Bierut, AM Goate
Mol Psychiatry. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: Mol Psychiatry. 2009 May; 14(5): 501–510. Published online 2008 Apr 15. doi: 10.1038/mp.2008.42
PMCID:
PMC4381434
AbstractArticlePDF–1.4M
20.
Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers
Amy E. Taylor, Richard W. Morris, Meg E. Fluharty, Johan H. Bjorngaard, Bjørn Olav Åsvold, Maiken E. Gabrielsen, Archie Campbell, Riccardo Marioni, Meena Kumari, Jenni Hällfors, Satu Männistö, Pedro Marques-Vidal, Marika Kaakinen, Alana Cavadino, Iris Postmus, Lise Lotte N. Husemoen, Tea Skaaby, Tarunveer S. Ahluwalia, Jorien L. Treur, Gonneke Willemsen, Caroline Dale, S. Goya Wannamethee, Jari Lahti, Aarno Palotie, Katri Räikkönen, Aliaksei Kisialiou, Alex McConnachie, Sandosh Padmanabhan, Andrew Wong, Christine Dalgård, Lavinia Paternoster, Yoav Ben-Shlomo, Jessica Tyrrell, John Horwood, David M. Fergusson, Martin A. Kennedy, Tim Frayling, Ellen A. Nohr, Lene Christiansen, Kirsten Ohm Kyvik, Diana Kuh, Graham Watt, Johan Eriksson, Peter H. Whincup, Jacqueline M. Vink, Dorret I. Boomsma, George Davey Smith, Debbie Lawlor, Allan Linneberg, Ian Ford, J. Wouter Jukema, Christine Power, Elina Hyppönen, Marjo-Riitta Jarvelin, Martin Preisig, Katja Borodulin, Jaakko Kaprio, Mika Kivimaki, Blair H. Smith, Caroline Hayward, Pål R. Romundstad, Thorkild I. A. Sørensen, Marcus R. Munafò, Naveed Sattar
PLoS Genet. 2014 Dec; 10(12): e1004799. Published online 2014 Dec 4. doi: 10.1371/journal.pgen.1004799
PMCID:
PMC4256159
AbstractArticlePDF–200K

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