PMC Links for Gene (Select 115004) - PMC

Jonny Hertzog, Wen Zhou, Gerissa Fowler, Rachel E Rigby, Anne Bridgeman, Henry TW Blest, Chiara Cursi, Lise Chauveau, Tamara Davenne, Benjamin E Warner, Paul R Kinchington, Philip J Kranzusch, Jan Rehwinkel

EMBO J. 2022 Jul; 41(14): e109217. Published online 2022 Jun 7. doi: 10.15252/embj.2021109217

PMCID:: PMC9289529

Abstract Article PDF–3.5M

Select item 90907446.

Nuclear soluble cGAS senses double-stranded DNA virus infection

Yakun Wu, Kun Song, Wenzhuo Hao, Jack Li, Lingyan Wang, Shitao Li

Commun Biol. 2022; 5: 433. Published online 2022 May 10. doi: 10.1038/s42003-022-03400-1

PMCID:: PMC9090744

Abstract Article PDF–2.7M

Select item 87839407.

Nuclear cGAS: sequestration and beyond

Juli Bai, Feng Liu

Protein Cell. 2022 Feb; 13(2): 90–101. Published online 2021 Aug 9. doi: 10.1007/s13238-021-00869-0

PMCID:: PMC8783940

Abstract Article PDF–2.0M

Select item 87769708.

cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence

Xiaocui Li, Xiaojuan Li, Chen Xie, Sihui Cai, Mengqiu Li, Heping Jin, Shu Wu, Jun Cui, Haiying Liu, Yong Zhao

Protein Cell. 2022 Jan; 13(1): 47–64. Published online 2021 Oct 22. doi: 10.1007/s13238-021-00879-y

PMCID:: PMC8776970

Abstract Article PDF–5.8M

Select item 86409369.

Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells

Patrick J. Flynn, Peter D. Koch, Timothy J. Mitchison

Proc Natl Acad Sci U S A. 2021 Nov 30; 118(48): e2103585118. Published online 2021 Nov 24. doi: 10.1073/pnas.2103585118

PMCID:: PMC8640936

Abstract Article PDF–1.2M

Select item 845008610.

Cooperative DNA binding mediated by KicGAS/ORF52 oligomerization allows inhibition of DNA-induced phase separation and activation of cGAS

Debipreeta Bhowmik, Mingjian Du, Yuan Tian, Siming Ma, Jianjun Wu, Zhijian Chen, Qian Yin, Fanxiu Zhu

Nucleic Acids Res. 2021 Sep 20; 49(16): 9389–9403. Published online 2021 Aug 13. doi: 10.1093/nar/gkab689

PMCID:: PMC8450086

Abstract Article PDF–5.1M

Select item 836525311.

Nuclear cGAS: guard or prisoner?

Carina C de Oliveira Mann, Karl‐Peter Hopfner

EMBO J. 2021 Aug 16; 40(16): e108293. Published online 2021 Jul 12. doi: 10.15252/embj.2021108293

PMCID:: PMC8365253

Abstract Article PDF–2.1M

Select item 827493612.

Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity

Jiang Dai, Yi-Jiao Huang, Xinhua He, Ming Zhao, Xinzheng Wang, Zhao-Shan Liu, Wen Xue, Hong Cai, Xiao-Yan Zhan, Shao-Yi Huang, Kun He, Hongxia Wang, Na Wang, Zhihong Sang, Tingting Li, Qiu-Ying Han, Jie Mao, Xinwei Diao, Nan Song, Yuan Chen, Wei-Hua Li, Jiang-Hong Man, Ai-Ling Li, Tao Zhou, Zheng-Gang Liu, Xue-Min Zhang, Tao Li

Cell. Author manuscript; available in PMC 2021 Jul 12.

Published in final edited form as: Cell. 2019 Mar 7; 176(6): 1447–1460.e14. Published online 2019 Feb 21. doi: 10.1016/j.cell.2019.01.016

PMCID:: PMC8274936

Abstract Article PDF–1.1M

Select item 826020713.

Translation stress and collided ribosomes are co-activators of cGAS

Li Wan, Szymon Juszkiewicz, Daniel Blears, Prashanth Kumar Bajpe, Zhong Han, Peter Faull, Richard Mitter, Aengus Stewart, Ambrosius P. Snijders, Ramanujan S. Hegde, Jesper Q. Svejstrup

Mol Cell. 2021 Jul 1; 81(13): 2808–2822.e10. doi: 10.1016/j.molcel.2021.05.018

PMCID:: PMC8260207

Abstract Article

Select item 778469914.

Structural basis for nucleosome-mediated inhibition of cGAS activity

Duanfang Cao, Xiaonan Han, Xiaoyi Fan, Rui-Ming Xu, Xinzheng Zhang

Cell Res. 2020 Dec; 30(12): 1088–1097. Published online 2020 Oct 13. doi: 10.1038/s41422-020-00422-4

PMCID:: PMC7784699

Abstract Article PDF–3.2M

Select item 759105515.

Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

L. G. Webb, J. Veloz, J. Pintado-Silva, T. Zhu, M. V. Rangel, T. Mutetwa, L. Zhang, D. Bernal-Rubio, D. Figueroa, L. Carrau, R. Fenutria, U. Potla, St. P. Reid, J. S. Yount, K. A. Stapleford, S. Aguirre, A. Fernandez-Sesma

PLoS Pathog. 2020 Oct; 16(10): e1008999. Published online 2020 Oct 15. doi: 10.1371/journal.ppat.1008999