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Select item 66723481.

Sensory Deprivation Alters Aggrecan and Perineuronal Net Expression in the Mouse Barrel Cortex

Paulette A. McRae, Mary M. Rocco, Gail Kelly, Joshua C. Brumberg, Russell T. Matthews

J Neurosci. 2007 May 16; 27(20): 5405–5413. doi: 10.1523/JNEUROSCI.5425-06.2007

PMCID:: PMC6672348

Abstract Article PDF–470K

Select item 65961982.

Aggrecan Directs Extracellular Matrix-Mediated Neuronal Plasticity

Daire Rowlands, Kristian K. Lensjø, Tovy Dinh, Sujeong Yang, Melissa R. Andrews, Torkel Hafting, Marianne Fyhn, James W. Fawcett, Gunnar Dick

J Neurosci. 2018 Nov 21; 38(47): 10102–10113. doi: 10.1523/JNEUROSCI.1122-18.2018

PMCID:: PMC6596198

Abstract Article PDF–3.1M

Select item 65767883.

Aggrecan is required for chondrocyte differentiation in ATDC5 chondroprogenitor cells

Juanita K. Hodax, Jose Bernardo Quintos, Philip A. Gruppuso, Qian Chen, Salomi Desai, Chathuraka T. Jayasuriya

PLoS One. 2019; 14(6): e0218399. Published online 2019 Jun 17. doi: 10.1371/journal.pone.0218399

PMCID:: PMC6576788

Abstract Article PDF–1.5M

Select item 64295894.

Aggrecan Hypomorphism Compromises Articular Cartilage Biomechanical Properties and Is Associated with Increased Incidence of Spontaneous Osteoarthritis

Paolo Alberton, Hans Christian Dugonitsch, Bastian Hartmann, Ping Li, Zsuzsanna Farkas, Maximilian Michael Saller, Hauke Clausen-Schaumann, Attila Aszodi

Int J Mol Sci. 2019 Mar; 20(5): 1008. Published online 2019 Feb 26. doi: 10.3390/ijms20051008

PMCID:: PMC6429589

Abstract Article PDF–8.7M

Select item 56483365.

Dwarfism in Homozygous Agc1^CreERT Mice is Associated with Decreased Expression of Aggrecan

Harunur Rashid, Haiyan Chen, Mohammad Hassan, Amjad Javed

Genesis. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Genesis. 2017 Oct; 55(10): 10.1002/dvg.23070. Published online 2017 Sep 27. doi: 10.1002/dvg.23070

PMCID:: PMC5648336

Abstract Article PDF–1.0M

Select item 18662536.

Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair

Christopher B. Little, Clare T. Meeker, Suzanne B. Golub, Kate E. Lawlor, Pamela J. Farmer, Susan M. Smith, Amanda J. Fosang

J Clin Invest. 2007 Jun 1; 117(6): 1627–1636. Published online 2007 May 17. doi: 10.1172/JCI30765

Correction in:: J Clin Invest. 2008 Nov 3; 118(11): 3812.

PMCID:: PMC1866253

Abstract Article PDF–1.1M

Select item 11369447.

Mouse aggrecan, a large cartilage proteoglycan: protein sequence, gene structure and promoter sequence.

H Watanabe, L Gao, S Sugiyama, K Doege, K Kimata, Y Yamada

Biochem J. 1995 Jun 1; 308(Pt 2): 433–440. doi: 10.1042/bj3080433

PMCID:: PMC1136944

Summary Page Browse PDF–1.5M

Select item 10696128.

Matrix Metalloproteinases Are Not Essential for Aggrecan Turnover during Normal Skeletal Growth and Development

Christopher B. Little, Clare T. Meeker, Rosalind M. Hembry, Natalie A. Sims, Kate E. Lawlor, Sue B. Golub, Karena Last, Amanda J. Fosang

Mol Cell Biol. 2005 Apr; 25(8): 3388–3399. doi: 10.1128/MCB.25.8.3388-3399.2005

PMCID:: PMC1069612

Abstract Article PDF–1.2M

Select item 110188629.

Nerve growth factor receptor limits inflammation to promote remodeling and repair of osteoarthritic joints

Lan Zhao, Yumei Lai, Hongli Jiao, Jian Huang

Nat Commun. 2024; 15: 3225. Published online 2024 Apr 15. doi: 10.1038/s41467-024-47633-6

PMCID:: PMC11018862

Abstract Article PDF–5.2M

Select item 983291910.

AcanCreER lacks specificity to chondrocytes and targets periosteal progenitors in the fractured callus

Sanja Novak, Ivo Kalajzic

Bone. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Bone. 2023 Jan; 166: 116599. Published online 2022 Oct 26. doi: 10.1016/j.bone.2022.116599

PMCID:: PMC9832919

Abstract Article PDF–2.4M

Select item 967186411.

Early Ablation of Ccr2 in Aggrecan-expressing cells Following Knee Injury Ameliorates Joint Damage and Pain during Post-traumatic Osteoarthritis

Helen Willcockson, Huseyin Ozkan, Liubov Arbeeva, Esra Mucahit, Layla Musawwir, Lara Longobardi

Osteoarthritis Cartilage. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Osteoarthritis Cartilage. 2022 Dec; 30(12): 1616–1630. Published online 2022 Sep 6. doi: 10.1016/j.joca.2022.08.015

PMCID:: PMC9671864

Abstract Article PDF–3.1M

Select item 960268212.

Sensory Neuron-Specific Deletion of Tropomyosin Receptor Kinase A (TrkA) in Mice Abolishes Osteoarthritis (OA) Pain via NGF/TrkA Intervention of Peripheral Sensitization

InSug O-Sullivan, Ranjan Kc, Gurjit Singh, Vaskar Das, Kaige Ma, Xin Li, Fackson Mwale, Gina Votta-Velis, Benjamin Bruce, Arivarasu Natarajan Anbazhagan, Andre J. van Wijnen, Hee-Jeong Im

Int J Mol Sci. 2022 Oct; 23(20): 12076. Published online 2022 Oct 11. doi: 10.3390/ijms232012076

PMCID:: PMC9602682

Abstract Article PDF–4.2M

Select item 940223813.

DDRGK1 is required for the proper development and maintenance of the growth plate cartilage

Monika Weisz-Hubshman, Adetutu T Egunsula, Brian Dawson, Alexis Castellon, Ming-Ming Jiang, Yuqing Chen-Evenson, Yu Zhiyin, Brendan Lee, Yangjin Bae

Hum Mol Genet. 2022 Aug 15; 31(16): 2820–2830. Published online 2022 Apr 4. doi: 10.1093/hmg/ddac078

PMCID:: PMC9402238

Abstract Article PDF–1.9M

Select item 925331314.

Kindlin-2 loss in condylar chondrocytes causes spontaneous osteoarthritic lesions in the temporomandibular joint in mice

Yumei Lai, Wei Zheng, Minghao Qu, Christopher C. Xiao, Sheng Chen, Qing Yao, Weiyuan Gong, Chu Tao, Qinnan Yan, Peijun Zhang, Xiaohao Wu, Guozhi Xiao

Int J Oral Sci. 2022; 14: 33. Published online 2022 Jul 4. doi: 10.1038/s41368-022-00185-1

PMCID:: PMC9253313

Abstract Article PDF–7.7M

Select item 902701615.

Tau Protein Modulates Perineuronal Extracellular Matrix Expression in the TauP301L-acan Mouse Model

Sophie Schmidt, Max Holzer, Thomas Arendt, Mandy Sonntag, Markus Morawski

Biomolecules. 2022 Apr; 12(4): 505. Published online 2022 Mar 26. doi: 10.3390/biom12040505

PMCID:: PMC9027016

Abstract Article PDF–19M

Select item 874879816.

Kindlin-2 inhibits Nlrp3 inflammasome activation in nucleus pulposus to maintain homeostasis of the intervertebral disc

Sheng Chen, Xiaohao Wu, Yumei Lai, Di Chen, Xiaochun Bai, Sheng Liu, Yongchao Wu, Mingjue Chen, Yuxiao Lai, Huiling Cao, Zengwu Shao, Guozhi Xiao

Bone Res. 2022; 10: 5. Published online 2022 Jan 10. doi: 10.1038/s41413-021-00179-5

PMCID:: PMC8748798

Abstract Article PDF–7.7M

Select item 801525417.

LAMA: automated image analysis for the developmental phenotyping of mouse embryos

Neil R. Horner, Shanmugasundaram Venkataraman, Chris Armit, Ramón Casero, James M. Brown, Michael D. Wong, Matthijs C. van Eede, R. Mark Henkelman, Sara Johnson, Lydia Teboul, Sara Wells, Steve D. Brown, Henrik Westerberg, Ann-Marie Mallon

Development. 2021 Sep 15; 148(18): dev192955. Published online 2021 Mar 24. doi: 10.1242/dev.192955

PMCID:: PMC8015254

Abstract Article

Select item 701788618.

The Role of Dot1l in Prenatal and Postnatal Murine Chondrocytes and Trabecular Bone

Stephanie Y Jo, Miriam S Domowicz, Judith G Henry, Nancy B Schwartz

JBMR Plus. 2020 Feb; 4(2): e10254. Published online 2019 Dec 17. doi: 10.1002/jbm4.10254

PMCID:: PMC7017886

Abstract Article PDF–46M

Select item 624680319.

Deletion of Axin1 in condylar chondrocytes leads to osteoarthritis‐like phenotype in temporomandibular joint via activation of β‐catenin and FGF signaling

Yachuan Zhou, Bing Shu, Rong Xie, Jian Huang, Liwei Zheng, Xuedong Zhou, Guozhi Xiao, Lan Zhao, Di Chen

J Cell Physiol. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: J Cell Physiol. 2019 Feb; 234(2): 1720–1729. Published online 2018 Aug 2. doi: 10.1002/jcp.27043

PMCID:: PMC6246803

Abstract Article PDF–1.1M

Select item 591022820.

Roles of Ihh signaling in chondroprogenitor function in postnatal condylar cartilage

Naito Kurio, Cheri Saunders, Till E. Bechtold, Imad Salhab, Hyun-Duck Nah, Sayantani Sinha, Paul C. Billings, Maurizio Pacifici, Eiki Koyama

Matrix Biol. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Matrix Biol. 2018 Apr; 67: 15–31. Published online 2018 Feb 12. doi: 10.1016/j.matbio.2018.02.011

PMCID:: PMC5910228

Abstract Article PDF–3.2M

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PMC Links for Gene (Select 11595) (212)
PMC
Homo sapiens prolyl 4-hydroxylase subunit alpha 1 (P4HA1), transcript variant 1,...
Homo sapiens prolyl 4-hydroxylase subunit alpha 1 (P4HA1), transcript variant 1, mRNA
gi|1890268087|ref|NM_000917.4|

Nucleotide
MAG: hypothetical protein CBD23_000690 [Gammaproteobacteria bacterium TMED163]
MAG: hypothetical protein CBD23_000690 [Gammaproteobacteria bacterium TMED163]
gi|1519675655|gb|RPG46771.1||gnl|WG M|CBD23_000690

Protein
MAG: hypothetical protein CBD23_000700 [Gammaproteobacteria bacterium TMED163]
MAG: hypothetical protein CBD23_000700 [Gammaproteobacteria bacterium TMED163]
gi|1519675657|gb|RPG46773.1||gnl|WG M|CBD23_000700

Protein
an22h09.x1 Gessler Wilms tumor Homo sapiens cDNA clone IMAGE:1699457 3' similar ...
an22h09.x1 Gessler Wilms tumor Homo sapiens cDNA clone IMAGE:1699457 3' similar to gb:M24486 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PRECURSOR (HUMAN), mRNA sequence
gi|3336451|gnl|dbEST|1800537|gb|AI0 .1|

Nucleotide

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