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Select item 76456211.

Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS

Veselina Petrova, Craig S. Pearson, Jared Ching, James R. Tribble, Andrea G. Solano, Yunfei Yang, Fiona M. Love, Robert J. Watt, Andrew Osborne, Evan Reid, Pete A. Williams, Keith R. Martin, Herbert M. Geller, Richard Eva, James W. Fawcett

Nat Commun. 2020; 11: 5614. Published online 2020 Nov 5. doi: 10.1038/s41467-020-19436-y

PMCID:: PMC7645621

Abstract Article PDF–6.4M

Select item 24438342.

The Role of ZFYVE27/Protrudin in Hereditary Spastic Paraplegia

Monica Martignoni, Elena Riano, Elena I. Rugarli

Am J Hum Genet. 2008 Jul 11; 83(1): 127–128. Published online 2008 Jul 3. doi: 10.1016/j.ajhg.2008.05.014

PMCID:: PMC2443834

Article PDF–240K

Select item 74017963.

Protrudin-mediated ER–endosome contact sites promote MT1-MMP exocytosis and cell invasion

Nina Marie Pedersen, Eva Maria Wenzel, Ling Wang, Sandra Antoine, Philippe Chavrier, Harald Stenmark, Camilla Raiborg

J Cell Biol. 2020 Aug 3; 219(8): e202003063. Published online 2020 Jun 1. doi: 10.1083/jcb.202003063

PMCID:: PMC7401796

Abstract Article PDF–9.3M

Select item 15595034.

ZFYVE27 (SPG33), a Novel Spastin-Binding Protein, Is Mutated in Hereditary Spastic Paraplegia

Ashraf U. Mannan, Philip Krawen, Simone M. Sauter, Johann Boehm, Agnieszka Chronowska, Walter Paulus, Juergen Neesen, Wolfgang Engel

Am J Hum Genet. 2006 Aug; 79(2): 351–357. Published online 2006 Jun 1. doi: 10.1086/504927

PMCID:: PMC1559503

Abstract Article PDF–2.3M

Select item 74863835.

Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation

Michiko Shirane, Mariko Wada, Keiko Morita, Nahoki Hayashi, Reina Kunimatsu, Yuki Matsumoto, Fumiko Matsuzaki, Hirokazu Nakatsumi, Keisuke Ohta, Yasushi Tamura, Keiichi I. Nakayama

Nat Commun. 2020; 11: 4576. Published online 2020 Sep 11. doi: 10.1038/s41467-020-18413-9

PMCID:: PMC7486383

Abstract Article PDF–3.9M

Select item 68797476.

Protrudin modulates seizure activity through GABA_A receptor regulation

Xi Lu, Yong Yang, Ruijiao Zhou, Yun Li, Yi Yang, Xuefeng Wang

Cell Death Dis. 2019 Dec; 10(12): 897. Published online 2019 Nov 27. doi: 10.1038/s41419-019-2118-8

PMCID:: PMC6879747

Abstract Article PDF–3.2M

Select item 26794787.

Promotion of Neurite Extension by Protrudin Requires Its Interaction with Vesicle-associated Membrane Protein-associated Protein

Shotaro Saita, Michiko Shirane, Tohru Natume, Shun-ichiro Iemura, Keiichi I. Nakayama

J Biol Chem. 2009 May 15; 284(20): 13766–13777. doi: 10.1074/jbc.M807938200

PMCID:: PMC2679478

Abstract Article PDF–1.8M

Select item 40363118.

Protrudin Regulates Endoplasmic Reticulum Morphology and Function Associated with the Pathogenesis of Hereditary Spastic Paraplegia

Yutaka Hashimoto, Michiko Shirane, Fumiko Matsuzaki, Shotaro Saita, Takafumi Ohnishi, Keiichi I. Nakayama

J Biol Chem. 2014 May 9; 289(19): 12946–12961. Published online 2014 Mar 25. doi: 10.1074/jbc.M113.528687

PMCID:: PMC4036311

Abstract Article PDF–4.4M

Select item 37737759.

Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation

Jaerak Chang, Seongju Lee, Craig Blackstone

Proc Natl Acad Sci U S A. 2013 Sep 10; 110(37): 14954–14959. Published online 2013 Aug 22. doi: 10.1073/pnas.1307391110

PMCID:: PMC3773775

Abstract Article PDF–1.5M

Select item 322647810.

Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation

Fumiko Matsuzaki, Michiko Shirane, Masaki Matsumoto, Keiichi I. Nakayama

Mol Biol Cell. 2011 Dec 1; 22(23): 4602–4620. doi: 10.1091/mbc.E11-01-0068

PMCID:: PMC3226478

Abstract Article PDF–5.5M

Select item 1062778611.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 138022512.

A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease

Andrew Grupe, Yonghong Li, Charles Rowland, Petra Nowotny, Anthony L. Hinrichs, Scott Smemo, John S. K. Kauwe, Taylor J. Maxwell, Sara Cherny, Lisa Doil, Kristina Tacey, Ryan van Luchene, Amanda Myers, Fabienne Wavrant-De Vrièze, Mona Kaleem, Paul Hollingworth, Luke Jehu, Catherine Foy, Nicola Archer, Gillian Hamilton, Peter Holmans, Chris M. Morris, Joseph Catanese, John Sninsky, Thomas J. White, John Powell, John Hardy, Michael O’Donovan, Simon Lovestone, Lesley Jones, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate

Am J Hum Genet. 2006 Jan; 78(1): 78–88. Published online 2005 Nov 15. doi: 10.1086/498851

PMCID:: PMC1380225

Abstract Article PDF–329K

Select item 903755413.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 895155614.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 488219015.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 943393816.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 851385317.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 484160718.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect

Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva

RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030

PMCID:: PMC4841607

Abstract Article PDF–1.6M

Select item 319082619.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 910523520.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

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PMC Links for Gene (Select 118813) (29)
PMC
protrudin isoform X5 [Homo sapiens]
protrudin isoform X5 [Homo sapiens]
gi|1034566363|ref|XP_016871135.1|

Protein
Homo sapiens zinc finger FYVE-type containing 27 (ZFYVE27), transcript variant 2...
Homo sapiens zinc finger FYVE-type containing 27 (ZFYVE27), transcript variant 20, mRNA
gi|1883542788|ref|NM_001385886.1|

Nucleotide
disintegrin and metalloproteinase domain-containing protein 33 isoform X4 [Homo ...
disintegrin and metalloproteinase domain-containing protein 33 isoform X4 [Homo sapiens]
gi|2462581619|ref|XP_054180024.1|

Protein

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