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Select item 53425361.

FRMD6 inhibits human glioblastoma growth and progression by negatively regulating activity of receptor tyrosine kinases

Yin Xu, Kaiqiang Wang, Qin Yu

Oncotarget. 2016 Oct 25; 7(43): 70080–70091. Published online 2016 Sep 20. doi: 10.18632/oncotarget.12148

PMCID:: PMC5342536

Abstract Article PDF–8.2M

Select item 33263472.

Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease

Mun-Gwan Hong, Chandra A. Reynolds, Adina L. Feldman, Mikael Kallin, Jean-Charles Lambert, Philippe Amouyel, Erik Ingelsson, Nancy L. Pedersen, Jonathan A. Prince

Hum Mutat. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Hum Mutat. 2012 Mar; 33(3): 521–529. Published online 2012 Jan 23. doi: 10.1002/humu.22009

PMCID:: PMC3326347

Abstract Article PDF–380K

Select item 53863813.

CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells

Xiaona Mao, Pingping Li, Yaochun Wang, Zheyong Liang, Jie Liu, Juan Li, Yina Jiang, Gang Bao, Lei Li, Bofeng Zhu, Yu Ren, Xinhan Zhao, Jianmin Zhang, Yu Liu, Jin Yang, Peijun Liu

Cell Death Dis. 2017 Jan; 8(1): e2546. Published online 2017 Jan 12. doi: 10.1038/cddis.2016.478

PMCID:: PMC5386381

Abstract Article PDF–5.7M

Select item 40768134.

A genome-wide gene–environment interaction analysis for tobacco smoke and lung cancer susceptibility

Ruyang Zhang, Minjie Chu, Yang Zhao, Chen Wu, Huan Guo, Yongyong Shi, Juncheng Dai, Yongyue Wei, Guangfu Jin, Hongxia Ma, Jing Dong, Honggang Yi, Jianling Bai, Jianhang Gong, Chongqi Sun, Meng Zhu, Tangchun Wu, Zhibin Hu, Dongxin Lin, Hongbing Shen, Feng Chen

Carcinogenesis. 2014 Jul; 35(7): 1528–1535. Published online 2014 Mar 22. doi: 10.1093/carcin/bgu076

PMCID:: PMC4076813

Abstract Article PDF–1.2M

Select item 32472585.

A Genome-Wide Association Study of the Protein C Anticoagulant Pathway

Georgios Athanasiadis, Alfonso Buil, Juan Carlos Souto, Montserrat Borrell, Sonia López, Angel Martinez-Perez, Mark Lathrop, Jordi Fontcuberta, Laura Almasy, José Manuel Soria

PLoS One. 2011; 6(12): e29168. Published online 2011 Dec 28. doi: 10.1371/journal.pone.0029168

PMCID:: PMC3247258

Abstract Article PDF–295K

Select item 29004296.

Voxelwise genome-wide association study (vGWAS)

Jason L. Stein, Xue Hua, Suh Lee, April J. Ho, Alex D. Leow, Arthur W. Toga, Andrew J. Saykin, Li Shen, Tatiana Foroud, Nathan Pankratz, Matthew J. Huentelman, David W. Craig, Jill D. Gerber, April N. Allen, Jason J. Corneveaux, Bryan M. DeChairo, Steven G. Potkin, Michael W. Weiner, Paul M. Thompson

Neuroimage. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Neuroimage. 2010 Nov 15; 53(3): 1160–1174. Published online 2010 Feb 17. doi: 10.1016/j.neuroimage.2010.02.032

PMCID:: PMC2900429

Abstract Article PDF–4.7M

Select item 27195817.

Hippocampal Atrophy as a Quantitative Trait in a Genome-Wide Association Study Identifying Novel Susceptibility Genes for Alzheimer's Disease

Steven G. Potkin, Guia Guffanti, Anita Lakatos, Jessica A. Turner, Frithjof Kruggel, James H. Fallon, Andrew J. Saykin, Alessandro Orro, Sara Lupoli, Erika Salvi, Michael Weiner, Fabio Macciardi, for the Alzheimer's Disease Neuroimaging Initiative

PLoS One. 2009; 4(8): e6501. Published online 2009 Aug 7. doi: 10.1371/journal.pone.0006501

PMCID:: PMC2719581

Abstract Article PDF–289K

Select item 59806568.

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease

SJ Furney, A Simmons, G Breen, I Pedroso, K Lunnon, P Proitsi, A Hodges, J Powell, L-O Wahlund, I Kloszewska, P Mecocci, H Soininen, M Tsolaki, B Vellas, C Spenger, M Lathrop, L Shen, S Kim, AJ Saykin, MW Weiner, S Lovestone

Mol Psychiatry. Author manuscript; available in PMC 2018 May 31.

Published in final edited form as: Mol Psychiatry. 2011 Nov; 16(11): 1130–1138. Published online 2010 Nov 30. doi: 10.1038/mp.2010.123

PMCID:: PMC5980656

Abstract Article PDF–439K

Select item 58914299.

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics

Thomas O'Loughlin, Thomas A Masters, Folma Buss

EMBO Rep. 2018 Apr; 19(4): e44884. Published online 2018 Feb 21. doi: 10.15252/embr.201744884

PMCID:: PMC5891429

Abstract Article PDF–9.1M

Select item 401998110.

Interaction proteome of human Hippo signaling: modular control of the co‐activator YAP1

Simon Hauri, Alexander Wepf, Audrey van Drogen, Markku Varjosalo, Nic Tapon, Ruedi Aebersold, Matthias Gstaiger

Mol Syst Biol. 2013; 9: 713. Published online 2013 Dec 20. doi: 10.1002/msb.201304750

PMCID:: PMC4019981

Abstract Article PDF–915K

Select item 1091686611.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 631495712.

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders

Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu

Nat Genet. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z

PMCID:: PMC6314957

Abstract Article PDF–1.3M

Select item 904055613.

A protein interaction landscape of breast cancer

Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan

Science. Author manuscript; available in PMC 2022 Apr 26.

Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066

PMCID:: PMC9040556

Abstract Article PDF–2.2M

Select item 943393814.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 318838815.

Leveraging the power of next-generation sequencing to generate interactome datasets

Haiyuan Yu, Leah Tardivo, Stanley Tam, Evan Weiner, Fana Gebreab, Changyu Fan, Nenad Svrzikapa, Tomoko Hirozane-Kishikawa, Edward Rietman, Xinping Yang, Julie Sahalie, Kourosh Salehi-Ashtiani, Tong Hao, Michael E. Cusick, David E. Hill, Frederick P. Roth, Pascal Braun, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: Nat Methods. 2011 Jun; 8(6): 478–480. Published online 2011 Apr 24. doi: 10.1038/nmeth.1597

PMCID:: PMC3188388

Abstract Article PDF–932K

Select item 184794816.

Large-scale mapping of human protein–protein interactions by mass spectrometry

Rob M Ewing, Peter Chu, Fred Elisma, Hongyan Li, Paul Taylor, Shane Climie, Linda McBroom-Cerajewski, Mark D Robinson, Liam O'Connor, Michael Li, Rod Taylor, Moyez Dharsee, Yuen Ho, Adrian Heilbut, Lynda Moore, Shudong Zhang, Olga Ornatsky, Yury V Bukhman, Martin Ethier, Yinglun Sheng, Julian Vasilescu, Mohamed Abu-Farha, Jean-Philippe Lambert, Henry S Duewel, Ian I Stewart, Bonnie Kuehl, Kelly Hogue, Karen Colwill, Katharine Gladwish, Brenda Muskat, Robert Kinach, Sally-Lin Adams, Michael F Moran, Gregg B Morin, Thodoros Topaloglou, Daniel Figeys

Mol Syst Biol. 2007; 3: 89. Published online 2007 Mar 13. doi: 10.1038/msb4100134

PMCID:: PMC1847948

Abstract Article PDF–440K

Select item 674264617.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 698120618.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 582692619.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 616668220.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

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PMC Links for Gene (Select 122786) (30)
PMC
PREDICTED: Homo sapiens FERM domain containing 6 (FRMD6), transcript variant X22...
PREDICTED: Homo sapiens FERM domain containing 6 (FRMD6), transcript variant X22, mRNA
gi|2217296283|ref|XM_047430935.1|

Nucleotide
FERM domain-containing protein 6 isoform X2 [Homo sapiens]
FERM domain-containing protein 6 isoform X2 [Homo sapiens]
gi|2217296278|ref|XP_047286888.1|

Protein
PREDICTED: Homo sapiens FERM domain containing 6 (FRMD6), transcript variant X5,...
PREDICTED: Homo sapiens FERM domain containing 6 (FRMD6), transcript variant X5, mRNA
gi|2462538809|ref|XM_054375367.1|

Nucleotide
PREDICTED: Homo sapiens FERM domain containing 6 (FRMD6), transcript variant X14...
PREDICTED: Homo sapiens FERM domain containing 6 (FRMD6), transcript variant X14, mRNA
gi|2217296269|ref|XM_006720030.2|

Nucleotide

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